Physical activity and exercise health benefits: cancer prevention, interception, and survival.
Journal
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)
ISSN: 1473-5709
Titre abrégé: Eur J Cancer Prev
Pays: England
ID NLM: 9300837
Informations de publication
Date de publication:
26 Jun 2024
26 Jun 2024
Historique:
medline:
26
6
2024
pubmed:
26
6
2024
entrez:
26
6
2024
Statut:
aheadofprint
Résumé
Physical activity (PA) has an established role in the promotion of health and fitness and the prevention of disease. Expected overall benefits include reduction of all-cause morbidity and death, weight control, improved quality of life, improved bone health and decreased falls of elderly subjects, , deeper cognition, and reduced risk of depression, anxiety, and sleeplessness. Currently, PA is a mainstay in the management of cardiovascular diseases, metabolic syndrome, diabetes, and bone health. Recently, the perception of its role in primary and secondary prevention, interception, and treatment of cancer, however, is also gaining importance. Regular walking, the simplest type of PA, is associated with reduced all-cause and cardiovascular disease mortality, and a role in cancer prevention is of increasing interest. Furthermore, PA improves the quality of life of cancer patients, attenuating side effects of chemotherapy, decreasing sarcopenia, increasing fitness, and inhibiting the recurrence and progression of some cancer types. It promotes emotional and psychological benefits in patients, inducing positive changes. While mechanisms, effective levels and useful amount of PA practice are well established in cardiology, they are yet to be fully determined in oncology. Nevertheless, PA is recommended to reduce cancer risk in the general population, and it has been introduced in programs for the prevention of second cancers. In perspective, it will help as integrative therapy in cancer patients and for cancer survivors. The number of beneficial effects in the cancer continuum is highlighted in this review.
Identifiants
pubmed: 38920329
doi: 10.1097/CEJ.0000000000000898
pii: 00008469-990000000-00152
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.
Références
Albini A, Cavuto S, Apolone G, Noonan DM (2015). Strategies to prevent ‘bad luck’ in cancer. J Natl Cancer Inst 107:djv213.
Albini A, DeCensi A, Cavalli F, Costa A (2016). Cancer prevention and interception: a new era for chemopreventive approaches. Clin Cancer Res 22:4322–4327.
Aldhahi MI, Baattaiah BA, Alharbi MD, Alotaibi M, Nazer R, Albarrati A (2024). Multifaceted associations between walking performance, physical fitness, extremity function, health status, and depression in individuals with COPD. Ann Med 56:2338248.
Almuqahwi A, Alabdrabulridha H, Aljumaiah RM, Alfaifi AJ, Alnaim MF, Alfaifi IA, et al. (2023). A systematic review on the relationship between physical activity and sexual function in adults. Cureus 15:e51307.
American Diabetes Association (2018). Lifestyle management: standards of medical care in diabetes-2018. Diabetes Care 41:S38–S50.
Amin AM, Khlidj Y, Abuelazm M, Ibrahim AA, Tanashat M, Imran M, et al. (2024). The efficacy cardiotoxicity: a systematic review and meta-analysis of randomized and safety of exercise regimens to mitigate chemotherapy controlled trials. Cardiooncology 10:10.
Anazco D, Acosta A, Cathcart-Rake EJ, D’Andre SD, Hurtado MD (2024). Weight-centric prevention of cancer. Obes Pillars 10:100106.
Anish RJ, Nair A (2024). Osteoporosis management-current and future perspectives - a systemic review. J Orthop 53:101–113.
Argilés JM, Busquets S, López-Soriano FJ, Costelli P, Penna F (2012). Are there any benefits of exercise training in cancer cachexia? J Cachexia Sarcopenia Muscle 3:73–76.
Aune D, Norat T, Leitzmann M, Tonstad S, Vatten LJ (2015). Physical activity and the risk of type 2 diabetes: a systematic review and dose-response meta-analysis. Eur J Epidemiol 30:529–542.
Banach M, Lewek J, Surma S, Penson PE, Sahebkar A, Martin SS, et al. (2023). The association between daily step count and all-cause and cardiovascular mortality: a meta-analysis. Eur J Prev Cardiol 30:1975–1985.
Baumann FT, Jensen W, Berling-Ernst A, Theurich S, Leitzmann M, Götte M (2024). Exercise therapy in oncology—the impact on quality of life and side effects. Dtsch Arztebl Int doi: 10.3238/arztebl.m2024.0038.
doi: 10.3238/arztebl.m2024.0038
Beg MS, Gupta A, Stewart T, Rethorst CD (2017). Promise of wearable physical activity monitors in oncology practice. J Oncol Pract 13:82–89.
Bellissimo MP, Canada JM, Jordan JH, Ladd AC, Reding KW, Moore TL, et al.; UPBEAT Study Group (2023). Physical activity during breast cancer therapy associates with preserved exercise capacity and cardiac function (WF97415). JACC CardioOncol 5:641–652.
