Long-term outcomes of surgical repair for corrected transposition of the great arteries.

BACKGROUND

This study investigated the long-term outcomes of physiological and anatomical repair for corrected transposition of the great arteries and double outlet right ventricle with discordant atrioventricular connection.

METHODS

This single-center retrospective study included 146 patients who underwent biventricular repair of corrected transposition of the great arteries or double outlet right ventricle with discordant atrioventricular connections from 1972 to 2023. Survival rate, freedom from reoperation, NYHA classification and incidence of systemic ventricular dysfunction in the long-term were compared between physiological repair group (PR group) and anatomical repair group (AR group).

RESULTS

PR group consisted of 55 patients with median age at repair of 10.3 years. Thirty-one patients underwent conventional Rastelli procedure and 24 patients underwent atrial and/or ventricular septal defect closure. AR group consisted of 91 patients with median age at repair of 5.8 years. Seventy-two patients underwent atrial switch plus Rastelli procedure and 19 patients underwent atrial plus arterial switch operation. The 30-year survival was 63.5% in PR group and 72.3% in AR group (p=0.448). The 30-year freedom from reoperation was 71.9% in PR group and 62.2% in AR group (p=0.220). There was a significant difference in incidence of systemic ventricular dysfunction between the groups (87.5% in PR group and 35.3% in AR group: p<0.001) and long-term survivors' NYHA classification (mean NYHA class of 1.9 in PR group and 1.5 in AR group: p=0.009).

CONCLUSIONS

The systemic ventricular function and general status in the long-term were significantly better in anatomical repair patients, suggesting the potential advantage of anatomical repair.

Informations de copyright

Copyright © 2024. Published by Elsevier Inc.