Digital Health Programs to Reduce Readmissions in Coronary Artery Disease: A Systematic Review and Meta-Analysis.

Background

The use of mobile health (mHealth, wireless communication devices, and/or software technologies) in health care delivery has increased rapidly in recent years. Their integration into disease management programs (DMPs) has tremendous potential to improve outcomes for patients with coronary artery disease (CAD), yet a more robust evaluation of the evidence is required.

Objectives

The purpose of this study was to undertake a systematic review and meta-analysis of mHealth-enabled DMPs to determine their effectiveness in reducing readmissions and mortality in patients with CAD.

Methods

We systematically searched English language studies from January 1, 2007, to August 3, 2021, in multiple databases. Studies comparing mHealth-enabled DMPs with standard DMPs without mHealth were included if they had a minimum 30-day follow-up for at least one of all-cause or cardiovascular-related mortality, readmissions, or major adverse cardiovascular events.

Results

Of the 3,411 references from our search, 155 full-text studies were assessed for eligibility, and data were extracted from 18 publications. Pooled findings for all-cause readmissions (10 studies, n = 1,514) and cardiac-related readmissions (9 studies, n = 1,009) indicated that mHealth-enabled DMPs reduced all-cause (RR: 0.68; 95% CI: 0.50-0.91) and cardiac-related hospitalizations (RR: 0.55; 95% CI: 0.44-0.68) and emergency department visits (RR: 0.37; 95% CI: 0.26-0.54) compared to DMPs without mHealth. There was no significant reduction for mortality outcomes (RR: 1.72; 95% CI: 0.64-4.64) or major adverse cardiovascular events (RR: 0.68; 95% CI: 0.40-1.15).

Conclusions

DMPs integrated with mHealth should be considered an effective intervention for better outcomes in patients with CAD.

Informations de copyright

© 2023 The Authors.

Déclaration de conflit d'intérêts

Mr Braver has received a postgraduate research scholarship from the University of Melbourne and the Baker Institute. Associate Professor Carrington has received an endowed fellowship in the Cardiology Center of Excellence from Filippo and Maria Casella. Supported in part by 10.13039/501100000925National Health and Medical Research Council (NHMRC) funding for the Center of Research Excellence in Digital Technology to Transform Chronic Disease Outcomes (APP 1170937) awarded to Dr Oldenburg. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.