Bird SR, Hawley JA (2017). Update on the effects of physical activity on insulin sensitivity in humans. BMJ Open Sport Exerc Med 2:e000143.
de Boer W, Corpeleijn E, Dekker L, Mierau J, Koning R (2021). How is sport participation related to mortality, diabetes and prediabetes for different body mass index levels? Scand J Med Sci Sports 31:1342–1351.
Bonekamp NE, Visseren FLJ, Cramer MJ, Dorresteijn JAN, van der Meer MG, Ruigrok YM, et al. (2024). Long-term lifestyle change and risk of mortality and type 2 diabetes in patients with cardiovascular disease. Eur J Prev Cardiol 31:205–213.
de Boniface J, Altena R, Haddad Ringborg C, Bolam KA, Wengström Y (2022). Physical exercise during neoadjuvant chemotherapy for breast cancer as a mean to increase pathological complete response rates: trial protocol of the randomized Neo-ACT trial. PLoS One 17:e0274804.
Bonnet F, Irving K, Terra JL, Nony P, Berthezène F, Moulin P (2005). Anxiety and depression are associated with unhealthy lifestyle in patients at risk of cardiovascular disease. Atherosclerosis 178:339–344.
Brittain EL, Han L, Annis J, Master H, Hughes A, Roden DM, et al. (2024). Physical activity and incident obesity across the spectrum of genetic risk for obesity. JAMA Netw Open 7:e243821.
Brown JC, Ma C, Shi Q, Niedzwiecki D, Zemla T, Couture F, et al. (2023). Association between physical activity and the time course of cancer recurrence in stage III colon cancer. Br J Sports Med 57:965–971.
Cailleaux PE, Déchelotte P, Coëffier M (2024). Novel dietary strategies to manage sarcopenia. Curr Opin Clin Nutr Metab Care 27:234–243.
Campbell K, Winters-Stone KM, Wiskemann J, May AM, Schwartz AL, Courneya KS, et al. (2019). Exercise guidelines for cancer survivors: consensus statement from International Multidisciplinary Roundtable. Med Sci Sports Exerc 51:2375–2390.
Caspersen CJ, Powell KE, Christenson GM (1985). Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research. Public Health Rep 100:126–131.
Ceci C, García-Chico C, Atzori MG, Lacal PM, Lista S, Santos-Lozano A, et al. (2024). Impact of physical exercise on melanoma hallmarks: current status of preclinical and clinical research. J Cancer 15:1–19.
Chen X, Li J, Chen C, Zhang Y, Zhang S, Zhang Y, et al. (2023). Effects of exercise interventions on cancer-related fatigue and quality of life among cancer patients: a meta-analysis. BMC Nurs 22:200.
Chen F, Lin C, Gu X, Ning Y, He H, Qiang G (2024). Exploring the link between walking and lung cancer risk: a two-stage Mendelian randomization analysis. BMC Pulm Med 24:129.
Chiang CH, Chang YC, Haw Y, Tan JY, Chiang CH, Hsia YP, et al. (2023). The Effect of Exercise on Cardiotoxicity in Women with Breast Cancer Receiving Anthracycline-based chemotherapy: A Systematic Review and Meta-analysis. Oncology doi: 10.1159/000535737
doi: 10.1159/000535737
Ciernikova S, Sevcikova A, Stevurkova V, Mego M (2023). Diet-driven microbiome changes and physical activity in cancer patients. Front Nutr 10:1285516.
Corso G, Janssens JP, La Vecchia C (2023). Cancer prevention: innovative strategies in the role of the European Cancer Prevention Organization. Eur J Cancer Prev 32:203–206.
Cuff DJ, Meneilly GS, Martin A, Ignaszewski A, Tildesley HD, Frohlich JJ (2003). Effective exercise modality to reduce insulin resistance in women with type 2 diabetes. Diabetes Care 26:2977–2982.
Diao X, Ling Y, Zeng Y, Wu Y, Guo C, Jin Y, et al. (2023). Physical activity and cancer risk: a dose-response analysis for the Global Burden of Disease Study 2019. Cancer Commun (Lond) 43:1229–1243.
Dixon-Suen SC, Lewis SJ, Martin RM, English DR, Boyle T, Giles GG, et al.; Breast Cancer Association Consortium (2022). Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study. Br J Sports Med 56:1157–1170.
Duan X, Liu R, Xi Y, Tian Z (2024). The mechanisms of exercise improving cardiovascular function by stimulating Piezo1 and TRP ion channels: a systemic review. Mol Cell Biochem doi: 10.1007/s11010-024-05000-5.
doi: 10.1007/s11010-024-05000-5
Dunston ER, Mulibea PB, Chipman J, Zickmund S, Oza S, Zingg RW, et al. (2023). Factors influencing engagement in hospital-based exercise oncology programs: a narrative review. PM R 15:916–924.
