Are there double knots in proteins? Prediction and

SPOUT composite knot domain evolution methyltransferase

Journal

Frontiers in molecular biosciences
ISSN: 2296-889X
Titre abrégé: Front Mol Biosci
Pays: Switzerland
ID NLM: 101653173

Informations de publication

Date de publication:
2023
Historique:
received: 16 05 2023
accepted: 04 10 2023
medline: 21 6 2024
pubmed: 21 6 2024
entrez: 21 6 2024
Statut: epublish

Résumé

We have been aware of the existence of knotted proteins for over 30 years-but it is hard to predict what is the most complicated knot that can be formed in proteins. Here, we show new and the most complex knotted topologies recorded to date-double trefoil knots (3

Identifiants

pubmed: 38903539
doi: 10.3389/fmolb.2023.1223830
pii: 1223830
pmc: PMC11187310
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1223830

Informations de copyright

Copyright © 2024 Perlinska, Nguyen, Pilla, Staszor, Lewandowska, Bernat, Purta, Augustyniak, Bujnicki and Sulkowska.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Auteurs

Agata P Perlinska (AP)

Centre of New Technologies, University of Warsaw, Warsaw, Poland.

Mai Lan Nguyen (ML)

Centre of New Technologies, University of Warsaw, Warsaw, Poland.
Polish-Japanese Academy of Information Technology, Warsaw, Poland.

Smita P Pilla (SP)

Centre of New Technologies, University of Warsaw, Warsaw, Poland.

Emilia Staszor (E)

Centre of New Technologies, University of Warsaw, Warsaw, Poland.
Faculty of Chemistry, University of Warsaw, Warsaw, Poland.

Iwona Lewandowska (I)

Centre of New Technologies, University of Warsaw, Warsaw, Poland.

Agata Bernat (A)

Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, Warsaw, Poland.

Elżbieta Purta (E)

Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, Warsaw, Poland.

Rafal Augustyniak (R)

Faculty of Chemistry, University of Warsaw, Warsaw, Poland.

Janusz M Bujnicki (JM)

Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, Warsaw, Poland.

Joanna I Sulkowska (JI)

Centre of New Technologies, University of Warsaw, Warsaw, Poland.

Classifications MeSH