Cardiac Magnetic Resonance Imaging in COVID-19 Vaccine-Associated Myocarditis Compared With Classical Myocarditis.

COVID-19 vaccination MRI myocarditis

Journal

JACC. Advances
ISSN: 2772-963X
Titre abrégé: JACC Adv
Pays: United States
ID NLM: 9918419284106676

Informations de publication

Date de publication:
Dec 2023
Historique:
received: 06 03 2023
revised: 26 07 2023
accepted: 01 09 2023
medline: 28 6 2024
pubmed: 28 6 2024
entrez: 28 6 2024
Statut: epublish

Résumé

Studies comparing COVID-19 vaccine-associated and classical myocarditis (CM) are lacking. The purpose of this study was to compare cardiac magnetic resonance (CMR) imaging findings and short-term clinical outcomes in patients with messenger RNA COVID-19 postvaccination myocarditis (PVM) and CM. This was a retrospective study of patients with myocarditis: 31 with PVM and 46 with CM. Patients underwent a CMR protocol scan including T1 and T2 sequences. Late gadolinium enhancement (LGE) was expressed as percentage of left ventricular myocardial mass and the extracellular volume was calculated based on precontrast and postcontrast T1 images. Clinical outcomes included heart failure hospitalizations and mortality. Study patients were predominantly male (81% in PVM vs 89% in CM, Our study shows similar CMR imaging findings and short-term outcomes in PVM and CM, although PVM was associated with milder myocardial abnormalities and more frequent pericardial involvement.

Sections du résumé

Background UNASSIGNED
Studies comparing COVID-19 vaccine-associated and classical myocarditis (CM) are lacking.
Objectives UNASSIGNED
The purpose of this study was to compare cardiac magnetic resonance (CMR) imaging findings and short-term clinical outcomes in patients with messenger RNA COVID-19 postvaccination myocarditis (PVM) and CM.
Methods UNASSIGNED
This was a retrospective study of patients with myocarditis: 31 with PVM and 46 with CM. Patients underwent a CMR protocol scan including T1 and T2 sequences. Late gadolinium enhancement (LGE) was expressed as percentage of left ventricular myocardial mass and the extracellular volume was calculated based on precontrast and postcontrast T1 images. Clinical outcomes included heart failure hospitalizations and mortality.
Results UNASSIGNED
Study patients were predominantly male (81% in PVM vs 89% in CM,
Conclusions UNASSIGNED
Our study shows similar CMR imaging findings and short-term outcomes in PVM and CM, although PVM was associated with milder myocardial abnormalities and more frequent pericardial involvement.

Identifiants

pubmed: 38938491
doi: 10.1016/j.jacadv.2023.100726
pii: S2772-963X(23)00749-4
pmc: PMC11198221
doi:

Types de publication

Journal Article

Langues

eng

Pagination

100726

Informations de copyright

© 2023 The Authors.

Déclaration de conflit d'intérêts

The authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Auteurs

Yaron Aviv (Y)

Department of Cardiology, Rabin Medical Center, Petah Tikva, Israel.
Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.

Arthur Shiyovich (A)

Department of Cardiology, Rabin Medical Center, Petah Tikva, Israel.
Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.

Ygal Plakht (Y)

Faculty of Health Sciences, Department of Nursing, Soroka University Medical Center, Ben-Gurion University, Beer-Sheva, Israel.

Guy Witberg (G)

Department of Cardiology, Rabin Medical Center, Petah Tikva, Israel.
Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.

Maya Weissman (M)

Department of Cardiology, Rabin Medical Center, Petah Tikva, Israel.
Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.

Gideon Shafir (G)

Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
Department of Radiology, Rabin Medical Center, Petah Tikva, Israel.

Ran Kornowski (R)

Department of Cardiology, Rabin Medical Center, Petah Tikva, Israel.
Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.

Ashraf Hamdan (A)

Department of Cardiology, Rabin Medical Center, Petah Tikva, Israel.
Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.

Classifications MeSH