Severe B12 Deficiency Causing a Maturation Defect Mimicking Myelodysplastic Syndrome With Excess Blasts.
bone marrow biopsy
hypercellular bone marrow
megaloblastic
myelodysplastic syndrome (mds)
myelodysplastic syndrome mimic
severe anemia
severe neutropenia
thrombocytopenia
vit b12 deficiency
“pancytopenia”
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
May 2024
May 2024
Historique:
accepted:
21
05
2024
medline:
24
6
2024
pubmed:
24
6
2024
entrez:
24
6
2024
Statut:
epublish
Résumé
Vitamin B12 deficiency is a common condition that is often asymptomatic, though in severe cases may cause megaloblastic anemia and even neurologic symptoms. Occasionally, the clinical presentation can include pancytopenia and thus mimic a more concerning myelodysplastic syndrome (MDS) until corrected by B12 supplementation. In this unusual case, we present a patient with B12 deficiency who presents with severe macrocytic anemia, neutropenia, lymphocytosis, and a bone marrow morphology consistent with MDS.
Identifiants
pubmed: 38910768
doi: 10.7759/cureus.60837
pmc: PMC11191413
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Pagination
e60837Informations de copyright
Copyright © 2024, Mecham et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.