Antioxidant and neurodevelopmental gene polymorphisms in prematurely born individuals influence hypoxia-related oxidative stress.
Humans
Oxidative Stress
/ genetics
Male
Hypoxia
/ genetics
Antioxidants
/ metabolism
Polymorphism, Single Nucleotide
Young Adult
Infant, Newborn
Glutathione Peroxidase GPX1
Hypoxia-Inducible Factor 1, alpha Subunit
/ genetics
Catalase
/ genetics
Adult
Glutathione Peroxidase
/ genetics
Infant, Premature
Nitrites
/ metabolism
Malondialdehyde
/ metabolism
Tyrosine
/ genetics
Premature Birth
/ genetics
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
28 Jun 2024
28 Jun 2024
Historique:
received:
04
10
2023
accepted:
21
06
2024
medline:
29
6
2024
pubmed:
29
6
2024
entrez:
28
6
2024
Statut:
epublish
Résumé
Preterm born (PTB) infants are at risk for injuries related to oxidative stress. We investigated the association between antioxidant and neurodevelopmental gene polymorphisms and oxidative stress parameters in PTB male young adults and their term-born counterparts at rest and during exercise. Healthy young PTB (N = 22) and full-term (N = 15) males underwent graded exercise tests in normobaric normoxic (F
Identifiants
pubmed: 38942829
doi: 10.1038/s41598-024-65647-4
pii: 10.1038/s41598-024-65647-4
doi:
Substances chimiques
Antioxidants
0
Glutathione Peroxidase GPX1
EC 1.11.1.9
Hypoxia-Inducible Factor 1, alpha Subunit
0
GPX1 protein, human
EC 1.11.1.9
Catalase
EC 1.11.1.6
CAT protein, human
EC 1.11.1.6
Glutathione Peroxidase
EC 1.11.1.9
HIF1A protein, human
0
Nitrites
0
Malondialdehyde
4Y8F71G49Q
3-nitrotyrosine
3604-79-3
Tyrosine
42HK56048U
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
14956Informations de copyright
© 2024. The Author(s).
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