Prevalence of Obesity-Related Disease in a Danish Population - The Results of an Algorithm-Based Screening Program.

diabetes hypertension metabolic dysfunction-associated steatotic liver disease pre-diabetes sleep apnea

Journal

Diabetes, metabolic syndrome and obesity : targets and therapy
ISSN: 1178-7007
Titre abrégé: Diabetes Metab Syndr Obes
Pays: New Zealand
ID NLM: 101515585

Informations de publication

Date de publication:
2024
Historique:
received: 21 12 2023
accepted: 13 06 2024
medline: 24 6 2024
pubmed: 24 6 2024
entrez: 24 6 2024
Statut: epublish

Résumé

The prevalence of obesity continues to rise. People with obesity are at increased risk of several diseases. We tested an algorithm-based screening program for people with a BMI above 30 kg/m Seven hundred and sixty-nine persons with BMI > 30 kg/m Of those referred, 73.0% were women. We identified new diabetes in 4.2%, prediabetes in 9.1%, moderate-to-severe sleep apnea in 25.1%, increased liver fat and increased liver stiffness in 68.1% and 17.4%, respectively, and hypertension or masked hypertension in 19.0%. The prevalence of diseases was much higher among men and increased with BMI. Except for hypertension, we found few participants with undiagnosed disease in the reference group. An algorithm-based screening program is feasible and reveals undiagnosed obesity-related disease in a large proportion of the participants. The disproportional referral pattern calls for a tailored approach aiming to include more men with obesity. Inclusion of the non-obese group was approved by the Scientific Ethics Committee of The Region of Southern Denmark (project identification number: S-20210091), and the study was reported at clinicaltrials.gov (NCT05176132). The number of people with obesity is going up, and they are at a higher risk for various diseases. We tested a screening program for people referred with a BMI over 30 kg/m

Autres résumés

Type: plain-language-summary (eng)
The number of people with obesity is going up, and they are at a higher risk for various diseases. We tested a screening program for people referred with a BMI over 30 kg/m

Identifiants

pubmed: 38910914
doi: 10.2147/DMSO.S456028
pii: 456028
pmc: PMC11193984
doi:

Banques de données

ClinicalTrials.gov
['NCT05176132']

Types de publication

Journal Article

Langues

eng

Pagination

2505-2517

Informations de copyright

© 2024 Juhl et al.

Déclaration de conflit d'intérêts

The authors report no conflicts of interest in this work.

Auteurs

Claus B Juhl (CB)

Department of Endocrinology, University Hospital of Southern Denmark, Esbjerg, Denmark.
Steno Diabetes Center Odense, University Hospital of Southern Denmark, Odense, Denmark.
University of Southern Denmark, Department of Regional Health Research, Odense, Denmark.
OPEN, Open Patient Data Explorative, Odense University Hospital, Odense, Denmark.

Else Marie Bladbjerg (EM)

University of Southern Denmark, Department of Regional Health Research, Odense, Denmark.
Department of Clinical Biochemistry, University Hospital of Southern Denmark, Esbjerg, Denmark.

Bibi Gram (B)

University of Southern Denmark, Department of Regional Health Research, Odense, Denmark.

Torben Knudsen (T)

University of Southern Denmark, Department of Regional Health Research, Odense, Denmark.
Department of Gastroenterology, University Hospital of Southern Denmark, Esbjerg, Denmark.

Mette Munk Lauridsen (MM)

University of Southern Denmark, Department of Regional Health Research, Odense, Denmark.
Department of Gastroenterology, University Hospital of Southern Denmark, Esbjerg, Denmark.

Niels-Peter Brøchner Nygaard (NB)

Department of Endocrinology, University Hospital of Southern Denmark, Esbjerg, Denmark.
University of Southern Denmark, Department of Regional Health Research, Odense, Denmark.
Department of Neurology, University Hospital of Southern Denmark, Esbjerg, Denmark.

Nina Drøjdahl Ryg (N)

Department of Endocrinology, University Hospital of Southern Denmark, Esbjerg, Denmark.
Steno Diabetes Center Odense, University Hospital of Southern Denmark, Odense, Denmark.
OPEN, Open Patient Data Explorative, Odense University Hospital, Odense, Denmark.

Lars Skadhauge (L)

University of Southern Denmark, Department of Regional Health Research, Odense, Denmark.
Department of Occupational Medicine, University Hospital of Southern Denmark, Esbjerg, Denmark.

Anna-Marie Bloch Münster (AB)

University of Southern Denmark, Department of Regional Health Research, Odense, Denmark.
Department of Clinical Biochemistry, University Hospital of Southern Denmark, Esbjerg, Denmark.

Classifications MeSH