Erdik A, Cimen HI, Atik YT, Gul D, Kose O, Halis F, et al. (2023). Sarcopenia is an independent predictor of survival in patients undergoing radical cystectomy for bladder cancer: a single-centre, retrospective study. Cent European J Urol 76:81–89.
Fabi A, Rossi A, Mocini E, Cardinali L, Bonavolontà V, Cenci C, et al. (2024). An integrated care approach to improve well-being in breast cancer patients. Curr Oncol Rep 26:346–358.
Fang X, Zhang X, Yang Z, Yu L, Lin K, Chen T, et al. (2024). Healthy lifestyles and rapid progression of carotid plaque in population with atherosclerosis: a prospective cohort study in China. Prev Med Rep 41:102697.
Fleg JL (2016). Healthy lifestyle and risk of heart failure: an ounce of prevention well worth the effort. Circ Heart Fail 9:e003155.
Fleg JL, Cooper LS, Borlaug BA, Haykowsky MJ, Kraus WE, Levine BD, et al.; National Heart, Lung, and Blood Institute Working Group (2015). Exercise training as therapy for heart failure: current status and future directions. Circ Heart Fail 8:209–220.
Francois ME, Baldi JC, Manning PJ, Lucas SJ, Hawley JA, Williams MJ, et al. (2014). ‘Exercise snacks’ before meals: a novel strategy to improve glycaemic control in individuals with insulin resistance. Diabetologia 57:1437–1445.
Frick C, Rumgay H, Vignat J, Ginsburg O, Nolte E, Bray F, et al. (2023). Quantitative estimates of preventable and treatable deaths from 36 cancers worldwide: a population-based study. Lancet Glob Health 11:e1700–e1712.
Fukushima N, Kikuchi H, Sato H, Sasai H, Kiyohara K, Sawada SS, et al. (2024). Dose-response relationship of physical activity with all-cause mortality among older adults: an umbrella review. J Am Med Dir Assoc 25:417–430.
Garber CE, Blissmer B, Deschenes MR, Franklin BA, Lamonte MJ, Lee IM, et al.; American College of Sports Medicine (2011). American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Med Sci Sports Exerc 43:1334–1359.
García-Chico C, López-Ortiz S, Peñín-Grandes S, Pinto-Fraga J, Valenzuela PL, Emanuele E, et al. (2023). Physical exercise and the hallmarks of breast cancer: a narrative review. Cancers (Basel) 15:324.
Garrone O, Paccagnella M, Ruatta F, Gallo C, Rivoltini L, Merlano MC (2021). Moderate physical activity (MPA) modulates immune system in breast cancer (BC) patients during preoperative chemotherapy: the NEO-RUNNER study. Ann Oncol 32:S429.
Garrone O, Paccagnella M, Abbona A, Ruatta F, Vanella P, Tomasello G, et al. (2023). Moderate physical exercise and immune system modulation in patients with breast cancer treated with neoadjuvant chemotherapy. J Clin Oncol 41:605–605.
GBD 2016 Causes of Death Collaborators, (2017). Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet 390:1151–1210.
Gillies CL, Abrams KR, Lambert PC, Cooper NJ, Sutton AJ, Hsu RT, et al. (2007). Pharmacological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance: systematic review and meta-analysis. BMJ 334:299.
Gnagnarella P, Dragà D, Raja S, Baggi F, Simoncini MC, Sabbatini A, et al. (2023). Physical activity and/or dietary intervention in overweight or obese breast cancer survivors: results of the InForma randomized trial. J Cancer Surviv doi: 10.1007/s11764-023-01415-z.
doi: 10.1007/s11764-023-01415-z
Hackney AC, Lane AR (2015). Exercise and the regulation of endocrine hormones. Prog Mol Biol Transl Sci 135:293–311.
Herazo-Beltrán Y, Pinillos Y, Vidarte J, Crissien E, Suarez D, García R (2017). Predictors of perceived barriers to physical activity in the general adult population: a cross-sectional study. Braz J Phys Ther 21:44–50.
Huang Z, Zhuang X, Huang R, Liu M, Xu X, Fan Z, et al. (2024). Physical activity and weight loss among adults with type 2 diabetes and overweight or obesity: a post hoc analysis of the look AHEAD trial. JAMA Netw Open 7:e240219.
Hussain N, Gersh BJ, Gonzalez Carta K, Sydo N, Lopez-Jimenez F, Kopecky SL, et al. (2018). Impact of cardiorespiratory fitness on frequency of atrial fibrillation, stroke, and all-cause mortality. Am J Cardiol 121:41–49.
International Agency for Research on Cancer (2024). Population factsheet. https://gco.iarc.fr/today/en/fact-sheets-populations
Iyengar NM, Jones LW (2019). Development of exercise as interception therapy for cancer: a review. JAMA Oncol 5:1620–1627.
