Hypertriglyceridemia Results From an Impaired Catabolism of Triglyceride-Rich Lipoproteins in

kinetics lipodystrophy lipoprotein lipase perilipin-1 triglycerides

Journal

Arteriosclerosis, thrombosis, and vascular biology
ISSN: 1524-4636
Titre abrégé: Arterioscler Thromb Vasc Biol
Pays: United States
ID NLM: 9505803

Informations de publication

Date de publication:
20 Jun 2024
Historique:
medline: 20 6 2024
pubmed: 20 6 2024
entrez: 20 6 2024
Statut: aheadofprint

Résumé

Pathogenic variants in We performed an in vivo lipoprotein kinetic study in 6 affected patients compared with 13 healthy controls and 8 patients with type 2 diabetes. Glucose and lipid parameters, including plasma LPL (lipoprotein lipase) mass, were measured. Patients with We show that hypertriglyceridemia associated with

Sections du résumé

BACKGROUND UNASSIGNED
Pathogenic variants in
METHODS UNASSIGNED
We performed an in vivo lipoprotein kinetic study in 6 affected patients compared with 13 healthy controls and 8 patients with type 2 diabetes. Glucose and lipid parameters, including plasma LPL (lipoprotein lipase) mass, were measured.
RESULTS UNASSIGNED
Patients with
CONCLUSIONS UNASSIGNED
We show that hypertriglyceridemia associated with

Identifiants

DOI: 10.1161/ATVBAHA.124.320774 PMID: 38899472
pubmed: 38899472
doi: 10.1161/ATVBAHA.124.320774
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Bruno Vergès (B)

Department of Endocrinology, Diabetology and Metabolic Diseases, University Hospital, Dijon, France. (B.V., A.R.).
University of Burgundy, INSERM CTM UMR1231, Dijon, France (B.V., L.D., A.R.).
ORCID: 0000-0001-8957-629X

Marie-Christine Vantyghem (MC)

Department of Endocrinology, Diabetology, and Metabolism, University of Lille, CHU Lille, France (M.C.V.).
Université Lille, U1190 Translational Research for Diabetes, INSERM, Institut Pasteur de Lille, France (M.C.V.).

Yves Reznik (Y)

Department of Endocrinology, University Hospital, Caen, France (Y.R.).
ORCID: 0000-0002-6267-8058

Laurence Duvillard (L)

Department of Biochemistry, University Hospital, Dijon, France. (L.D.).
University of Burgundy, INSERM CTM UMR1231, Dijon, France (B.V., L.D., A.R.).

Alexia Rouland (A)

Department of Endocrinology, Diabetology and Metabolic Diseases, University Hospital, Dijon, France. (B.V., A.R.).
University of Burgundy, INSERM CTM UMR1231, Dijon, France (B.V., L.D., A.R.).
ORCID: 0000-0003-0727-2052

Emilie Capel (E)

Inserm U938, Saint-Antoine Research Centre, Institute of Cardiometabolism and Nutrition, Sorbonne University, Paris, France (E.C., C.V.).
ORCID: 0000-0001-8396-2843

Corinne Vigouroux (C)

Inserm U938, Saint-Antoine Research Centre, Institute of Cardiometabolism and Nutrition, Sorbonne University, Paris, France (E.C., C.V.).
Department of Molecular Biology and Genetics, Assistance Publique-Hôpitaux de Paris, Saint-Antoine University Hospital, France. (C.V.).
Department of Endocrinology, Diabetology and Reproductive Endocrinology, National Reference Center for Rare Diseases of Insulin Secretion and Insulin Sensitivity, Assistance Publique-Hôpitaux de Paris, Saint-Antoine University Hospital, France. (C.V.).
ORCID: 0000-0002-8181-4721

Classifications MeSH