Exploring the Complexities: Understanding the Clinicopathological Spectrum of Tuberculosis in the Head-and-neck Region.
Journal
International journal of mycobacteriology
ISSN: 2212-554X
Titre abrégé: Int J Mycobacteriol
Pays: India
ID NLM: 101615660
Informations de publication
Date de publication:
01 Apr 2024
01 Apr 2024
Historique:
received:
02
04
2024
accepted:
20
05
2024
medline:
25
6
2024
pubmed:
25
6
2024
entrez:
25
6
2024
Statut:
ppublish
Résumé
Tuberculosis (TB) affecting the head-and-neck area can often resemble cancer, leading to misdiagnosis and delayed treatment. A better understanding of this condition is necessary for early diagnosis and prompt treatment initiation. This study examines the clinical and pathological characteristics of different types of TB in the head-and-neck region. This retrospective study analyzed patients diagnosed with TB in the head-and-neck region at a health center between January 1, 2018, and January 1, 2024. The study population consisted of patients who were diagnosed with TB of the head and neck. The study analyzed data from 30 patients, comprising 14 (47%) males and 16 (53%) females, all of whom tested negative for HIV. Most cases (15, 50%) were observed in the age group of 15-24 years, with 5 (15.6%) subjects falling in the age bracket of 0-14 years. Among the types of lesions detected, cervical tubercular adenitis was the most frequently observed lesion, found in 22 (73%) subjects. Females are more susceptible to cervical tubercular adenitis, while males are more likely to experience laryngeal TB. The clinical manifestation of TB affecting the head-and-neck region can exhibit a diverse range of symptoms, which may lead to misinterpretation and diagnostic errors. Therefore, health-care practitioners must understand and include the condition in differential diagnoses.
Identifiants
pubmed: 38916384
doi: 10.4103/ijmy.ijmy_89_24
pii: 01929415-202413020-00005
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
147-151Informations de copyright
Copyright © 2024 Copyright: © 2024 International Journal of Mycobacteriology.
Références
Mannava AS, Wesley Garapati CA, Ganguly S, Jaykar KC. Multifocal cutaneous tuberculosis coexisting with pulmonary tuberculosis. Int J Mycobacteriol 2022;11:329-31.
Aouraghe H, Benchekroun S, Mahraoui C, ElHafidi N. Multifocal tuberculosis in children: A case of spinal tuberculosis. Int J Mycobacteriol 2023;12:204-6.
Kim T, Kim J, Kim T, Oak CH, Ryoo S. Transrenal DNA detection of Mycobacterium tuberculosis in patients with pulmonary tuberculosis. Int J Mycobacteriol 2023;12:66-72.
Ule Belotti NC, Madela NK, Tonelli Nardi SM, Mariano DC, de Souza NG, Oliveira RS, et al. Evaluation of xpert Mycobacterium tuberculosis rifampicin for tuberculosis diagnosis in a reference laboratory. Int J Mycobacteriol 2022;11:435-41.
Setyawan MF, Mertaniasih NM, Soedarsono S, Nuha Z, Maladan Y, Matsumoto S. Mycobacterium tuberculosis – ATPE gene profile of bedaquiline-treated pulmonary tuberculosis patients at the referral hospital Dr. Soetomo, Indonesia. Int J Mycobacteriol 2023;12:122-8.
Sharma N, Khandelwal V, Kumar S, Joshi B, Mohanty KK. Immunological depiction of synthetic B-cell epitopes of Mycobacterium tuberculosis. Int J Mycobacteriol 2023;12:380-7.
Chakaya J, Khan M, Ntoumi F, Aklillu E, Fatima R, Mwaba P, et al. Global tuberculosis report 2020 – Reflections on the global TB burden, treatment and prevention efforts. Int J Infect Dis 2021;113 Suppl 1:S7-12.
Miller T, McNabb S, Hilsenrath P, Pasipanodya J, Weis S, Ahmad S, et al. Global epidemiology of tuberculosis. Semin Respir Crit Care Med 2018;39:271-85.
Shetty D, Vyas D. Combination method for the diagnosis of Tuberculous lymphadenitis in high burden settings. Surgical and Experimental Pathology 2022;5:11.
Aydın O, Bektaş B, Ergen P, Cobanoglu B. Peripheral Lymphadenopathy and Infections: Evaluation of 197 Cases. Ankara Medical Journal 2022;22:434-43.
Aydın Ö, Bektaş B, Ergen P, Cobanoglu B. Peripheral lymphadenopathy and infections: Evaluation of 197 cases. Ankara Med J 2022;22:434-43.
Kakisingi C, Mukuku O, Manika M, Kashal M, Kyabu V, Kasamba E, et al. Peripheral lymphadenopathy: A descriptive study from a tertiary care centre in Lubumbashi (DRC). Open Access Lib J 2016;3:1-9.
Wang Y, Ow TJ, Myers JN. Pathways for cervical metastasis in malignant neoplasms of the head and neck region. Clinical Anatomy 2012;25:54-71.
Purohit MR, Mustafa T, Mørkve O, Sviland L. Gender differences in the clinical diagnosis of tuberculous lymphadenitis – A hospital-based study from Central India. Int J Infect Dis 2009;13:600-5.
Mohapatra PR, Janmeja AK. Tuberculous lymphadenitis. J Assoc Physicians India 2009;57:585-90.
Agarwal AK, Sethi A, Sethi D, Malhotra V, Singal S. Tubercular cervical adenitis: Clinicopathologic analysis of 180 cases. J Otolaryngol Head Neck Surg 2009;38:521-5.
Das S, Das D, Bhuyan UT, Saikia N. Head and neck tuberculosis: Scenario in a tertiary care hospital of North Eastern India. J Clin Diagn Res 2016;10:C04-7.
Arora VK, Gupta R. Trends of extra-pulmonary tuberculosis under revised national tuberculosis control programme: A study from South Delhi. Indian J Tuberc 2006;53:77-83.
Kabra SK, Lodha R, Seth V. Tuberculosis in children – What has changed in last 20 years? Indian J Pediatr 2002;69 Suppl 1:S5-10.
Sharma S, Sarin R, Khalid UK, Singla N, Sharma PP, Behera D. Clinical profile and treatment outcome of tuberculous lymphadenitis in children using DOTS strategy. Indian J Tuberc 2010;57:4-11.
Prasad KC, Sreedharan S, Chakravarthy Y, Prasad SC. Tuberculosis in the head and neck: Experience in India. J Laryngol Otol 2007;121:979-85.
Dandapat MC, Mishra BM, Dash SP, Kar PK. Peripheral lymph node tuberculosis: A review of 80 cases. Br J Surg 1990;77:911-2.
Kheiry J, Ahmed ME. Cervical lymphadenopathy in Khartoum. J Trop Med Hyg 1992;95:416-9.
Dowd CN. III. The surgical treatment of tubercular cervical lymph-nodes: A study of one hundred cases submitted to operation. Ann Surg 1905;42:49-74.
Byrd RB, Bopp RK, Gracey DR, Puritz EM. The role of surgery in tuberculous lymphadenitis in adults. Am Rev Respir Dis 1971;103:816-20.
Jain NK, Bajpai A, Jain S. Outcomes of category III and I in immunocompetent patients of tuberculous lymphadenopathy treated in revised national tuberculosis control programme. Lung India 2010;27:115-7.
Borah P, Deb PK, Venugopala KN, Al-Shar’i NA, Singh V, Deka S, et al. Tuberculosis: An update on pathophysiology, molecular mechanisms of drug resistance, newer anti-TB drugs, treatment regimens and host- directed therapies. Curr Top Med Chem 2021;21:547-70.