Jenkins DG, Devin JL, Weston KL, Jenkins JG, Skinner TL (2023). Benefits beyond cardiometabolic health: the potential of frequent high intensity ‘exercise snacks’ to improve outcomes for those living with and beyond cancer. J Physiol 601:4691–4697.
Jones LW, Fels DR, West M, Allen JD, Broadwater G, Barry WT, et al. (2013). Modulation of circulating angiogenic factors and tumor biology by aerobic training in breast cancer patients receiving neoadjuvant chemotherapy. Cancer Prev Res (Phila) 6:925–937.
Khadanga S, Beebe-Peat T (2024). Optimal medical therapy for stable ischemic heart disease in 2024: focus on exercise and cardiac rehabilitation. Med Clin North Am 108:509–516.
Kitajima K, Oiwa A, Miyakoshi T, Hosokawa M, Furihata M, Takahashi M, et al. (2023). Interval walking training in type 2 diabetes: a pilot study to evaluate the applicability as exercise therapy. PLoS One 18:e0285762.
Koelwyn GJ, Quail DF, Zhang X, White RM, Jones LW (2017). Exercise-dependent regulation of the tumour microenvironment. Nat Rev Cancer 17:620–632.
Koh YS, Asharani PV, Devi F, Roystonn K, Wang P, Vaingankar JA, et al. (2022). A cross-sectional study on the perceived barriers to physical activity and their associations with domain-specific physical activity and sedentary behaviour. BMC Public Health 22:1051.
Koivula T, Lempiäinen S, Rinne P, Rannikko JH, Hollmén M, Sundberg CJ, et al. (2023). The effect of acute exercise on circulating immune cells in newly diagnosed breast cancer patients. Sci Rep 13:6561.
Kouidi E, Hanssen H, Anding-Rost K, Cupisti A, Deligiannis A, Grupp C, et al. (2024). The role of exercise training on cardiovascular risk factors and heart disease in patients with chronic kidney disease G3-G5 and G5D: a clinical consensus statement of the European Association of Preventive Cardiology (EAPC) of the ESC and the European Association of Rehabilitation in Chronic Kidney Disease (EURORECKD). Eur J Prev Cardiol doi: 10.1093/eurjpc/zwae130.
doi: 10.1093/eurjpc/zwae130
Kyu HH, Bachman VF, Alexander LT, Mumford JE, Afshin A, Estep K, et al. (2016). Physical activity and risk of breast cancer, colon cancer, diabetes, ischemic heart disease, and ischemic stroke events: systematic review and dose-response meta-analysis for the Global Burden of Disease Study 2013. BMJ 354:i3857.
Lavín-Pérez AM, Collado-Mateo D, Abbasi S, Ferreira-Júnior JB, Hekmatikar AHA (2023). Effects of exercise on immune cells with tumor-specific activity in breast cancer patients and survivors: a systematic review and meta-analysis. Support Care Cancer 31:507.
Lee Y, Park S, Park S, Kwon HJ, Lee SH, Kim Y, et al. (2024). Exercise affects high-fat diet-stimulated breast cancer metastasis through irisin secretion by altering cancer stem cell properties. Biochem Biophys Rep 38:101684.
Leung WK, Yau SY, Yang Y, Kwok AW, Wong EM, Cheung JK, et al. (2024). Effects of exercise interventions on brain-derived neurotrophic factor levels in overweight and obesity: a systematic review and meta-analysis. J Exerc Sci Fit 22:278–287.
Li C, Powell L, Stamatakis E, McGreevy P, Podberscek A, Bauman A, et al. (2024). Is dog walking suitable for physical activity promotion? Investigating the exercise intensity of on-leash dog walking. Prev Med Rep 41:102715.
Ligibel JA, Dillon D, Giobbie-Hurder A, McTiernan A, Frank E, Cornwell M, et al. (2019). Impact of a pre-operative exercise intervention on breast cancer proliferation and gene expression: results from the pre-operative health and body (PreHAB) study. Clin Cancer Res 25:5398–5406.
Ligibel JA, Bohlke K, May AM, Clinton SK, Demark-Wahnefried W, Gilchrist SC, et al. (2022). Exercise, diet, and weight management during cancer treatment: ASCO guideline. J Clin Oncol 40:2491–2507.
Lim WA, June CH (2017). The principles of engineering immune cells to treat cancer. Cell 168:724–740.
Liu AI, Lee YH, Lu CY, Huda N, Huang TW (2023). Effects of walking combined with resistance band exercises on alleviating cancer-related fatigue: a systematic review and meta-analysis of randomized controlled trials. Cancer Nurs doi: 10.1097/NCC.0000000000001300.
doi: 10.1097/NCC.0000000000001300
Locasale JW, Goncalves MD, Di Tano M, Burgos-Barragan G (2024). Diet and cancer metabolism. Cold Spring Harb Perspect Med :a041549. doi: 10.1101/cshperspect.a041549.
doi: 10.1101/cshperspect.a041549
Lönnberg L, Ekblom-Bak E, Damberg M (2019). Improved unhealthy lifestyle habits in patients with high cardiovascular risk: results from a structured lifestyle programme in primary care. Ups J Med Sci 124:94–104.
