Frankincense: A neuronutrient to approach Parkinson's disease treatment.

Parkinson’s disease antioxidants hormesis vitagenes

Journal

Open medicine (Warsaw, Poland)
ISSN: 2391-5463
Titre abrégé: Open Med (Wars)
Pays: Poland
ID NLM: 101672167

Informations de publication

Date de publication:
2024
Historique:
received: 20 04 2024
revised: 03 06 2024
accepted: 05 06 2024
medline: 24 6 2024
pubmed: 24 6 2024
entrez: 24 6 2024
Statut: epublish

Résumé

Parkinson's disease (PD), characterized by tremor, slowness of movement, stiffness, and poor balance, is due to a significant loss of dopaminergic neurons in the substantia nigra pars compacta and dopaminergic nerve terminals in the striatum with deficit of dopamine. To date the mechanisms sustaining PD pathogenesis are under investigation; however, a solid body of experimental evidence involves neuroinflammation, mitochondrial dysfunction, oxidative stress, and apoptotic cell death as the crucial factors operating in the pathogenesis of PD. Nutrition is known to modulate neuroinflammatory processes implicated in the pathogenesis and progression of this neurodegenerative disorder. Consistent with this notion, the Burseraceae family, which includes the genera

Identifiants

pubmed: 38911256
doi: 10.1515/med-2024-0988
pii: med-2024-0988
pmc: PMC11193358
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

20240988

Informations de copyright

© 2024 the author(s), published by De Gruyter.

Déclaration de conflit d'intérêts

Conflict of interest: Vittorio Calabrese serves as Editor in Chief for Open Medicine, but it did not influenced peer-review process. The authors declare that they have no conflicts of interest.

Auteurs

Vittorio Calabrese (V)

Department of Biomedical and Biotechnological Sciences, University of Catania, Torre Biologica, 95125 Catania, Italy.

Naomi Osakabe (N)

Department of Bioscience and Engineering, Shibaura Institute Technology, Tokyo, Japan.

Foziya Khan (F)

Biodiversity Unit, Dhofar University, Salalah, Oman.

Uwe Wenzel (U)

Institute of Nutritional Science, Justus Liebig University of Giessen, Giessen, Germany.

Sergio Modafferi (S)

Department of Biomedical and Biotechnological Sciences, University of Catania, Torre Biologica, 95125 Catania, Italy.

Lidia Nicolosi (L)

Department of Biomedical and Biotechnological Sciences, University of Catania, Torre Biologica, 95125 Catania, Italy.

Tilman Fritsch (T)

NAM Institute, 5020 Salzburg, Austria.

Ursula M Jacob (UM)

System Biologie AG, Wollerau [CH], Switzerland.

Ali S Abdelhameed (AS)

Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.

Luay Rashan (L)

Biodiversity Unit, Dhofar University, Salalah, Oman.

Classifications MeSH