Hodgkin lymphoma: hypodense lesions in mediastinal masses.

Humans Male Female Hodgkin Disease / pathology Adult Mediastinal Neoplasms / pathology Middle Aged Tomography, X-Ray Computed Young Adult Aged Adolescent Mediastinum / pathology Fluorodeoxyglucose F18 Positron-Emission Tomography Progression-Free Survival

Hodgkin lymphoma Hypodense lesion Thymic cyst Tomography X-ray computed

Journal

Scientific reports

ISSN: 2045-2322

Titre abrégé: Sci Rep

Pays: England

ID NLM: 101563288

Informations de publication

Date de publication:
25 06 2024

Historique:

received: 18 08 2023

accepted: 06 06 2024

medline: 26 6 2024

pubmed: 26 6 2024

entrez: 25 6 2024

Statut: epublish

Résumé

Hypodense volumes (HDV) in mediastinal masses can be visualized in a computed tomography scan in Hodgkin lymphoma. We analyzed staging CT scans of 1178 patients with mediastinal involvement from the EuroNet-PHL-C1 trial and explored correlations of HDV with patient characteristics, mediastinal tumor volume and progression-free survival. HDV occurred in 350 of 1178 patients (29.7%), typically in larger mediastinal volumes. There were different patterns in appearance with single lesions found in 243 patients (69.4%), multiple lesions in 107 patients (30.6%). Well delineated lesions were found in 248 cases (70.1%), diffuse lesions were seen in 102 cases (29.1%). Clinically, B symptoms occurred more often in patients with HDV (47.7% compared to 35.0% without HDV (p = 0.039)) and patients with HDV tended to be in higher risk groups. Inadequate overall early-

Identifiants

DOI: 10.1038/s41598-024-64253-8 PMID: 38918503

pubmed: 38918503

doi: 10.1038/s41598-024-64253-8

pii: 10.1038/s41598-024-64253-8

doi:

Substances chimiques

Fluorodeoxyglucose F18 0Z5B2CJX4D

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

Pagination

14591

Informations de copyright

Références

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