Lu Y, Bai X, Pan C (2024). Impact of exercise interventions on quality of life and depression in lung cancer patients: a systematic review and meta-analysis. Int J Psychiatry Med 59:199–217.
Lyu DW (2024). Immunomodulatory effects of exercise in cancer prevention and adjuvant therapy: a narrative review. Front Physiol 14:1292580.
Mali SB (2024). Role of telemedicine in head neck cancer. Oral Oncol 151:106746.
Malveiro C, Correia IR, Cargaleiro C, Magalhães JP, de Matos LV, Hilário S, et al. (2023). Effects of exercise training on cancer patients undergoing neoadjuvant treatment: a systematic review. J Sci Med Sport 26:586–592.
Mandsager K, Harb S, Cremer P, Phelan D, Nissen SE, Jaber W (2018). Association of cardiorespiratory fitness with long-term mortality among adults undergoing exercise treadmill testing. JAMA Netw Open 1:e183605.
Masiero M, Filipponi C, Fragale E, Pizzoli SFM, Munzone E, Milani A, et al. (2024). Support for chronic pain management for breast cancer survivors through novel digital health ecosystems: pilot usability study of the PainRELife mobile app. JMIR Form Res 8:e51021.
Mast IH, Bongers CCWG, Gootjes EC, de Wilt JHW, Hopman MTE, Buffart LM (2024). Potential mechanisms underlying the effect of walking exercise on cancer-related fatigue in cancer survivors. J Cancer Surviv doi: 10.1007/s11764-024-01537-y.
doi: 10.1007/s11764-024-01537-y
Matthews CE, Moore SC, Arem H, Cook MB, Trabert B, Håkansson N, et al. (2020). Amount and intensity of leisure-time physical activity and lower cancer risk. J Clin Oncol 38:686–697.
Mendes R, Dias E, Gama A, Castelo-Branco M, Themudo-Barata JL (2013). Exercise practice and habitual physical activity levels in patients with type 2 diabetes: a pilot study in Portugal. Rev Port Endocrinol Diabetes Metab 8:9–15.
Mölenberg FJM, Panter J, Burdorf A, van Lenthe FJ (2019). A systematic review of the effect of infrastructural interventions to promote cycling: strengthening causal inference from observational data. Int J Behav Nutr Phys Act 16:93.
Moore SC, Patel AV, Matthews CE, Berrington de Gonzalez A, Park Y, Katki HA, et al. (2012). Leisure time physical activity of moderate to vigorous intensity and mortality: a large pooled cohort analysis. PLoS Med 9:e1001335.
Ning Y, Dong Z, Jia Z, Zhao W, Ding Y, Wang Q, et al. (2023). Development of mobile health-based interventions to promote physical activity in patients with head and neck cancer: a qualitative study. Front Public Health 11:1260804.
Nyrop KA, Page A, Deal AM, Wagoner C, Kelly EA, Kimmick GG, et al. (2023). Association of self-directed walking with toxicity moderation during chemotherapy for the treatment of early breast cancer. Support Care Cancer 32:68.
Orange ST, Leslie J, Ross M, Mann DA, Wackerhage H (2023). The exercise IL-6 enigma in cancer. Trends Endocrinol Metab 34:749–763.
Parvanova I, Finkelstein J (2024). Towards a patient-centered design of a cancer telerehabilitation system. Stud Health Technol Inform 310:1569–1573.
Patel AV, Friedenreich CM, Moore SC, Hayes SC, Silver JK, Campbell KL, et al. (2019). American College of Sports Medicine Roundtable Report on physical activity, sedentary behavior, and cancer prevention and control. Med Sci Sports Exerc 51:2391–2402.
Patterson R, McNamara E, Tainio M, de Sá TH, Smith AD, Sharp SJ, et al. (2018). Sedentary behaviour and risk of all-cause, cardiovascular and cancer mortality, and incident type 2 diabetes: a systematic review and dose response meta-analysis. Eur J Epidemiol 33:811–829.
Pelliccia A, Sharma S, Gati S, Bäck M, Börjesson M, Caselli S, et al.; ESC Scientific Document Group (2021). 2020 ESC Guidelines on sports cardiology and exercise in patients with cardiovascular disease. Eur Heart J 42:17–96.
Peng W, Bai X, Yang Y, Cui J, Xu W, Song L, et al. (2024). Healthy lifestyle, statin, and mortality in people with high CVD risk: a nationwide population-based cohort study. Am J Prev Cardiol 17:100635.
