Structural Insights into the Rrp4 Subunit from the Crystal Structure of the

Thermoplasma / metabolism Exosomes / metabolism Crystallography, X-Ray Archaeal Proteins / chemistry Models, Molecular Protein Subunits / chemistry Exosome Multienzyme Ribonuclease Complex / metabolism RNA Stability
PNPase RNA processing RNase exosome quality control

Journal

Biomolecules
ISSN: 2218-273X
Titre abrégé: Biomolecules
Pays: Switzerland
ID NLM: 101596414

Informations de publication

Date de publication:
24 May 2024
Historique:
received: 27 04 2024
revised: 16 05 2024
accepted: 23 05 2024
medline: 27 6 2024
pubmed: 27 6 2024
entrez: 27 6 2024
Statut: epublish

Résumé

The exosome multiprotein complex plays a critical role in RNA processing and degradation. This system governs the regulation of mRNA quality, degradation in the cytoplasm, the processing of short noncoding RNA, and the breakdown of RNA fragments. We determined two crystal structures of exosome components from

Identifiants

DOI: 10.3390/biom14060621 PMID: 38927025
pubmed: 38927025
pii: biom14060621
doi: 10.3390/biom14060621
pii:
doi:

Substances chimiques

Archaeal Proteins 0
Protein Subunits 0
Exosome Multienzyme Ribonuclease Complex EC 3.1.-

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : National Research Foundation of Korea
ID : 2020R1A2C2005670
Organisme : National Research Foundation of Korea
ID : 2022R1I1A1A01068223

Auteurs

Seonha Park (S)

Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Republic of Korea.
Institute of Bioresources, Korea University, Seoul 02841, Republic of Korea.
ORCID: 0009-0002-1786-0448

Hyun Sook Kim (HS)

Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Republic of Korea.

Kyuhyeon Bang (K)

Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Republic of Korea.

Ahreum Han (A)

Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Republic of Korea.

Byeongmin Shin (B)

Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Republic of Korea.

Minjeong Seo (M)

Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Republic of Korea.

Sulhee Kim (S)

Korea BioDefense Research Institute, Korea University, Seoul 02841, Republic of Korea.
ORCID: 0000-0002-8303-1376

Kwang Yeon Hwang (KY)

Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Republic of Korea.
ORCID: 0000-0002-2076-5030

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Classifications MeSH

questionsmedicales.fr › Archéobactéries › Euryarchaeota › Thermoplasmales › Thermoplasma › Structural Insights into the Rrp4 Subunit from...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Vésicules cytoplasmiques › Vésicules de transport › Exosomes › Structural Insights into the Rrp4 Subunit from...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Cristallographie aux rayons X › Structural Insights into the Rrp4 Subunit from...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines d'archée › Structural Insights into the Rrp4 Subunit from...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles moléculaires › Structural Insights into the Rrp4 Subunit from...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Sous-unités de protéines › Structural Insights into the Rrp4 Subunit from...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Complexes multienzymatiques › Exosome multienzyme ribonuclease complex › Structural Insights into the Rrp4 Subunit from...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Stabilité de l'ARN › Structural Insights into the Rrp4 Subunit from...