Macrophage GIT1 promotes oligodendrocyte precursor cell differentiation and remyelination after spinal cord injury.
GIT1
TNFα
macrophage
oligodendrocyte
spinal cord injury
Journal
Glia
ISSN: 1098-1136
Titre abrégé: Glia
Pays: United States
ID NLM: 8806785
Informations de publication
Date de publication:
20 Jun 2024
20 Jun 2024
Historique:
revised:
02
05
2024
received:
29
08
2023
accepted:
27
05
2024
medline:
20
6
2024
pubmed:
20
6
2024
entrez:
20
6
2024
Statut:
aheadofprint
Résumé
Spinal cord injury (SCI) can result in severe motor and sensory deficits, for which currently no effective cure exists. The pathological process underlying this injury is extremely complex and involves many cell types in the central nervous system. In this study, we have uncovered a novel function for macrophage G protein-coupled receptor kinase-interactor 1 (GIT1) in promoting remyelination and functional repair after SCI. Using GIT1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Postgraduate Research & Practice Innovation Program of Jiangsu Province
ID : JX10214014
Organisme : National Key Research and Development Program of China
ID : 2022YFA1205004
Organisme : Young Scholars Fostering Fund of the First Affiliated Hospital of Nanjing Medical University
ID : PY2021012
Organisme : National Natural Science Foundation of China
ID : 8151001184
Organisme : National Natural Science Foundation of China
ID : 81772351
Organisme : National Natural Science Foundation of China
ID : 82030069
Organisme : National Natural Science Foundation of China
ID : 82102570
Organisme : National Natural Science Foundation of China
ID : 82202697
Informations de copyright
© 2024 Wiley Periodicals LLC.
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