The effects of a brand-specific, hemp-derived cannabidiol product on physiological, biochemical, and psychometric outcomes in healthy adults: a double-blind, randomized clinical trial.


Journal

Journal of the International Society of Sports Nutrition
ISSN: 1550-2783
Titre abrégé: J Int Soc Sports Nutr
Pays: United States
ID NLM: 101234168

Informations de publication

Date de publication:
Dec 2024
Historique:
medline: 21 6 2024
pubmed: 21 6 2024
entrez: 21 6 2024
Statut: ppublish

Résumé

Cannabidiol (CBD) is a non-psychoactive phyto-cannabinoid derived from the 54 healthy males and females (age = 25 ± 7y; BMI = 24.82 ± 3.25 kg/m There were no Group-by-Time interactions or Group or Time main effects for immune or inflammatory biomarkers ( CBD was safe and well tolerated in healthy adults. These findings show pain was lower in the CBD group, suggesting a potentially positive effect for consumption of CBD. "Vigor-activity" decreased across the intervention, which may be a confounding effect of the academic semester. While the dosage chosen was safe, more research may be warranted using higher doses as these may be needed to observe further therapeutic effects in healthy populations.

Sections du résumé

BACKGROUND UNASSIGNED
Cannabidiol (CBD) is a non-psychoactive phyto-cannabinoid derived from the
METHODS UNASSIGNED
54 healthy males and females (age = 25 ± 7y; BMI = 24.82 ± 3.25 kg/m
RESULTS UNASSIGNED
There were no Group-by-Time interactions or Group or Time main effects for immune or inflammatory biomarkers (
DISCUSSION UNASSIGNED
CBD was safe and well tolerated in healthy adults. These findings show pain was lower in the CBD group, suggesting a potentially positive effect for consumption of CBD. "Vigor-activity" decreased across the intervention, which may be a confounding effect of the academic semester. While the dosage chosen was safe, more research may be warranted using higher doses as these may be needed to observe further therapeutic effects in healthy populations.

Identifiants

pubmed: 38904150
doi: 10.1080/15502783.2024.2370430
doi:

Substances chimiques

Cannabidiol 19GBJ60SN5
Biomarkers 0

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Pagination

2370430

Auteurs

Gianna F Mastrofini (GF)

University of South Carolina, Department of Exercise Science, Columbia, SC, USA.

Bridget A McFadden (BA)

City University of New York, Department of Family, Nutrition, and Exercise Science, Queens College, Flushing, NY, USA.

Alexa J Chandler (AJ)

University of South Carolina, Department of Exercise Science, Columbia, SC, USA.

Blaine S Lints (BS)

University of South Carolina, Department of Exercise Science, Columbia, SC, USA.

Harry P Cintineo (HP)

Lindenwood University, Department of Kinesiology, Saint Charles, MO, USA.

Nathaniel D Rhoades (ND)

University of South Carolina, Department of Exercise Science, Columbia, SC, USA.

Caroline S Vincenty (CS)

University of South Carolina, Department of Exercise Science, Columbia, SC, USA.

Sten O Stray-Gundersen (SO)

University of South Carolina, Department of Exercise Science, Columbia, SC, USA.

Abbi D Lane (AD)

University of Michigan, School of Kinesiology, Ann Arbor, MI, USA.

Shawn M Arent (SM)

University of South Carolina, Department of Exercise Science, Columbia, SC, USA.

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Classifications MeSH