Multi-Scale Digital Pathology Patch-Level Prostate Cancer Grading Using Deep Learning: Use Case Evaluation of DiagSet Dataset.

health care machine learning prostate cancer classification

Journal

Bioengineering (Basel, Switzerland)
ISSN: 2306-5354
Titre abrégé: Bioengineering (Basel)
Pays: Switzerland
ID NLM: 101676056

Informations de publication

Date de publication:
18 Jun 2024
Historique:
received: 06 05 2024
revised: 03 06 2024
accepted: 12 06 2024
medline: 27 6 2024
pubmed: 27 6 2024
entrez: 27 6 2024
Statut: epublish

Résumé

Prostate cancer remains a prevalent health concern, emphasizing the critical need for early diagnosis and precise treatment strategies to mitigate mortality rates. The accurate prediction of cancer grade is paramount for timely interventions. This paper introduces an approach to prostate cancer grading, framing it as a classification problem. Leveraging ResNet models on multi-scale patch-level digital pathology and the Diagset dataset, the proposed method demonstrates notable success, achieving an accuracy of 0.999 in identifying clinically significant prostate cancer. The study contributes to the evolving landscape of cancer diagnostics, offering a promising avenue for improved grading accuracy and, consequently, more effective treatment planning. By integrating innovative deep learning techniques with comprehensive datasets, our approach represents a step forward in the pursuit of personalized and targeted cancer care.

Identifiants

pubmed: 38927860
pii: bioengineering11060624
doi: 10.3390/bioengineering11060624
pii:
doi:

Types de publication

Journal Article

Langues

eng

Auteurs

Tanaya Kondejkar (T)

College of Engineering, Northeastern University, Boston, MA 02115, USA.

Salah Mohammed Awad Al-Heejawi (SMA)

College of Engineering, Northeastern University, Boston, MA 02115, USA.

Anne Breggia (A)

MaineHealth Institute for Research, Scarborough, ME 04074, USA.

Bilal Ahmad (B)

Maine Medical Center, Portland, ME 04102, USA.

Robert Christman (R)

Maine Medical Center, Portland, ME 04102, USA.

Stephen T Ryan (ST)

Maine Medical Center, Portland, ME 04102, USA.

Saeed Amal (S)

The Roux Institute, Department of Bioengineering, College of Engineering, Northeastern University, Boston, MA 02115, USA.

Classifications MeSH