Update on the Management of Low-stage Seminoma.

Chemotherapy Germ cell tumor MicroRNA-371a-3p Radiotherapy Retroperitoneal lymph node dissection Seminoma Surveillance Testicular cancer

Journal

The Urologic clinics of North America
ISSN: 1558-318X
Titre abrégé: Urol Clin North Am
Pays: United States
ID NLM: 0423221

Informations de publication

Date de publication:
Aug 2024
Historique:
medline: 27 6 2024
pubmed: 27 6 2024
entrez: 26 6 2024
Statut: ppublish

Résumé

The contemporary paradigm of testicular cancer management is achieving high and durable cure rates while minimizing the burden of treatment given the potential long-term toxicities associated with radiation therapy and systemic therapies. The management of low-stage seminoma has seen significant changes in recent years. Nuances of surveillance strategies for stage I seminoma exist and continue to evolve. Emerging data show retroperitoneal lymph node dissection is a viable treatment option for selected patients with clinical stage IIA and IIB seminoma.

Identifiants

pubmed: 38925740
pii: S0094-0143(24)00031-4
doi: 10.1016/j.ucl.2024.03.006
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

377-385

Informations de copyright

Copyright © 2024 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure The authors declare no commercial or financial conflicts of interest, or any funding sources related to this study. S. Daneshmand has Stock and Other Ownership Interests with Taris, Honoraria: Photocure, QED Therapeutics, Olympus, Ferring, Pacific Edge, Urogene, Johnson & Johnson, Janssen, Bristol Myers Squibb, and Allergan. S. Daneshmand served in Consulting or Advisory Role for Photocure, Taris, Ferring, and QED Therapeutics. Travel, Accommodations, and Expenses: Photocure.

Auteurs

Leilei Xia (L)

Department of Urology, USC/Norris Comprehensive Cancer Center, University of Southern California, 1441 Eastlake Avenue, Suite 7416, Los Angeles, CA 90089, USA. Electronic address: leilei.xia@med.usc.edu.

Siamak Daneshmand (S)

Department of Urology, USC/Norris Comprehensive Cancer Center, University of Southern California, 1441 Eastlake Avenue, Suite 7416, Los Angeles, CA 90089, USA.

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Classifications MeSH