Biventricular Repair in Borderline Left Hearts: Insights From Cardiac Magnetic Resonance Imaging.

borderline left heart left ventricle hypoplasia magnetic resonance imaging

Journal

JACC. Advances
ISSN: 2772-963X
Titre abrégé: JACC Adv
Pays: United States
ID NLM: 9918419284106676

Informations de publication

Date de publication:
Aug 2022
Historique:
received: 01 02 2022
revised: 03 07 2022
accepted: 04 07 2022
medline: 26 8 2022
pubmed: 26 8 2022
entrez: 28 6 2024
Statut: epublish

Résumé

Cardiac magnetic resonance imaging (CMR) may augment 2-dimensional (2D) echocardiography in decision-making for biventricular repair in borderline hypoplastic left hearts. This study evaluates: 1) the relationship between 2D echocardiography and CMR; 2) imaging variables affecting assignment to biventricular vs non-biventricular management; and 3) variables affecting transplant-free biventricular survival. We reviewed clinical, echocardiographic, and CMR data in 67 infants, including CMR-determined ascending aortic (AAo) flow and comparable left ventricular end-diastolic volume indexed (LVEDVi) by 2D-echocardiography and CMR. Treatment assignment to biventricular repair was either direct (BV, n = 45) or with a bridging hybrid procedure (H1-BV, n = 12). Echocardiographic LVEDVi was <20 mL/m Historical 2D echocardiographic criteria would have precluded many patients from successful biventricular repair. AAo flow, an integrative index of left heart performance, was important in assigning patients to a biventricular circulation and affected survival. Biventricular survival was strongly associated with the need for aortic coarctation repair.

Sections du résumé

Background UNASSIGNED
Cardiac magnetic resonance imaging (CMR) may augment 2-dimensional (2D) echocardiography in decision-making for biventricular repair in borderline hypoplastic left hearts.
Objectives UNASSIGNED
This study evaluates: 1) the relationship between 2D echocardiography and CMR; 2) imaging variables affecting assignment to biventricular vs non-biventricular management; and 3) variables affecting transplant-free biventricular survival.
Methods UNASSIGNED
We reviewed clinical, echocardiographic, and CMR data in 67 infants, including CMR-determined ascending aortic (AAo) flow and comparable left ventricular end-diastolic volume indexed (LVEDVi) by 2D-echocardiography and CMR.
Results UNASSIGNED
Treatment assignment to biventricular repair was either direct (BV, n = 45) or with a bridging hybrid procedure (H1-BV, n = 12). Echocardiographic LVEDVi was <20 mL/m
Conclusions UNASSIGNED
Historical 2D echocardiographic criteria would have precluded many patients from successful biventricular repair. AAo flow, an integrative index of left heart performance, was important in assigning patients to a biventricular circulation and affected survival. Biventricular survival was strongly associated with the need for aortic coarctation repair.

Identifiants

pubmed: 38938401
doi: 10.1016/j.jacadv.2022.100066
pii: S2772-963X(22)00071-0
pmc: PMC11198440
doi:

Types de publication

Journal Article

Langues

eng

Pagination

100066

Informations de copyright

© 2022 The Authors.

Déclaration de conflit d'intérêts

Dr Chaturvedi is supported by the Ted Rogers Centre for Heart Research, Toronto. The authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Auteurs

Sok-Leng Kang (SL)

The Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto School of Medicine, Toronto, Ontario, Canada.

Rajiv R Chaturvedi (RR)

The Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto School of Medicine, Toronto, Ontario, Canada.

Andrea Wan (A)

The Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto School of Medicine, Toronto, Ontario, Canada.

Kenneth Cheung (K)

Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto School of Medicine, Toronto, Ontario, Canada.

Christoph Haller (C)

The Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto School of Medicine, Toronto, Ontario, Canada.

Alison Howell (A)

The Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto School of Medicine, Toronto, Ontario, Canada.

David J Barron (DJ)

The Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto School of Medicine, Toronto, Ontario, Canada.

Mike Seed (M)

The Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto School of Medicine, Toronto, Ontario, Canada.
Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto School of Medicine, Toronto, Ontario, Canada.

Kyong-Jin Lee (KJ)

Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California, USA.

Classifications MeSH