Subacute Degeneration of Fibers After Vertical Parasagittal Hemispherotomy.

Diffusion restriction Preoperative hemispheric lesions Vertical parasagittal hemispherotomy Wallerian degeneration

Journal

Clinical neuroradiology
ISSN: 1869-1447
Titre abrégé: Clin Neuroradiol
Pays: Germany
ID NLM: 101526693

Informations de publication

Date de publication:
25 Jun 2024
Historique:
received: 15 01 2024
accepted: 08 05 2024
medline: 26 6 2024
pubmed: 26 6 2024
entrez: 25 6 2024
Statut: aheadofprint

Résumé

After vertical parasagittal hemispherotomy a restricted diffusion is often seen ipsilaterally and even distant from the adjacent resection margin. This retrospective cohort study analyses the anatomic site and the time course of the diffusion restriction after vertical parasagittal hemispherotomy. Fifty-nine patients were included into this study, all of them having had one pre-operative and at least one post-operative MRI, including diffusion imaging at b‑values of 0 and 1000 s/mm Diffusion restriction occurred exclusively on the operated site in all patients. In the basal ganglia, diffusion restriction was present in 37 of 38 patients at the first postoperative day with a duration of 38 days. In the midbrain, the posterior limb of the internal capsule and the thalamus, a restricted diffusion became postoperatively prominent at day 9 in all three localizations, with a duration of 36, 34 and 36 days, respectively. The incidence of thalamic lesions was lower if a preoperative damage had occurred. The restricted diffusion in the basal ganglia resembles direct effects of the operation at its edges, whereas the later appearing diffusion restriction in the midbrain and the posterior limb of the internal capsule rather belong to a degeneration of the descending fibers being transected by the hemispherotomy in the sense of a Wallerian degeneration. The presence of preoperative hemispheric lesions influences the development of diffusion restriction at subacute fiber degeneration.

Identifiants

pubmed: 38918242
doi: 10.1007/s00062-024-01427-x
pii: 10.1007/s00062-024-01427-x
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s).

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Auteurs

Markus Hittinger (M)

Specialist Centre for Radiology, Schoen Clinic Vogtareuth, Vogtareuth, Germany. Markus.Hittinger@uk-augsburg.de.
Clinic for Diagnostic and Interventional Radiology and Neuroradiology, University Medical Centre, Augsburg, Germany. Markus.Hittinger@uk-augsburg.de.

Till Hartlieb (T)

Specialist Centre for Paediatric Neurology, Neurorehabilitation and Epileptology, Schoen Clinic Vogtareuth, Vogtareuth, Germany.

Dieter Henrik Heiland (DH)

Clinic for Neurosurgery, University Medical Centre, Freiburg, Germany.
Department of Neurosurgery, Medical Centre-University of Freiburg, Freiburg im Breisgau, Germany.
Department of Neurosurgery, University Hospital Erlangen, Erlangen, Germany.

Pamela Heiland (P)

Department of Neurosurgery, University Hospital Erlangen, Erlangen, Germany.

Tom Pieper (T)

Specialist Centre for Paediatric Neurology, Neurorehabilitation and Epileptology, Schoen Clinic Vogtareuth, Vogtareuth, Germany.

Martin Staudt (M)

Specialist Centre for Paediatric Neurology, Neurorehabilitation and Epileptology, Schoen Clinic Vogtareuth, Vogtareuth, Germany.
Centre for Paediatric Palliative Care, Ludwig Maximilian University of Munich, Munich, Germany.

Ansgar Berlis (A)

Specialist Centre for Radiology, Schoen Clinic Vogtareuth, Vogtareuth, Germany.
Clinic for Diagnostic and Interventional Radiology and Neuroradiology, University Medical Centre, Augsburg, Germany.

Manfred Kudernatsch (M)

Specialist Centre for Neurosurgery and Epilepsy Surgery, Schoen Clinic Vogtareuth, Vogtareuth, Germany.

Irina Mader (I)

Specialist Centre for Radiology, Schoen Clinic Vogtareuth, Vogtareuth, Germany.
University Children's Hospital, Basel, Switzerland.
Department of Neurosurgery, Medical Centre-University of Freiburg, Freiburg im Breisgau, Germany.

Classifications MeSH