Women With Acute Aortic Dissection Have Higher Prehospital Mortality Than Men.
acute aortic dissection
incidence
prehospital mortality
sex difference
Journal
JACC. Advances
ISSN: 2772-963X
Titre abrégé: JACC Adv
Pays: United States
ID NLM: 9918419284106676
Informations de publication
Date de publication:
Oct 2023
Oct 2023
Historique:
received:
03
03
2023
revised:
29
06
2023
accepted:
26
07
2023
medline:
28
6
2024
pubmed:
28
6
2024
entrez:
28
6
2024
Statut:
epublish
Résumé
Acute aortic dissection (AAD) often leads to out-of-hospital cardiac arrest (OHCA) and death before hospital arrival. The purpose of this study was to investigate differences in AAD incidence by sex. A population-based study in a city with 121,180 residents was conducted using postmortem computed tomography data to identify patients with AAD who died before hospital arrival in 2008-2020. The incidence rate ratio and odds ratio were estimated using Poisson regression and univariable logistic regression, respectively. A total of 266 patients with incident AAD were enrolled: 84 patients with OHCA, 137 women [n = 137], and 164 patients with type A AAD. The crude and age-adjusted incidence of AAD was 16.2 and 14.3/100,000 person-years, respectively. The incidence of AAD was comparable by sex (men, 16.7/100,000 person-years; women, 15.7/100,000 person-years; incidence rate ratio: 0.94; 95% CI: 0.74-1.20; Women had a higher incidence of AAD presenting as prehospital death than men.
Sections du résumé
Background
UNASSIGNED
Acute aortic dissection (AAD) often leads to out-of-hospital cardiac arrest (OHCA) and death before hospital arrival.
Objectives
UNASSIGNED
The purpose of this study was to investigate differences in AAD incidence by sex.
Methods
UNASSIGNED
A population-based study in a city with 121,180 residents was conducted using postmortem computed tomography data to identify patients with AAD who died before hospital arrival in 2008-2020. The incidence rate ratio and odds ratio were estimated using Poisson regression and univariable logistic regression, respectively.
Results
UNASSIGNED
A total of 266 patients with incident AAD were enrolled: 84 patients with OHCA, 137 women [n = 137], and 164 patients with type A AAD. The crude and age-adjusted incidence of AAD was 16.2 and 14.3/100,000 person-years, respectively. The incidence of AAD was comparable by sex (men, 16.7/100,000 person-years; women, 15.7/100,000 person-years; incidence rate ratio: 0.94; 95% CI: 0.74-1.20;
Conclusions
UNASSIGNED
Women had a higher incidence of AAD presenting as prehospital death than men.
Identifiants
pubmed: 38938331
doi: 10.1016/j.jacadv.2023.100623
pii: S2772-963X(23)00594-X
pmc: PMC11198350
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100623Informations de copyright
© 2023 The Authors.
Déclaration de conflit d'intérêts
This work was supported in part by the 10.13039/100007449Takeda Science Foundation, the 10.13039/100015639Japan Cardiovascular Research Foundation, and 10.13039/501100001691JSPS KAKENHI Grant Number 22K16077. The authors have reported that they have no relationships relevant to the contents of this paper to disclose.