Physical Activity Guidelines Advisory Committee. (2018). Physical Activity Guidelines Advisory Committee Scientific Report. Services DoHaH.
Piepoli MF, Conraads V, Corrà U, Dickstein K, Francis DP, Jaarsma T, et al. (2011). Exercise training in heart failure: from theory to practice. A consensus document of the Heart Failure Association and the European Association for Cardiovascular Prevention and Rehabilitation. Eur J Heart Fail 13:347–357.
Piepoli MF, Hoes AW, Agewall S, Albus C, Brotons C, Catapano AL, et al.; ESC Scientific Document Group (2016). 2016 European Guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts) Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR). Eur Heart J 37:2315–2381.
Powers-James C, Morse M, Narayanan S, Ramondetta L, Lopez G, Wagner R, et al. (2024). Integrative oncology approaches to reduce recurrence of disease and improve survival. Curr Oncol Rep 26:147–163.
Puklin LS, Ferrucci LM, Harrigan M, McGowan C, Zupa M, Cartmel B, et al. (2024). Improving lifestyle behaviors during chemotherapy for breast cancer: the lifestyle, exercise, and nutrition early after diagnosis (LEANer) trial. Cancer doi: 10.1002/cncr.35280.
doi: 10.1002/cncr.35280
Qi Z, Zheng Y, Chan JSK, Tse G, Liu T (2024). Exercise-based cardiac rehabilitation for left ventricular function in patients with heart failure: a systematic review and meta-analysis. Curr Probl Cardiol 49:102210.
Ranes M, Wiestad TH, Thormodsen I, Arving C (2022). Determinants of exercise adherence and maintenance for cancer survivors: implementation of a community-based group exercise program. A qualitative feasibility study. PEC Innov 1:100088.
Ren X, Hu C, Wang W, He Q, Du L, Li T, et al. (2024). Association between physical activity, sedentary behavior patterns with bone health among Chinese older women. Bone 181:117025.
Rock CL, Thomson C, Gansler T, Gapstur SM, McCullough ML, Patel AV, et al. (2020). American Cancer Society guideline for diet and physical activity for cancer prevention. CA Cancer J Clin 70:245–271.
Rock CL, Thomson CA, Sullivan KR, Howe CL, Kushi LH, Caan BJ, et al. (2022). American Cancer Society nutrition and physical activity guideline for cancer survivors. CA Cancer J Clin 72:230–262.
Rogers LQ, Courneya KS, Oster RA, Anton PM, Phillips S, Ehlers DK, et al. (2023). Physical activity intervention benefits persist months post-intervention: randomized trial in breast cancer survivors. J Cancer Surviv 17:1834–1846.
Saint-Maurice PF, Troiano RP, Bassett DR Jr, Graubard BI, Carlson SA, Shiroma EJ, et al. (2020). Association of daily step count and step intensity with mortality among US adults. JAMA 323:1151–1160.
Sanft T, Harrigan M, McGowan C, Cartmel B, Zupa M, Li FY, et al. (2023). Randomized trial of exercise and nutrition on chemotherapy completion and pathologic complete response in women with breast cancer: the lifestyle, exercise, and nutrition early after diagnosis study. J Clin Oncol 41:5285–5295.
Santagnello SB, Martins FM, de Oliveira Junior GN, de Freitas Rodrigues de Sousa J, Nomelini RS, Murta EFC, et al. (2020). Improvements in muscle strength, power, and size and self-reported fatigue as mediators of the effect of resistance exercise on physical performance breast cancer survivor women: a randomized controlled trial. Support Care Cancer 28:6075–6084.
Santagnello SB, Martins FM, de Oliveira Junior GN, de Sousa JFR, Nomelini RS, Murta EFC, et al. (2024). Resistance Training-Induced Gains in Muscle Strength and Power Mediate the Improvement in Walking Speed in Middle-Aged Women Who Are Breast Cancer Survivors. J Strength Cond Res 38:773–782.
Sattelmair J, Pertman J, Ding EL, Kohl HW 3rd, Haskell W, Lee IM (2011). Dose response between physical activity risk of coronary heart disease: a meta-analysis. Circulation 124:789–795.
Savvakis I, Adamakidou T, Kleisiaris C (2024). Physical-activity interventions to reduce fear of falling in frail and pre-frail older adults: a systematic review of randomized controlled trials. Eur Geriatr Med 15:333–344.
Schadler KL, Thomas NJ, Galie PA, Bhang DH, Roby KC, Addai P, et al. (2016). Tumor vessel normalization after aerobic exercise enhances chemotherapeutic efficacy. Oncotarget 7:65429–65440.
Schmitz KH, Campbell AM, Stuiver MM, Pinto BM, Schwartz AL, Morris GS, et al. (2019). Exercise is medicine in oncology: engaging clinicians to help patients move through cancer. CA Cancer J Clin 69:468–484.
