Contemporary Role of Radiation Therapy in Testicular Cancer.
-node radiation therapy
Dose de-escalation
Involved
Modified dog-leg
Para-aortic strip
Proton radiation
Radiation therapy
Testicular seminoma
Journal
The Urologic clinics of North America
ISSN: 1558-318X
Titre abrégé: Urol Clin North Am
Pays: United States
ID NLM: 0423221
Informations de publication
Date de publication:
Aug 2024
Aug 2024
Historique:
medline:
27
6
2024
pubmed:
27
6
2024
entrez:
26
6
2024
Statut:
ppublish
Résumé
Testicular cancer is a rare but curable male malignancy. Seminoma represents the majority of germ cell tumors and is considered radiation sensitive. Radiation treatment plays a role in adjuvant therapy after orchiectomy of stage I, IIA, and IIB seminomas. Radiation dose de-escalation has been effective in preventing tumor recurrences while also limiting acute and long-term toxicities. However, long-term risks, including the prevailing concern of secondary malignancy risk, between adjuvant radiation and chemotherapy play a role in recommendations. Ongoing work continues to be performed to reduce radiation field and dose in combination with chemotherapy while still maintaining excellent outcomes.
Identifiants
pubmed: 38925742
pii: S0094-0143(24)00033-8
doi: 10.1016/j.ucl.2024.03.008
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
395-405Informations de copyright
Copyright © 2024 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Disclosure The authors have nothing to disclose.