Impact of Weight Gain on Cardiovascular Outcomes in Patients With Atrial Fibrillation.

atrial fibrillation obesity risk factors

Journal

Journal of the American Heart Association
ISSN: 2047-9980
Titre abrégé: J Am Heart Assoc
Pays: England
ID NLM: 101580524

Informations de publication

Date de publication:
27 Jun 2024
Historique:
medline: 27 6 2024
pubmed: 27 6 2024
entrez: 27 6 2024
Statut: aheadofprint

Résumé

The long-term impact of weight gain (WG) on cardiovascular outcomes among patients with atrial fibrillation (AF) is unclear. We studied 62 871 (mean age, 72±12, 43% women) adult patients with AF evaluated at the University of Pittsburgh Medical Center between January 1, 2010, and May 13, 2021. Serial body mass index, risk factors, comorbidities, and subsequent death and hospitalization were ascertained and stratified according to percentage WG (≥0% to <5%, ≥5% to <10%, and ≥10%). Over 4.9±3.19 years of follow-up, 27 114 (43%) patients gained weight (61%, ≥0% to <5%; 23%, ≥5% to <10%; 16%, ≥10%). Patients with progressive WG were incrementally younger ( Among patients with AF, WG is incrementally associated with increased hospitalization for cardiovascular causes, particularly heart failure, stroke, myocardial infarction, and AF.

Sections du résumé

BACKGROUND BACKGROUND
The long-term impact of weight gain (WG) on cardiovascular outcomes among patients with atrial fibrillation (AF) is unclear.
METHODS AND RESULTS RESULTS
We studied 62 871 (mean age, 72±12, 43% women) adult patients with AF evaluated at the University of Pittsburgh Medical Center between January 1, 2010, and May 13, 2021. Serial body mass index, risk factors, comorbidities, and subsequent death and hospitalization were ascertained and stratified according to percentage WG (≥0% to <5%, ≥5% to <10%, and ≥10%). Over 4.9±3.19 years of follow-up, 27 114 (43%) patients gained weight (61%, ≥0% to <5%; 23%, ≥5% to <10%; 16%, ≥10%). Patients with progressive WG were incrementally younger (
CONCLUSIONS CONCLUSIONS
Among patients with AF, WG is incrementally associated with increased hospitalization for cardiovascular causes, particularly heart failure, stroke, myocardial infarction, and AF.

Identifiants

pubmed: 38934853
doi: 10.1161/JAHA.123.032550
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e032550

Auteurs

Aditya Bhonsale (A)

Section of Cardiac Electrophysiology, Division of Cardiology University of Pittsburgh Medical Center Pittsburgh PA USA.

Jianhui Zhu (J)

Department of Cardiology University of Pittsburgh Medical Center Pittsburgh PA USA.

Floyd Thoma (F)

Department of Cardiology University of Pittsburgh Medical Center Pittsburgh PA USA.

Krishna Kancharla (K)

Section of Cardiac Electrophysiology, Division of Cardiology University of Pittsburgh Medical Center Pittsburgh PA USA.

Andrew Voigt (A)

Section of Cardiac Electrophysiology, Division of Cardiology University of Pittsburgh Medical Center Pittsburgh PA USA.

Nathan A Estes (NA)

Section of Cardiac Electrophysiology, Division of Cardiology University of Pittsburgh Medical Center Pittsburgh PA USA.

Alaa A Shalaby (AA)

Section of Cardiac Electrophysiology, Division of Cardiology University of Pittsburgh Medical Center Pittsburgh PA USA.

Samir Saba (S)

Section of Cardiac Electrophysiology, Division of Cardiology University of Pittsburgh Medical Center Pittsburgh PA USA.

Suresh Mulukutla (S)

Department of Cardiology University of Pittsburgh Medical Center Pittsburgh PA USA.

Sandeep Jain (S)

Section of Cardiac Electrophysiology, Division of Cardiology University of Pittsburgh Medical Center Pittsburgh PA USA.

Classifications MeSH