Experimental observation of cavity-free ice-free isochoric vitrification via combined pressure measurements and photon counting x-ray computed tomography.

Journal

Cryobiology
ISSN: 1090-2392
Titre abrégé: Cryobiology
Pays: Netherlands
ID NLM: 0006252

Informations de publication

Date de publication:
25 Jun 2024
Historique:
received: 29 03 2024
revised: 04 06 2024
accepted: 24 06 2024
medline: 28 6 2024
pubmed: 28 6 2024
entrez: 27 6 2024
Statut: aheadofprint

Résumé

Isochoric (constant-volume or volumetrically confined) vitrification has shown potential as an alternative cryopreservation-by-vitrification technique, but the complex processes at play within the chamber are yet poorly characterized, and recent investigations have prompted significant debate around whether a truly isochoric vitrification process (in which the liquid remains completely confined by solid boundaries) is indeed feasible. Based on a recent thermomechanical simulation of a high-concentration Me

Identifiants

DOI: 10.1016/j.cryobiol.2024.104935 PMID: 38936595
pubmed: 38936595
pii: S0011-2240(24)00090-7
doi: 10.1016/j.cryobiol.2024.104935
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

104935

Informations de copyright

Copyright © 2024. Published by Elsevier Inc.

Déclaration de conflit d'intérêts

Declaration of Competing Interest B.R. has filed a 2017 patent application related to isochoric vitrification, which is under review as of the date of submission of this work. M.J.P.-P. and B.R. have financial stakes in a commercial entity that holds the license to the said patent application. The other authors declare no competing interests.

Auteurs

Alaa M Ali (AM)

Department of Mechanical Engineering, University of California, Berkeley, Berkeley, CA, USA.

Brooke Chang (B)

Department of Mechanical Engineering, University of California, Berkeley, Berkeley, CA, USA.

Anthony N Consiglio (AN)

Department of Mechanical Engineering, University of California, Berkeley, Berkeley, CA, USA.

Gala Sanchez Van Moer (GS)

Department of Mechanical Engineering, University of California, Berkeley, Berkeley, CA, USA.

Matthew J Powell-Palm (MJ)

Department of Mechanical Engineering, University of California, Berkeley, Berkeley, CA, USA; J. Mike Walker '66 Department of Mechanical Engineering, Texas A&M University, College Station, Texas, USA; Department of Materials Science and Engineering, Texas A&M University, College Station, Texas, USA.

Boris Rubinsky (B)

Department of Mechanical Engineering, University of California, Berkeley, Berkeley, CA, USA.

Simo A Mäkiharju (SA)

Department of Mechanical Engineering, University of California, Berkeley, Berkeley, CA, USA. Electronic address: makiharju@berkeley.edu.

Classifications MeSH