Design and deployment of the STEEER-AF trial to evaluate and improve guideline adherence: A cluster-randomised trial by the European Society of Cardiology and European Heart Rhythm Association.
Atrial fibrillation
Guideline adherence
rhythm control
stroke prevention
trial
Journal
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
ISSN: 1532-2092
Titre abrégé: Europace
Pays: England
ID NLM: 100883649
Informations de publication
Date de publication:
28 Jun 2024
28 Jun 2024
Historique:
received:
13
05
2024
accepted:
19
06
2024
medline:
28
6
2024
pubmed:
28
6
2024
entrez:
28
6
2024
Statut:
aheadofprint
Résumé
To describe the rationale, design, delivery and baseline characteristics of STEEER-AF (Stroke prevention and rhythm control Treatment: Evaluation of an Educational programme of the European Society of Cardiology [ESC] in a cluster-Randomised trial in patients with Atrial Fibrillation). STEEER-AF is a pragmatic trial designed to objectively and robustly determine whether guidelines are adhered to in routine practice, and evaluate a targeted educational programme for healthcare professionals. Seventy centres were randomised in 6 countries (France, Germany, Italy, Poland, Spain and United Kingdom; 2022-2023). STEEER-AF centres recruited 1732 patients with a diagnosis of atrial fibrillation (AF), with mean age 68.9 years (SD 11.7), CHA2DS2-VASc score 3.2 (SD 1.8) and 647 (37%) women. 843 patients (49%) were in AF and 760 (44%) in sinus rhythm at enrolment. Oral anticoagulant therapy was prescribed in 1,543 patients (89%), with the majority receiving direct oral anticoagulants (1,378; 89%). Previous cardioversion, antiarrhythmic drug therapy or ablation was recorded in 836 patients (48.3%). 551 patients (31.8%) were currently receiving an antiarrhythmic drug, and 446 (25.8%) were scheduled to receive a future cardioversion or ablation. The educational programme engaged 195 healthcare professionals across centres randomised to the intervention group, consisting of bespoke interactive online learning and reinforcement activities, supported by national expert trainers. The STEEER-AF trial was successfully deployed across six European countries to investigate guideline adherence in real-world practice, and evaluate if a structured educational programme for healthcare professionals can improve patient-level care. Clinicaltrials.gov NCT04396418.
Identifiants
pubmed: 38940494
pii: 7701021
doi: 10.1093/europace/euae178
pii:
doi:
Banques de données
ClinicalTrials.gov
['NCT04396418']
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Investigateurs
Yann Allali
(Y)
Asgher Champsi
(A)
Thomas Deneke
(T)
Kaitlyn Greeley
(K)
Benoît Guy-Moyat
(B)
Mikael Laredo
(M)
Alastair Mobley
(A)
Maximina Ventura
(M)
Mary Stanbury
(M)
Trudie Lobban
(T)
Thompson Robinson
(T)
Tatjana Potpara
(T)
Eloi Marijon
(E)
Pascal Defaye
(P)
Pierre Baudinaud
(P)
Simon Kochhaeuser
(S)
Ursula Rauch
(U)
Moritz F Sinner
(MF)
Marco Proietti
(M)
Igor Diemberger
(I)
Vincenzo Russo
(V)
Stanislaw Tubek
(S)
Piotr Buchta
(P)
Pawel Balsam
(P)
Eusebio García-Izquierdo
(E)
Ivo Roca Luque
(I)
Jose M Guerra
(JM)
Dewi Thomas
(D)
Afzal Sohaib
(A)
Mark J Davies
(MJ)
Olivier Piot
(O)
William Escande
(W)
Christian De Chillou
(C)
Maxime De Guillebon
(M)
Frédéric Anselme
(F)
Andrea Cianci
(A)
Rodrigue Garcia
(R)
Philippe Maury
(P)
Dominique Pavin
(D)
Estelle Gandjbakhch
(E)
Frédéric Sacher
(F)
Karim Hasni
(K)
Fabien Garnier
(F)
Charles Guenancia
(C)
Nicolas Lellouche
(N)
Stephan Willems
(S)
Martin Borlich
(M)
Andreas Metzner
(A)
Hans-Holger Ebert
(HH)
Dong-In Shin
(DI)
David Duncker
(D)
Stefan G Spitzer
(SG)
Peter Nordbeck
(P)
Roland R Tilz
(RR)
Andrea Mazza
(A)
Cinzia Valzania
(C)
Margherita Padeletti
(M)
Matteo Bertini
(M)
Giuseppe Boriani
(G)
Jacopo F Imberti
(JF)
Stefano Fumagalli
(S)
Antonio Rapacciuolo
(A)
Monika Lica Gorzynska
(M)
Adam Gorlo
(A)
Marcin Kostkiewicz
(M)
Grzegorz Sobieszek
(G)
Andrzej S Skrzyń Ski
(AS)
Robert Gajda
(R)
Hanna Wilk-Manowiec
(H)
Jaroslaw Blicharz
(J)
Wiktor K Gmiń Ski
(WK)
Tomasz Czerski
(T)
Felipe Bisbal
(F)
Ignasi Anguera
(I)
Teresa Lozano
(T)
Joaquin Osca
(J)
Jose L Merino
(JL)
Naiara Calvo
(N)
Juan Fernández-Armenta
(J)
Juan Acosta
(J)
Nuria Rivas-Gandara
(N)
Pilar Cabanas
(P)
Emilce Trucco
(E)
Richard Bond
(R)
Richard Ang
(R)
Shawn A A Morais
(SAA)
Fu Siong Ng
(F)
Mattew G D Bates
(MGD)
Michala Pedersen
(M)
Daniel T Raine
(DT)
Manish Kalla
(M)
Matthew J Lovell
(MJ)
Malcolm Finlay
(M)
Arif Hasan Bhuiyan
(A)
Norman Qureshi
(N)
Hein Heidbuchel
(H)
Wolfram Döhner
(W)
Bernard Iung
(B)
Susanna Price
(S)
Helmut Pürerfellner
(H)
Barbara Casadei
(B)
Paulus Kirchhof
(P)
Alex R Lyon
(AR)
Winston Banya
(W)
Robert Hatala
(R)
Pekka Raatikainen
(P)
Informations de copyright
© The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology.