TRPC3 signalling contributes to the biogenesis of extracellular vesicles.
Extracellular vesicles
TRPC3
calcium
exosomes
histamine
ovarian cancer
Journal
Journal of extracellular biology
ISSN: 2768-2811
Titre abrégé: J Extracell Biol
Pays: United States
ID NLM: 9918382980506676
Informations de publication
Date de publication:
Jan 2024
Jan 2024
Historique:
received:
18
07
2023
revised:
29
10
2023
accepted:
08
12
2023
medline:
28
6
2024
pubmed:
28
6
2024
entrez:
28
6
2024
Statut:
epublish
Résumé
Extracellular vesicles (EVs) contribute to a wide range of pathological processes including cancer progression, yet the molecular mechanisms underlying their biogenesis remain incompletely characterized. The development of tetraspanin-based pHluorin reporters has enabled the real-time analysis of EV release at the plasma membrane. Here, we employed CD81-pHluorin to investigate mechanisms of EV release in ovarian cancer (OC) cells and report a novel role for the Ca
Identifiants
pubmed: 38938673
doi: 10.1002/jex2.132
pii: JEX2132
pmc: PMC11080740
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e132Informations de copyright
© 2023 The Authors. Journal of Extracellular Biology published by Wiley Periodicals LLC on behalf of International Society for Extracellular Vesicles.
Déclaration de conflit d'intérêts
The authors report no conflict of interest.