Diagnostic Yield of Endoscopic Ultrasound-Guided Liver Biopsy in Comparison to Percutaneous Liver Biopsy: A Meta-Analysis of Randomized Controlled Trials and Trial Sequential Analysis.

EUS FNA FNB adequacy cirrhosis tissue

Journal

Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402

Informations de publication

Date de publication:
12 Jun 2024
Historique:
received: 30 05 2024
revised: 08 06 2024
accepted: 11 06 2024
medline: 27 6 2024
pubmed: 27 6 2024
entrez: 27 6 2024
Statut: epublish

Résumé

The efficacy of endoscopic ultrasound-guided liver biopsy (EUS-LB) compared to percutaneous liver biopsy (PC-LB) remains uncertain. Our data consist of randomized controlled trials (RCTs) comparing EUS-LB to PC-LB, found through a literature search via PubMed/Medline and Embase. The primary outcome was sample adequacy, whereas secondary outcomes were longest and total lengths of tissue specimens, diagnostic accuracy, and number of complete portal tracts (CPTs). Sample adequacy did not significantly differ between EUS-LB and PC-LB (risk ratio [RR] 1.18; 95% confidence interval [CI] 0.58-2.38; EUS-LB and PC-LB are comparable in terms of diagnostic performance although PC-LB provides longer non-fragmented specimens.

Sections du résumé

BACKGROUND BACKGROUND
The efficacy of endoscopic ultrasound-guided liver biopsy (EUS-LB) compared to percutaneous liver biopsy (PC-LB) remains uncertain.
METHODS METHODS
Our data consist of randomized controlled trials (RCTs) comparing EUS-LB to PC-LB, found through a literature search via PubMed/Medline and Embase. The primary outcome was sample adequacy, whereas secondary outcomes were longest and total lengths of tissue specimens, diagnostic accuracy, and number of complete portal tracts (CPTs).
RESULTS RESULTS
Sample adequacy did not significantly differ between EUS-LB and PC-LB (risk ratio [RR] 1.18; 95% confidence interval [CI] 0.58-2.38;
CONCLUSION CONCLUSIONS
EUS-LB and PC-LB are comparable in terms of diagnostic performance although PC-LB provides longer non-fragmented specimens.

Identifiants

pubmed: 38928653
pii: diagnostics14121238
doi: 10.3390/diagnostics14121238
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Auteurs

Megha Bhandari (M)

Hepatology Department, Cambridge University Hospital, Cambridge CB4 1GN, UK.

Jayanta Samanta (J)

Gastroenterology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.

Marco Spadaccini (M)

Endoscopy Unit, Department of Biomedical Sciences, Humanitas University, Humanitas Clinical and Research Center IRCCS, Rozzano, 20089 Milan, Italy.

Alessandro Fugazza (A)

Endoscopy Unit, Department of Biomedical Sciences, Humanitas University, Humanitas Clinical and Research Center IRCCS, Rozzano, 20089 Milan, Italy.

Stefano Francesco Crinò (SF)

Diagnostic and Interventional Endoscopy of Pancreas, Pancreas Institute, University of Verona, 37134 Verona, Italy.

Paraskevas Gkolfakis (P)

Department of Gastroenterology, General Hospital of Nea Ionia "Konstantopoulio-Patision", 142 33 Athens, Greece.

Konstantinos Triantafyllou (K)

Hepatogastroenterology Unit, Second Department of Internal Medicine-Propaedeutic, Medical School, National and Kapodistrian University of Athens, "Attikon" University General Hospital, 124 62 Athens, Greece.

Jahnvi Dhar (J)

Gastroenterology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.

Marcello Maida (M)

Faculty of Medicine, "Kore" University of Enna, 94100 Enna, Italy.

Nicola Pugliese (N)

Endoscopy Unit, Department of Biomedical Sciences, Humanitas University, Humanitas Clinical and Research Center IRCCS, Rozzano, 20089 Milan, Italy.

Cesare Hassan (C)

Endoscopy Unit, Department of Biomedical Sciences, Humanitas University, Humanitas Clinical and Research Center IRCCS, Rozzano, 20089 Milan, Italy.

Alessandro Repici (A)

Endoscopy Unit, Department of Biomedical Sciences, Humanitas University, Humanitas Clinical and Research Center IRCCS, Rozzano, 20089 Milan, Italy.

Alessio Aghemo (A)

Endoscopy Unit, Department of Biomedical Sciences, Humanitas University, Humanitas Clinical and Research Center IRCCS, Rozzano, 20089 Milan, Italy.

Gaetano Serviddio (G)

Gastroenterology Unit, Department of Medical and Surgical Sciences, University of Foggia, Via L Pinto 1, 71122 Foggia, Italy.

Antonio Facciorusso (A)

Gastroenterology Unit, Department of Medical and Surgical Sciences, University of Foggia, Via L Pinto 1, 71122 Foggia, Italy.

Classifications MeSH