Heat-Killed Lactococcus Lactis KC24 Ameliorates Scopolamine-Induced Memory Impairment in ICR Mice.

Lactococcus lactis Animal model Memory Neuroprotective effect Probiotics

Journal

Probiotics and antimicrobial proteins
ISSN: 1867-1314
Titre abrégé: Probiotics Antimicrob Proteins
Pays: United States
ID NLM: 101484100

Informations de publication

Date de publication:
19 Jun 2024
Historique:
accepted: 17 04 2024
medline: 19 6 2024
pubmed: 19 6 2024
entrez: 19 6 2024
Statut: aheadofprint

Résumé

Heat-killed Lactococcus lactis KC24 (H-KC24) has been examined for its neuroprotective effects in SH-SY5Y cells. We hypothesized that H-KC24 could alleviate memory impairment through the gut-brain axis. Scopolamine (1 mg/kg/day) was administered to ICR mice to induce memory impairment. Low- and high-dose H-KC24 cells (1 × 10

Identifiants

pubmed: 38896221
doi: 10.1007/s12602-024-10268-6
pii: 10.1007/s12602-024-10268-6
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Références

WHO (World Health Organization) (2019) Risk Reduction of Cognitive Decline and Dementia: WHO Guidelines, WHO 2019:1–96. https://www.who.int/publications/i/item/9789241550543 . Accessed 23 November 2023
Breijyeh Z, Karaman R (2020) Comprehensive review on Alzheimer’s disease: Causes and treatment. Molecules 25:5789. https://doi.org/10.3390/molecules25245789
doi: 10.3390/molecules25245789
D’Argenio V, Sarnataro D (2021) Probiotics, prebiotics and their role in Alzheimer’s disease. Neural Regen Res 16:1768–1769. https://doi.org/10.4103/1673-5374.306072
doi: 10.4103/1673-5374.306072
Rahman MM, Lendel C (2021) Extracellular protein components of amyloid plaques and their roles in Alzheimer’s disease pathology. Mol Neurodegener 16:59. https://doi.org/10.1186/s13024-021-00465-0
doi: 10.1186/s13024-021-00465-0
Huang Q, Liao C, Ge F, Ao J, Liu T (2020) Acetylcholine bidirectionally regulates learning and memory. J Neurorestoratology 10:100002. https://doi.org/10.1016/j.jnrt.2022.100002
doi: 10.1016/j.jnrt.2022.100002
Hopkins AL, Groom CR (2002) The druggable genome. Nat Rev Drug Discov 2002:727–730. https://doi.org/10.1038/nrd892
Parra I, Martínez I, Vásquez-Celaya L, Gongora-Alfaro JL, Tizabi Y, Mendieta L (2023) Neuroprotective and immunomodulatory effects of probiotics in a rat model of Parkinson’s disease. Neurotox Res 41:187–200. https://doi.org/10.1007/s12640-022-00627-y
doi: 10.1007/s12640-022-00627-y
Rahimzadegan M, Soodi M (2018) Comparison of memory impairment and oxidative stress following single or repeated doses administration of scopolamine in rat hippocampus. Basic Clin Neurosci 9:5–14. https://doi.org/10.29252/NIRP.BCN.9.1.5
doi: 10.29252/NIRP.BCN.9.1.5
Akram M, Nawaz A (2017) Effects of medicinal plants on Alzheimer’s disease and memory deficits. Neural Regen Res 12:660–670. https://doi.org/10.4103/1673-5374.205108
doi: 10.4103/1673-5374.205108
Geng M, Zhao F, Lu H, Fang L, Wang J, Liu C et al. (2022) Insights into the hippocampus proteome and phosphorylation modification alterations in C57BL/6 revealed the memory improvement mechanisms of a walnut-derived peptide. Food Res Int 156:111311. https://doi.org/10.1016/j.foodres.2022.111311
doi: 10.1016/j.foodres.2022.111311
