γ-Cyclodextrin hydrogel for the sustained release of josamycin for potential ocular application.

Hydrogels / chemistry Delayed-Action Preparations gamma-Cyclodextrins / chemistry Solubility Drug Liberation Drug Delivery Systems / methods Glaucoma / drug therapy Anti-Bacterial Agents / administration & dosage Drug Carriers / chemistry Animals Humans Cross-Linking Reagents / chemistry
drug delivery fibrosis glaucoma hydrogel josamycin γ-cyclodextrin

Journal

Drug delivery
ISSN: 1521-0464
Titre abrégé: Drug Deliv
Pays: England
ID NLM: 9417471

Informations de publication

Date de publication:
Dec 2024
Historique:
medline: 20 6 2024
pubmed: 20 6 2024
entrez: 20 6 2024
Statut: ppublish

Résumé

Glaucoma is the leading cause of blindness worldwide. However, its surgical treatment, in particular via trabeculectomy, can be complicated by fibrosis. In current clinical practice, application of the drug, Mitomycin C, prevents or delays fibrosis, but can lead to additional side effects, such as bleb leakage and hypotony. Previous

Identifiants

DOI: 10.1080/10717544.2024.2361168 PMID: 38899440
pubmed: 38899440
doi: 10.1080/10717544.2024.2361168
doi:

Substances chimiques

Hydrogels 0
Delayed-Action Preparations 0
gamma-Cyclodextrins 0
gamma-cyclodextrin KZJ0BYZ5VA
Anti-Bacterial Agents 0
Drug Carriers 0
Cross-Linking Reagents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2361168

Auteurs

Jennifer Huling (J)

Institute for Biomedical Engineering, Rostock University Medical Center, Rostock, Germany.

Stefan Oschatz (S)

Institute for Biomedical Engineering, Rostock University Medical Center, Rostock, Germany.

Helge Lange (H)

Institute for Biomedical Engineering, Rostock University Medical Center, Rostock, Germany.

Katharina Anna Sterenczak (KA)

Department of Ophthalmology, Rostock University Medical Center, Rostock, Germany.

Thomas Stahnke (T)

Department of Ophthalmology, Rostock University Medical Center, Rostock, Germany.

Jana Markhoff (J)

Institute for Biomedical Engineering, Rostock University Medical Center, Rostock, Germany.

Oliver Stachs (O)

Department of Ophthalmology, Rostock University Medical Center, Rostock, Germany.

Steffen Möller (S)

Institute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, Rostock, Germany.

Nasrullah Undre (N)

Institute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, Rostock, Germany.

Anita Peil (A)

Institute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, Rostock, Germany.

Anselm Jünemann (A)

Department of Ophthalmology, Rostock University Medical Center, Rostock, Germany.

Niels Grabow (N)

Institute for Biomedical Engineering, Rostock University Medical Center, Rostock, Germany.
Department Life, Light & Matter (LLM), University of Rostock, Rostock, Germany.

Georg Fuellen (G)

Institute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, Rostock, Germany.

Thomas Eickner (T)

Institute for Biomedical Engineering, Rostock University Medical Center, Rostock, Germany.

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Classifications MeSH

questionsmedicales.fr › Préparations pharmaceutiques › Colloïdes › Gels › Hydrogels › γ-Cyclodextrin hydrogel for the sustained...
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Systèmes de délivrance de médicaments › Préparations à action retardée › γ-Cyclodextrin hydrogel for the sustained...
questionsmedicales.fr › Glucides › Polyosides › Glucanes › Amidon › Dextrine › Cyclodextrines › Cyclodextrines gamma › γ-Cyclodextrin hydrogel for the sustained...
questionsmedicales.fr › Phénomènes chimiques › Solubilité › γ-Cyclodextrin hydrogel for the sustained...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Pharmacocinétique › Libération de médicament › γ-Cyclodextrin hydrogel for the sustained...
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Systèmes de délivrance de médicaments › γ-Cyclodextrin hydrogel for the sustained...
questionsmedicales.fr › Maladies de l'oeil › Hypertension oculaire › Glaucome › γ-Cyclodextrin hydrogel for the sustained...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › γ-Cyclodextrin hydrogel for the sustained...
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Systèmes de délivrance de médicaments › Vecteurs de médicaments › γ-Cyclodextrin hydrogel for the sustained...
questionsmedicales.fr › Eucaryotes › Animaux › γ-Cyclodextrin hydrogel for the sustained...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › γ-Cyclodextrin hydrogel for the sustained...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Indicateurs et réactifs › Réactifs réticulants › γ-Cyclodextrin hydrogel for the sustained...