Subpectineal obturator nerve block reduces opioid consumption after hip arthroscopy: a triple-blind, randomized, placebo-controlled trial.

Lower Extremity Nerve Block Pain Management Pain, Postoperative Ultrasonography

Journal

Regional anesthesia and pain medicine
ISSN: 1532-8651
Titre abrégé: Reg Anesth Pain Med
Pays: England
ID NLM: 9804508

Informations de publication

Date de publication:
25 Jun 2024
Historique:
received: 02 05 2024
accepted: 12 06 2024
medline: 27 6 2024
pubmed: 27 6 2024
entrez: 26 6 2024
Statut: aheadofprint

Résumé

Hip arthroscopy causes severe pain during the first few hours in the postoperative care unit. This is probably due to the intraoperative stretching of the hip joint capsule. Pain relief requires high doses of opioids which may prolong recovery and may cause opioid-related adverse events.The majority of hip joint capsule nociceptors are located anteriorly. The obturator nerve innervates the anteromedial part of the hip joint capsule. We hypothesized that a subpectineal obturator nerve block using 15 ml bupivacaine 5 mg/mL with added epinephrine 5 μg/mL would reduce the opioid consumption after hip arthroscopy. 40 ambulatory hip arthroscopy patients were enrolled in this randomized, triple-blind controlled trial. All patients were allocated to a preoperative active or placebo subpectineal obturator nerve block. The primary outcome was opioid consumption for the first 3 hours in the postanesthesia care unit. Secondary outcomes were pain, nausea, and hip adductor strength. 34 patients were analyzed for the primary outcome. The mean intravenous morphine equivalent consumption in the subpectineal obturator nerve block group was 11.9 mg vs 19.7 mg in the placebo group (p<0.001). The hip adductor strength was significantly reduced in the active group. No other intergroup differences were observed regarding the secondary outcomes. We found a significant reduction in the opioid consumption for patients receiving an active subpectineal obturator nerve block. The postoperative intravenous morphine equivalent reduction the first painful 3 hours was reduced by 40% for patients receiving a subpectineal obturator nerve block in this randomized, triple-blind trial. EudraCT database 2021-006575-42.

Sections du résumé

BACKGROUND BACKGROUND
Hip arthroscopy causes severe pain during the first few hours in the postoperative care unit. This is probably due to the intraoperative stretching of the hip joint capsule. Pain relief requires high doses of opioids which may prolong recovery and may cause opioid-related adverse events.The majority of hip joint capsule nociceptors are located anteriorly. The obturator nerve innervates the anteromedial part of the hip joint capsule. We hypothesized that a subpectineal obturator nerve block using 15 ml bupivacaine 5 mg/mL with added epinephrine 5 μg/mL would reduce the opioid consumption after hip arthroscopy.
METHODS METHODS
40 ambulatory hip arthroscopy patients were enrolled in this randomized, triple-blind controlled trial. All patients were allocated to a preoperative active or placebo subpectineal obturator nerve block. The primary outcome was opioid consumption for the first 3 hours in the postanesthesia care unit. Secondary outcomes were pain, nausea, and hip adductor strength.
RESULTS RESULTS
34 patients were analyzed for the primary outcome. The mean intravenous morphine equivalent consumption in the subpectineal obturator nerve block group was 11.9 mg vs 19.7 mg in the placebo group (p<0.001). The hip adductor strength was significantly reduced in the active group. No other intergroup differences were observed regarding the secondary outcomes.
CONCLUSION CONCLUSIONS
We found a significant reduction in the opioid consumption for patients receiving an active subpectineal obturator nerve block. The postoperative intravenous morphine equivalent reduction the first painful 3 hours was reduced by 40% for patients receiving a subpectineal obturator nerve block in this randomized, triple-blind trial.
TRIAL REGISTRATION NUMBER BACKGROUND
EudraCT database 2021-006575-42.

Identifiants

pubmed: 38925710
pii: rapm-2024-105638
doi: 10.1136/rapm-2024-105638
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© American Society of Regional Anesthesia & Pain Medicine 2024. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Christian Jessen (C)

Department of Anesthesiology and Intensive Care, PeriSCOP, Horsens Regional Hospital, Horsens, Denmark jessen_chr@hotmail.com.
Department of Clinical Medicine, Aarhus University Faculty of Health, Aarhus, Denmark.

Ulrick Skipper Espelund (US)

Department of Anesthesiology and Intensive Care, PeriSCOP, Horsens Regional Hospital, Horsens, Denmark.
Department of Clinical Medicine, Aarhus University Faculty of Health, Aarhus, Denmark.

Lone Dragnes Brix (LD)

Department of Anesthesiology and Intensive Care, PeriSCOP, Horsens Regional Hospital, Horsens, Denmark.
Department of Clinical Medicine, Aarhus University Faculty of Health, Aarhus, Denmark.

Thomas Dahl Nielsen (TD)

Department of Clinical Medicine, Aarhus University Faculty of Health, Aarhus, Denmark.

Bent Lund (B)

Department of Clinical Medicine, Aarhus University Faculty of Health, Aarhus, Denmark.
Department of Orthopedic Surgery, H-Hip, Horsens Regional Hospital, Horsens, Denmark.

Thomas Fichtner Bendtsen (TF)

Department of Clinical Medicine, Aarhus University Faculty of Health, Aarhus, Denmark.
Department of Anesthesiology, Aarhus University Hospital, Aarhus, Denmark.

Classifications MeSH