Cheon SY, Koo BN, Kim SY, Kam EH, Nam J, Kim EJ (2021) Scopolamine promotes neuroinflammation and delirium-like neuropsychiatric disorder in mice. Sci Rep 11:8376. https://doi.org/10.1038/s41598-021-87790-y
doi: 10.1038/s41598-021-87790-y
Anand A, Khurana N, Ali N, AlAsmari AF, Alharbi M, Waseem M et al. (2022) Ameliorative effect of vanillin on scopolamine-induced dementia-like cognitive impairment in a mouse model. Front Neurosci 16:1005972. https://doi.org/10.3389/fnins.2022.1005972
doi: 10.3389/fnins.2022.1005972
Bae HJ, Sowndhararajan K, Park HB, Kim SY, Kim S, Kim DH et al (2019) Danshensu attenuates scopolamine and amyloid β-induced cognitive impairments through the activation of PKA-CREB signaling in mice. Neurochem Int 131:104537. https://doi.org/10.1016/j.neuint.2019.104537
doi: 10.1016/j.neuint.2019.104537
Cacabelos R (2007) Donepezil in Alzheimer’s disease: from conventional trials to pharmacogenetics. Neuropsychiatr Dis Treat 3:303–333
Sharma K (2019) Cholinesterase inhibitors as Alzheimer’s therapeutics (review). Mol Med Rep 20:1479–1487. https://doi.org/10.3892/mmr.2019.10374
doi: 10.3892/mmr.2019.10374
Lee NK, Han KJ, Son SH, Eom SJ, Lee SK, Paik HD (2015) Multifunctional effect of probiotic Lactococcus lactis KC24 isolated from kimchi. LWT-Food Sci Technol 64:1036–1041. https://doi.org/10.1016/j.lwt.2015.07.019
doi: 10.1016/j.lwt.2015.07.019
Lim SM, Lee NK, Paik HD (2020) Potential neuroprotective effects of heat-killed Lactococcus lactis KC24 using SH-SY5Y cells against oxidative stress induced by hydrogen peroxide. Food Sci Biotechnol 29:1735–1740. https://doi.org/10.1007/s10068-020-00830-7
doi: 10.1007/s10068-020-00830-7
Salahuddin HS, Attaullah S, Shah SA, Khan SU, Zahid M, Ullah M et al (2023) Ranuncoside’s attenuation of scopolamine-induced memory impairment in mice via Nrf2 and NF-κB signaling. Saudi Pharm J 31:101702. https://doi.org/10.1016/j.jsps.2023.101702
doi: 10.1016/j.jsps.2023.101702
Lee NK, Park YS, Kang DK, Paik HD (2023) Paraprobiotics: definition, manufacturing methods, and functionality. Food Sci Biotechnol 32:1981–1991. https://doi.org/10.1007/s10068-023-01378-y
doi: 10.1007/s10068-023-01378-y
Dinan TG, Stanton C, Cryan JF (2013) Psychobiotics: a novel class of psychotropic. Biol Psychiatry 74:720–726. https://doi.org/10.1016/j.biopsych.2013.05.001
doi: 10.1016/j.biopsych.2013.05.001
Ma Y, Liu T, Fu J, Fu S, Hu C, Sun B et al (2019) Lactobacillus acidophilus exerts neuroprotective effects in mice with traumatic brain injury. J Nutr 149:1543–1552. https://doi.org/10.1093/jn/nxz105
doi: 10.1093/jn/nxz105
Sarkar A, Lehto SM, Harty S, Dinan TG, Cryan JF, Burnet PWJ (2016) Psychobiotics and the manipulation of bacteria-gut-brain signals. Trends Neurosci 39:763–781. https://doi.org/10.1016/j.tins.2016.09.002
doi: 10.1016/j.tins.2016.09.002
Jiang T, Yu JT, Tian Y, Tan L (2013) Epidemiology and etiology of Alzheimer’s disease: from genetic to non-genetic factors. Curr Alzheimer Res 10:852–867. https://doi.org/10.2174/15672050113109990155
doi: 10.2174/15672050113109990155
Su A, Ma G, Ma N, Pei F, Yang W, Hu Q (2023) Effects of Flammulina velutipes polysaccharides on gut microbiota composition and metabolism in vitro fermentation. Food Sci Biotechnol 32:361–369. https://doi.org/10.1007/s10068-022-01192-y
doi: 10.1007/s10068-022-01192-y
