The Role of the Microbiome in Allergy, Asthma, and Occupational Lung Disease.
Allergy
Asthma
Exposures
Lung disease
Microbiota
Journal
Current allergy and asthma reports
ISSN: 1534-6315
Titre abrégé: Curr Allergy Asthma Rep
Pays: United States
ID NLM: 101096440
Informations de publication
Date de publication:
21 Jun 2024
21 Jun 2024
Historique:
accepted:
07
06
2024
medline:
21
6
2024
pubmed:
21
6
2024
entrez:
21
6
2024
Statut:
aheadofprint
Résumé
The human commensal microbiota is now widely accepted as a key regulator of human health and disease. The composition of the mucosal associated microbiota has been shown to play a critical role in the lung health. The role of the mucosal microbiota in the development and severity of allergy, asthma, and occupational lung disease is only beginning to take shape. However, advances in our understanding of these links have tremendous potential to led to new clinical interventions to reduce allergy, asthma, and occupational lung disease morbidity. We review recent work describing the relationship and role of the commensal microbiota in the development of allergy, asthma, and occupational lung disease. Our review primarily focuses on occupational exposures and the effects of the microbiome, both in composition and function. Data generated from these studies may lead to the development of interventions targeted at establishing and maintaining a healthy microbiota. We also highlight the role of environmental exposures and the effects on the commensal microbial community and their potential association with occupational lung disease. This review explores the current research describing the role of the human microbiome in the regulation of pulmonary health and disease, with a specific focus on the role of the mucosal microbiota in the development of allergy, asthma, and occupational lung disease.
Identifiants
pubmed: 38904934
doi: 10.1007/s11882-024-01156-8
pii: 10.1007/s11882-024-01156-8
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NIDDK NIH HHS
ID : R01-DK131990-01
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01-DK131990-01
Pays : United States
Organisme : NIAAA NIH HHS
ID : P50-AA030407
Pays : United States
Informations de copyright
© 2024. The Author(s).
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