Sebri V, Durosini I, Mazzoni D, Pravettoni G (2022). Breast cancer survivors’ motivation to participate in a tailored physical and psychological intervention: a qualitative thematic analysis. Behav Sci (Basel) 12:271.
SenthilKumar G, Schottstaedt AM, Peterson LL, Pedersen LN, Chitambar CR, Vistocky A, et al. (2024). Stay on track: a pilot randomized control trial on the feasibility of a diet and exercise intervention in patients with breast cancer receiving radiation therapy. Cancer Res Commun 4:1211–1226.
Smith AD, Crippa A, Woodcock J, Brage S (2016). Physical activity and incident type 2 diabetes mellitus: a systematic review and dose-response meta-analysis of prospective cohort studies. Diabetologia 59:2527–2545.
Spanoudaki M, Giaginis C, Karafyllaki D, Papadopoulos K, Solovos E, Antasouras G, et al. (2023). Exercise as a promising agent against cancer: evaluating its anti-cancer molecular mechanisms. Cancers (Basel) 15:5135.
Strain T, Dempsey PC, Wijndaele K, Sharp SJ, Kerrison N, Gonzales TI, et al. (2023). Quantifying the relationship between physical activity energy expenditure and incident type 2 diabetes: a prospective cohort study of device-measured activity in 90,096 adults. Diabetes Care 46:1145–1155.
Strathearn LS, Stepanov AI, Font-Burgada J (2020). Inflammation in primary and metastatic liver tumorigenesis-under the influence of alcohol and high-fat diets. Nutrients 12:933.
Stringhini S, Sabia S, Shipley M, Brunner E, Nabi H, Kivimaki M, et al. (2010). Association of socioeconomic position with health behaviors and mortality. JAMA 303:1159–1166.
Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. (2021). Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 71:209–249.
Suter F, Karavasiloglou N, Hämmig O, Rohrmann S, Pestoni G (2023). Determinants and changes in adherence to the World Cancer Research Fund/American Institute for Cancer Research cancer-prevention recommendations over the past 25 years in Switzerland. Eur J Cancer Prev 32:328–336.
Szadkowska A (2021). Exercise and sport - challenges and benefits for the children and adolescents with type 1 diabetes. Pediatr Endocrinol Diabetes Metab 27:235–236.
Thong MSY, van Noorden CJF, Steindorf K, Arndt V (2020). Cancer-related fatigue: causes and current treatment options. Curr Treat Options Oncol 21:17.
Timmins IR, Jones ME, O’Brien KM, Adami HO, Aune D, Baglietto L, et al. (2024). International pooled analysis of leisure-time physical activity and premenopausal breast cancer in women from 19 cohorts. J Clin Oncol 42:927–939.
Tomida S, Koyama T, Ozaki E, Takashima N, Morita M, Sakaguchi K, et al. (2024). Seven-plus hours of daily sedentary time and the subsequent risk of breast cancer: Japan Multi-Institutional Collaborative Cohort Study. Cancer Sci 115:611–622.
Tsilingiris D, Vallianou NG, Spyrou N, Kounatidis D, Christodoulatos GS, Karampela I, et al. (2023). Obesity and leukemia: biological mechanisms, perspectives, and challenges. Curr Obes Rep 13:1–34.
Tuomilehto J, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, et al.; Finnish Diabetes Prevention Study Group (2001). Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 344:1343–1350.
US Department of Health and Human Services, Office of Disease Prevention and Health Promotion. (2018). Physical Activity Guidelines for Americans, 2nd Edition. https://health.gov/sites/default/files/2019-09/Physical_Activity_Guidelines_2nd_edition.pdf
Vainshelboim B, Muller J, Lima RM, Nead KT, Chester C, Chan K, et al. (2017). Cardiorespiratory fitness and cancer incidence in men. Ann Epidemiol 27:442–447.
Van Blarigan EL, Kenfield SA, Olshen A, Panchal N, Encabo K, Tenggara I, et al. (2024). Effect of a home-based walking intervention on cardiopulmonary fitness and quality of life among men with prostate cancer on active surveillance: the active surveillance exercise randomized controlled trial. Eur Urol Oncol 7:519–526.
Vasilopoulos T, Drozda D, Vincent HK (2024). Physical activity positively impacts disability outcomes during transition from midlife to early older age irrespective of body mass index. Arch Gerontol Geriatr 120:105339.
Vejux J, le Bruchec S, Bernat V, Beauvais G, Beauvais N, Berrut G (2024). Fragilité et qualité de vie, les apports de l’activité physique chez la personne âgée [Fragility and quality of life, the benefits of physical activity for the elderly] [in French]. Geriatr Psychol Neuropsychiatr Vieil 19:127–136.
Verma V, Jafarzadeh N, Boi S, Kundu S, Jiang Z, Fan Y, et al. (2021). MEK inhibition reprograms CD8+ T lymphocytes into memory stem cells with potent antitumor effects. Nat Immunol 22:53–66.