Gul S, Attaullah S, Alsugoor MH, Bawazeer S, Shah SA, Khan S et al (2023) Folicitin abrogates scopolamine induced oxidative stress, hyperlipidemia mediated neuronal synapse and memory dysfunction in mice. Heliyon 9:e16930. https://doi.org/10.1016/j.heliyon.2023.e16930
doi: 10.1016/j.heliyon.2023.e16930
Zuliani G, Trentini A, Brombo G, Rosta V, Guasti P, Romagnoli T et al (2021) Serum beta-secretase 1 (BACE1) activity increases in patients with mild cognitive impairment. J Neurochem 159:629–637. https://doi.org/10.1111/jnc.15513
doi: 10.1111/jnc.15513
Jagust WJ, Teunissen CE, DeCarli C (2023) The complex pathway between amyloid β and cognition: implications for therapy. Lancet Neurol 22:847–857. https://doi.org/10.1016/S1474-4422(23)00128-X
doi: 10.1016/S1474-4422(23)00128-X
Sehar U, Rawat P, Reddy AP, Kopel J, Reddy PH (2022) Amyloid beta in aging and Alzheimer’s disease. Int J Mol Sci 23:12924. https://doi.org/10.3390/ijms232112924
doi: 10.3390/ijms232112924
Jack CR Jr, Bennett DA, Blennow K, Carrillo MC, Dunn B, Haeberlein SB et al (2018) NIA-AA research framework: Toward a biological definition of Alzheimer’s disease. Alzheimers Dement 14:535–562. https://doi.org/10.1016/j.jalz.2018.02.018
doi: 10.1016/j.jalz.2018.02.018
Kim J, Kaang BK (2023) Cyclic AMP response element-binding protein (CREB) transcription factor in astrocytic synaptic communication. Front Synaptic Neurosci 14:1059918. https://doi.org/10.3389/fnsyn.2022.1059918
doi: 10.3389/fnsyn.2022.1059918
Carriba P, Pardo L, Parra-Damas A, Lichtenstein MP, Saura CA, Pujol A et al (2012) ATP and noradrenaline activate CREB in astrocytes via noncanonical Ca
Hyun JH, Yu HS, Woo IK, Lee GW, Lee NK, Paik HD (2023) Anti-inflammatory activities of levilactobacillus brevis KU15147 in RAW 264.7 cells stimulated with lipopolysaccharide on attenuating NF-κB, AP-1, and MAPK signaling pathways. Food Sci Biotechnol 32:2105–2115. https://doi.org/10.1007/s10068-023-01318-w
doi: 10.1007/s10068-023-01318-w
Lorenzo-López L, Lema-Arranz C, Fernández-Bertólez N, Costa S, Costa C, Teixeira JP et al (2022) Relationship between DNA damage measured by the comet-assay and cognitive function. Mutat Res Genet Toxicol Environ Mutagen 883–884. https://doi.org/10.1016/j.mrgentox.2022.503557
Jung IH, Jung MA, Kim EJ, Han MJ, Kim DH (2012) Lactobacillus pentosus var. plantarum C29 protects scopolamine-induced memory deficit in mice. J Appl Microbiol 113:1498–1506. https://doi.org/10.1111/j.1365-2672.2012.05437.x
doi: 10.1111/j.1365-2672.2012.05437.x
Lee HJ, Lim SM, Kim DH (2018) Lactobacillus johnsonii cjlj103 attenuates scopolamine-induced memory impairment in mice by increasing BDNF expression and inhibiting NF-κB activation. J Microbiol Biotechnol 28:1443–1446. https://doi.org/10.4014/jmb.1805.05025
doi: 10.4014/jmb.1805.05025

Auteurs

Na-Kyoung Lee (NK)

Department of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, 05029, Korea.

Yunjung Lee (Y)

Department of Food and Nutrition, Kyungnam University, Changwon, 51767, Korea.

Ji Ye Park (JY)

Department of Food and Nutrition, Kyungnam University, Changwon, 51767, Korea.

Eunju Park (E)

Department of Food and Nutrition, Kyungnam University, Changwon, 51767, Korea. pej@kyungnam.ac.kr.

Hyun-Dong Paik (HD)

Department of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, 05029, Korea. hdpaik@konkuk.ac.kr.

Classifications MeSH