Mechanistic Insights into the Neurotoxicity of 2,5-Dimethoxyphenethylamines (2C) and Corresponding

2C drugs NBOMe drugs neurotoxicity new psychoactive substances substituted phenethylamines

Journal

Journal of xenobiotics
ISSN: 2039-4713
Titre abrégé: J Xenobiot
Pays: Switzerland
ID NLM: 101701430

Informations de publication

Date de publication:
05 Jun 2024
Historique:
received: 15 04 2024
revised: 17 05 2024
accepted: 30 05 2024
medline: 26 6 2024
pubmed: 26 6 2024
entrez: 26 6 2024
Statut: epublish

Résumé

Substituted phenethylamines including 2C (2,5-dimethoxyphenethylamines) and NBOMe (

Identifiants

pubmed: 38921653
pii: jox14020044
doi: 10.3390/jox14020044
doi:

Types de publication

Journal Article

Langues

eng

Pagination

772-797

Subventions

Organisme : FCT - Fundação para a Ciência e a Tecnologia
ID : scope of the project UIDP/04378/2020 and UIDB/04378/2020 of the Research Unit on Applied Molecular Biosciences-UCIBIO and the project LA/P/0140/2020 of the Associate Laboratory In-stitute for Health and Bioeconomy-i4HB
Organisme : FEDER and FCT
ID : FEDER funds through the Operational Programme Competitiveness Factors-COMPETE and na-tional funds by FCT under research grants UIDB/00081/2020 (CIQUP), LA/P/0056/2020 (IMS) and PT-OPENSCREEN-NORTE-01-0145-FEDER-085468 projects
Organisme : FCT
ID : EGM (SFRH/BD/146527/2019), DM (PD/BD/135122/2017) grants and FCF, DC and CF (CEEC-IND/00823/2021) contracts are supported by FCT and FEDER/COMPETE. DJB is supported by a FCT Junior Researcher position (DL57/2016/CP1355/CT0007)

Auteurs

Eva Gil-Martins (E)

Associate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.
UCIBIO-Applied Molecular Biosciences Unit, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.
CIQUP-IMS/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal.

Fernando Cagide-Fagín (F)

CIQUP-IMS/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal.

Daniel Martins (D)

CIQUP-IMS/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal.

Ana Borer (A)

Associate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.
UCIBIO-Applied Molecular Biosciences Unit, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.

Daniel José Barbosa (DJ)

Associate Laboratory i4HB-Institute for Health and Bioeconomy, University Institute of Health Sciences-CESPU, 4585-116 Gandra, Portugal.
UCIBIO-Applied Molecular Biosciences Unit, Translational Toxicology Research Laboratory, University Institute of Health Sciences (1H-TOXRUN, IUCS-CESPU), 4585-116 Gandra, Portugal.
i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal.

Carlos Fernandes (C)

CIQUP-IMS/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal.

Daniel Chavarria (D)

CIQUP-IMS/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal.

Fernando Remião (F)

Associate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.
UCIBIO-Applied Molecular Biosciences Unit, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.

Fernanda Borges (F)

CIQUP-IMS/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal.

Renata Silva (R)

Associate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.
UCIBIO-Applied Molecular Biosciences Unit, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.

Classifications MeSH