Veronese N, Soysal P, Demurtas J, Solmi M, Bruyère O, Christodoulou N, et al.; Alzheimer Europe (2023). Physical activity and exercise for the prevention and management of mild cognitive impairment and dementia: a collaborative international guideline. Eur Geriatr Med 14:925–952.
Visseren FLJ, Mach F, Smulders YM, Carballo D, Koskinas KC, Bäck M, et al.; ESC Scientific Document Group (2022). 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice: developed by the Task Force for cardiovascular disease prevention in clinical practice with representatives of the European Society of Cardiology and 12 medical societies With the special contribution of the European Association of Preventive Cardiology (EAPC) [in English, Spanish]. Rev Esp Cardiol (Engl Ed) 75:429.
Wagoner CW, Friedenreich CM, Courneya KS, Wang Q, Vallance JK, Matthews CE, et al. (2023). Social-cognitive, demographic, clinical, and health-related correlates of physical activity and sedentary behaviour in newly diagnosed women with breast cancer. Support Care Cancer 31:537.
Wang J, Liu S, Meng X, Zhao X, Wang T, Lei Z, et al. 2024a). Exercise inhibits doxorubicin-induced cardiotoxicity via regulating B cells. Circ Res 134:550–568.
Wang X, Liu M, Stevinson C, Dai YB, Tang YX, Peng D, et al. 2024b). Effect of a single light-intensity walking session on sleep quality of patients with bladder cancer: a randomized cross-over study. Semin Oncol Nurs 40:151571.
Wen CP, Wai JP, Tsai MK, Yang YC, Cheng TY, Lee MC, et al. (2011). Minimum amount of physical activity for reduced mortality and extended life expectancy: a prospective cohort study. Lancet 378:1244–1253.
WHO. (2020). WHO guidelines on physical activity and sedentary behavior. https://www.who.int/publications/i/item/9789240015128 [Accessed 30 April 2024].
Wilcoxon A, Kober KM, Viele C, Topp K, Smoot B, Abrams G, et al. (2020). Association between physical activity levels and chemotherapy-induced peripheral neuropathy severity in cancer survivors. Oncol Nurs Forum 47:703–719.
World Cancer Research Fund/American Institute for Cancer Research. (2018). Diet, nutrition, physical activity and cancer: a global perspective. Continuous Update Project Expert Report. https://www.wcrf.org/wp-content/uploads/2021/02/Summary-of-Third-Expert-Report-2018.pdf. [Accessed 30 April 2024]
Wu J, Wang C, Qi S, Qin Z, Xu H, Hong X (2024). Joint associations of sleep duration and physical activity with cognitive impairment among rural elderly over 65 years old: a cross-sectional study. Psychogeriatrics 24:174–181.
Xiao K, Tang L, Chen Y, Zhou J, Yang Q, Wang R (2024). The effectiveness of E-health interventions promoting physical activity in cancer survivors: a systematic review and meta-analysis of randomized controlled trials. J Cancer Res Clin Oncol 150:72.
Xu J, Wan CS, Ktoris K, Reijnierse EM, Maier AB (2022). Sarcopenia is associated with mortality in adults: a systematic review and meta-analysis. Gerontology 68:361–376.
Yang L, Morielli AR, Heer E, Kirkham AA, Cheung WY, Usmani N, et al. (2021). Effects of exercise on cancer treatment efficacy: a systematic review of preclinical and clinical studies. Cancer Res 81:4889–4895.
Yang HY, Chou YJ, Shun SC (2023). The effect of walking intervention on cognitive function among patients with non-central nervous system cancer: a systematic review. Cancer Nurs 46:375–385.
Zhang Y, Jiang X (2023). The relationship between physical activity and stroke in middle-aged and elderly people after controlling demography variables, health status and lifestyle variables. Medicine (Baltim) 102:e36646.
Zhang XM, Dou QL, Zeng Y, Yang Y, Cheng ASK, Zhang WW (2020). Sarcopenia as a predictor of mortality in women with breast cancer: a meta-analysis and systematic review. BMC Cancer 20:172.
Zhang C, Zhang L, Su Y, Xiang L, Zhang Q, Zhang C, et al. 2024a). Occupational daily walking steps have inverse relationship with papillary thyroid cancer risk and progression: a retrospective analysis. Int J Occup Med Environ Health 37:58–71.
Zhang Y, Zhang K, Huang S, Li W, He P (2024b). A review on associated factors and management measures for sarcopenia in type 2 diabetes mellitus. Medicine (Baltim) 103:e37666.
Zhuang CL, Huang DD, Pang WY, Zhou CJ, Wang SL, Lou N, et al. (2016). Sarcopenia is an independent predictor of severe postoperative complications and long-term survival after radical gastrectomy for gastric cancer: analysis from a large-scale cohort. Medicine (Baltim) 95:e3164.