Consequences of Maternal Vitamin D Deficiency on Newborn Health.

newborn outcome vitamin D deficiency vitamin D in pregnancy

Journal

Life (Basel, Switzerland)
ISSN: 2075-1729
Titre abrégé: Life (Basel)
Pays: Switzerland
ID NLM: 101580444

Informations de publication

Date de publication:
31 May 2024
Historique:
received: 25 04 2024
revised: 27 05 2024
accepted: 29 05 2024
medline: 27 6 2024
pubmed: 27 6 2024
entrez: 27 6 2024
Statut: epublish

Résumé

Maternal-fetal gestational pathology is one of the biggest challenges in the field of health at this moment. The current study is designed to determine the effects of vitamin D on pregnancy, starting with the idea that impairment of vitamin D status is thought to be correlated with impairment of the newborn's health. In this retrospective study, we tried to establish the link between vitamin D deficiency and maternal characteristics and also how it impacted the clinical status of the newborn. We analyzed a group of 260 patients: 130 pregnant women and 130 newborns, in whom vitamin D status was detected using the serum levels of 25-hydroxyvitamin D (25-(OH)D). The results showed that vitamin D deficiency has a high incidence among pregnant women, as was presented in many important international studies. Our study also showed a positive, direct correlation between the mother's and newborn's vitamin D status. Taking into consideration that vitamin D deficiency has been correlated with many complications, both in maternal and newborn health, a serum level determination of 25-(OH)D is necessary in the first trimester of pregnancy, and after that, adequate supplementation is necessary in order to prevent any negative effects.

Sections du résumé

BACKGROUND AND OBJECTIVES OBJECTIVE
Maternal-fetal gestational pathology is one of the biggest challenges in the field of health at this moment. The current study is designed to determine the effects of vitamin D on pregnancy, starting with the idea that impairment of vitamin D status is thought to be correlated with impairment of the newborn's health.
MATERIALS AND METHODS METHODS
In this retrospective study, we tried to establish the link between vitamin D deficiency and maternal characteristics and also how it impacted the clinical status of the newborn. We analyzed a group of 260 patients: 130 pregnant women and 130 newborns, in whom vitamin D status was detected using the serum levels of 25-hydroxyvitamin D (25-(OH)D).
RESULTS RESULTS
The results showed that vitamin D deficiency has a high incidence among pregnant women, as was presented in many important international studies. Our study also showed a positive, direct correlation between the mother's and newborn's vitamin D status.
CONCLUSIONS CONCLUSIONS
Taking into consideration that vitamin D deficiency has been correlated with many complications, both in maternal and newborn health, a serum level determination of 25-(OH)D is necessary in the first trimester of pregnancy, and after that, adequate supplementation is necessary in order to prevent any negative effects.

Identifiants

pubmed: 38929697
pii: life14060714
doi: 10.3390/life14060714
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Carol Davila University of Medicine and Pharmacy
ID : Publish not Perish

Auteurs

Ramona Elena Dragomir (RE)

Doctoral School, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Daniela Oana Toader (DO)

Department of Obstetrics and Gynecology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Daniela Elena Gheoca Mutu (DE)

Discipline of Anatomy, Department 2-Morphological Sciences, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Iulian Alexandru Dogaru (IA)

Doctoral School, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Discipline of Anatomy, Department 2-Morphological Sciences, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Laura Răducu (L)

Discipline of Plastic Surgery, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Laurențiu Cezar Tomescu (LC)

Department of Obstetrics and Gynecology, "Ovidius" University of Constanța, 900527 Constanța, Romania.

Lavinia Cristina Moleriu (LC)

Discipline of Medical Informatics and Biostatistics, Department 3-Functional Sciences, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timisoara, Romania.

Anca Bordianu (A)

Discipline of Plastic Surgery, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Ion Petre (I)

Discipline of Medical Informatics and Biostatistics, Department 3-Functional Sciences, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timisoara, Romania.

Ruxandra Stănculescu (R)

Doctoral School, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Classifications MeSH