Potassium dichromate sensitivity presenting as tefillin dermatitis: A retrospective cohort study.

allergic contact dermatitis contact allergy patch test potassium dichromate tefillin tefillin dermatitis

Journal

Contact dermatitis
ISSN: 1600-0536
Titre abrégé: Contact Dermatitis
Pays: England
ID NLM: 7604950

Informations de publication

Date de publication:
24 Jun 2024
Historique:
revised: 11 06 2024
received: 04 05 2024
accepted: 12 06 2024
medline: 26 6 2024
pubmed: 26 6 2024
entrez: 26 6 2024
Statut: aheadofprint

Résumé

Tefillin are a religious article worn by Jewish men during daily prayer. Tefillin dermatitis secondary to potassium dichromate sensitivity is recognised, but data remain sparse. To investigate the prevalence and clinical characteristics of tefillin dermatitis. Patients who underwent patch testing with the European baseline series in a tertiary dermatology clinic in 2009-2023 and were diagnosed with tefillin dermatitis were identified by file review and their clinical data recorded. Of 1679 consecutive male patients tested, 25 (1.49%) were diagnosed with tefillin dermatitis, accounting for 15.34% of all potassium-dichromate-positive patients (163/1679). Mean pre-symptomatic duration of tefillin use was 38 ± 16.9 years, and mean follow-up time, 3.1 ± 2.9 years. Patients presented with an eczematous rash on body areas in direct contact with the leather box or straps of the tefillin. An id reaction was noted in 32%, and sensitivity to other leather accessories, in 44%. Fourteen patients (56%) switched to chromate-free tefillin: symptoms resolved completely in 11 (79%) and partially in 2. Retrospective cohort design. This is the largest study to date of tefillin dermatitis caused by sensitivity to potassium dichromate used in leather production. Prognosis after switching to chromate-free tefillin was good-to-excellent. Tefillin dermatitis may be more prevalent than previously thought.

Sections du résumé

BACKGROUND BACKGROUND
Tefillin are a religious article worn by Jewish men during daily prayer. Tefillin dermatitis secondary to potassium dichromate sensitivity is recognised, but data remain sparse.
OBJECTIVE OBJECTIVE
To investigate the prevalence and clinical characteristics of tefillin dermatitis.
METHODS METHODS
Patients who underwent patch testing with the European baseline series in a tertiary dermatology clinic in 2009-2023 and were diagnosed with tefillin dermatitis were identified by file review and their clinical data recorded.
RESULTS RESULTS
Of 1679 consecutive male patients tested, 25 (1.49%) were diagnosed with tefillin dermatitis, accounting for 15.34% of all potassium-dichromate-positive patients (163/1679). Mean pre-symptomatic duration of tefillin use was 38 ± 16.9 years, and mean follow-up time, 3.1 ± 2.9 years. Patients presented with an eczematous rash on body areas in direct contact with the leather box or straps of the tefillin. An id reaction was noted in 32%, and sensitivity to other leather accessories, in 44%. Fourteen patients (56%) switched to chromate-free tefillin: symptoms resolved completely in 11 (79%) and partially in 2.
LIMITATIONS CONCLUSIONS
Retrospective cohort design.
CONCLUSION CONCLUSIONS
This is the largest study to date of tefillin dermatitis caused by sensitivity to potassium dichromate used in leather production. Prognosis after switching to chromate-free tefillin was good-to-excellent. Tefillin dermatitis may be more prevalent than previously thought.

Identifiants

pubmed: 38923529
doi: 10.1111/cod.14627
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Références

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Auteurs

Daniel Hilewitz (D)

Department of Dermatology, Rabin Medical Center - Beilinson Hospital, Petach Tikva, Israel.
Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Akiva Trattner (A)

Department of Dermatology, Rabin Medical Center - Beilinson Hospital, Petach Tikva, Israel.
Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Yehonatan Noyman (Y)

Department of Dermatology, Rabin Medical Center - Beilinson Hospital, Petach Tikva, Israel.
Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Daniel Mimouni (D)

Department of Dermatology, Rabin Medical Center - Beilinson Hospital, Petach Tikva, Israel.
Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Igor Snast (I)

Department of Dermatology, Rabin Medical Center - Beilinson Hospital, Petach Tikva, Israel.
Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Classifications MeSH