Effects of silymarin as adjuvant drug on serum levels of CTRP3, anti-cyclic citrullinated peptide (CCP), and high-sensitivity C-reactive protein (hs-CRP) in rheumatoid arthritis patients.
Anti-CCP
CTRP3
Rheumatoid Arthritis
Silymarin
hs-CRP
Journal
Molecular biology research communications
ISSN: 2345-2005
Titre abrégé: Mol Biol Res Commun
Pays: Iran
ID NLM: 101613459
Informations de publication
Date de publication:
2024
2024
Historique:
medline:
25
6
2024
pubmed:
25
6
2024
entrez:
25
6
2024
Statut:
ppublish
Résumé
Silymarin is known for its anti-inflammatory and antioxidant properties. We investigated these effects on serum levels of CTRP3, Anti-CCP, and hs-CRP in individuals with Rheumatoid arthritis (RA). In this study, 42 individuals with RA were recruited and their serum specimens were collected, serum levels of hs-CRP, AntiCCP antibodies, and CTRP3 were measured using ELISA. DNA was extracted and investigated for the existence of possible new mutations in the gene encoding CTRP3 using the PCR technique; the desired fragments were then amplified and sequenced. Another blood sample was collected from the case group after taking
Identifiants
pubmed: 38915456
doi: 10.22099/mbrc.2024.48466.1876
pmc: PMC11194032
doi:
Types de publication
Journal Article
Langues
eng
Pagination
137-145Déclaration de conflit d'intérêts
The authors declare that they have no conflict of interest.