Allosteric Modulators of Serotonin Receptors: A Medicinal Chemistry Survey.

GPCR allosteric modulators cannabinoids natural compounds serotonin

Journal

Pharmaceuticals (Basel, Switzerland)
ISSN: 1424-8247
Titre abrégé: Pharmaceuticals (Basel)
Pays: Switzerland
ID NLM: 101238453

Informations de publication

Date de publication:
28 May 2024
Historique:
received: 30 04 2024
revised: 15 05 2024
accepted: 23 05 2024
medline: 27 6 2024
pubmed: 27 6 2024
entrez: 27 6 2024
Statut: epublish

Résumé

Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter regulating numerous physiological functions, and its dysregulation is a crucial component of the pathological processes of schizophrenia, depression, migraines, and obesity. 5-HT interacts with 14 different receptors, of which 5-HT

Identifiants

pubmed: 38931362
pii: ph17060695
doi: 10.3390/ph17060695
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Subventions

Organisme : Italian Ministry of University and Research (MUR)
ID : Project MNESYS (PE0000006) - A Multiscale integrated approach to the study of the nervous sys-tem in health and disease

Auteurs

Leonardo Brunetti (L)

Department of Pharmacy-Drug Sciences, University of Bari Aldo Moro, 70125 Bari, Italy.

Fabio Francavilla (F)

Department of Pharmacy-Drug Sciences, University of Bari Aldo Moro, 70125 Bari, Italy.

Marcello Leopoldo (M)

Department of Pharmacy-Drug Sciences, University of Bari Aldo Moro, 70125 Bari, Italy.

Enza Lacivita (E)

Department of Pharmacy-Drug Sciences, University of Bari Aldo Moro, 70125 Bari, Italy.

Classifications MeSH