Immersive virtual reality as a novel approach to investigate the association between adverse events and adolescent paranoid ideation.
Adolescence
Adversity
Aetiology
Bullying
Paranoid ideation
Virtual reality
Journal
Social psychiatry and psychiatric epidemiology
ISSN: 1433-9285
Titre abrégé: Soc Psychiatry Psychiatr Epidemiol
Pays: Germany
ID NLM: 8804358
Informations de publication
Date de publication:
28 Jun 2024
28 Jun 2024
Historique:
received:
04
02
2023
accepted:
10
06
2024
medline:
29
6
2024
pubmed:
29
6
2024
entrez:
28
6
2024
Statut:
aheadofprint
Résumé
Paranoid ideation is common among adolescents, yet little is known about the precursors. Using a novel immersive virtual reality (VR) paradigm, we tested whether experiences of bullying, and other interpersonal/threatening events, are associated with paranoid ideation to a greater degree than other types of (i) non-interpersonal events or (ii) adverse childhood experiences. Self-reported exposure to adverse life events and bullying was collected on 481 adolescents, aged 11-15. We used mixed effects (multilevel) linear regression to estimate the magnitude of associations between risk factors and paranoid ideation, assessed by means of adolescents' reactions to ambiguously behaving avatars in a VR school canteen, adjusting for putative confounders (gender, year group, ethnicity, free school meal status, place of birth, family mental health problems). Lifetime exposure to interpersonal/threatening events, but not non-interpersonal events or adverse circumstances, was associated with higher levels of state paranoid ideation, with further evidence that the effect was cumulative (1 type: ϐ Our data suggest a degree of specificity for adversities involving interpersonal threat or hostility, i.e. those that involve unwanted interference and/or attempted control of an individual's personal boundaries being associated with heightened levels of state paranoid ideation among adolescents.
Identifiants
pubmed: 38942902
doi: 10.1007/s00127-024-02701-6
pii: 10.1007/s00127-024-02701-6
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : European Research Council
ID : REACH 648837
Pays : International
Organisme : ESRC Centre for Society and Mental Health, King's College London
ID : ES/S012567/1
Informations de copyright
© 2024. The Author(s).
Références
Kilford EJ, Garrett E, Blakemore S-J (2016) The development of social cognition in adolescence: an integrated perspective. Neurosci Biobehav Rev 70:106–120
pubmed: 27545755
doi: 10.1016/j.neubiorev.2016.08.016
Steinberg L (2005) Cognitive and affective development in adolescence. Trends Cogn Sci 9:69–74
pubmed: 15668099
doi: 10.1016/j.tics.2004.12.005
Ronald A, Sieradzka D, Cardno AG, Haworth CM, McGuire P, Freeman D (2013) Characterization of psychotic experiences in adolescence using the specific psychotic experiences questionnaire: findings from a study of 5000 16-year-old twins. Schizophr Bull 40:868–877
pubmed: 24062593
pmcid: 4059437
doi: 10.1093/schbul/sbt106
Bird JC, Evans R, Waite F, Loe BS, Freeman D (2019) Adolescent paranoia: prevalence, structure, and causal mechanisms. Schizophr Bull 45:1134–1142
pubmed: 30534970
doi: 10.1093/schbul/sby180
Fisher H, Caspi A, Poulton R et al (2013) Specificity of childhood psychotic symptoms for predicting schizophrenia by 38 years of age: a birth cohort study. Psychol Med 43:2077–2086
pubmed: 23302254
pmcid: 3758773
doi: 10.1017/S0033291712003091
Campbell ML, Morrison AP (2007) The relationship between bullying, psychotic-like experiences and appraisals in 14–16-year olds. Behav Res Ther 45:1579–1591
pubmed: 17229400
doi: 10.1016/j.brat.2006.11.009
Jack AH, Egan V (2018) Childhood bullying, paranoid thinking and the misappraisal of social threat: trouble at school. School Mental Health 10:26–34
pubmed: 29503671
doi: 10.1007/s12310-017-9238-z
Bird JC, Freeman D, Waite F (2022) The journey of adolescent paranoia: a qualitative study with patients attending child and adolescent mental health services. Psychol Psychother 95:508–524
pubmed: 35150474
pmcid: 9304248
doi: 10.1111/papt.12385
Freeman D, P Garety (2014) Advances in understanding and treating persecutory delusions: a review. Soc Psychiatry Psychiatr Epidemiol 49:1179–1189
pubmed: 25005465
pmcid: 4108844
doi: 10.1007/s00127-014-0928-7
Finkelhor D, Ormrod R, Turner H, Hamby SL (2005) The victimization of children and youth: a comprehensive, national survey. Child Maltreat 10:5–25
pubmed: 15611323
doi: 10.1177/1077559504271287
Turner HA, Finkelhor D, Ormrod R (2006) The effect of lifetime victimization on the mental health of children and adolescents. Soc Sci Med 62:13–27
pubmed: 16002198
doi: 10.1016/j.socscimed.2005.05.030
Arseneault L, Cannon M, Fisher HL, Polanczyk G, Moffitt TE, Caspi A (2011) Childhood trauma and children’s emerging psychotic symptoms: a genetically sensitive longitudinal cohort study. Am J Psychiatry 168:65–72
pubmed: 20952460
doi: 10.1176/appi.ajp.2010.10040567
Moriyama TS, Drukker M, Gadelha A et al (2018) The association between psychotic experiences and traumatic life events: the role of the intention to harm. Psychol Med 48:2235–2246
pubmed: 29331167
doi: 10.1017/S0033291717003762
Newbury J, Arseneault L, Caspi A, Moffitt TE, Odgers CL, Fisher HL (2018) Cumulative effects of neighborhood social adversity and personal crime victimization on adolescent psychotic experiences. Schizophr Bull 44:348–358
pubmed: 28535284
doi: 10.1093/schbul/sbx060
Karcher NR, Niendam TA, Barch DM (2020) Adverse childhood experiences and psychotic-like experiences are associated above and beyond shared correlates: findings from the adolescent brain cognitive development study. Schizophr Res 222:235–242
pubmed: 32522466
pmcid: 7572890
doi: 10.1016/j.schres.2020.05.045
Vargas T, Damme KS, Osborne KJ, Mittal VA (2022) Differentiating kinds of systemic stressors with relation to psychotic-like experiences in late childhood and early adolescence: the stimulation, discrepancy, and deprivation model of psychosis. Clin Psychol Sci 10:291–309
pubmed: 35402089
doi: 10.1177/21677026211016415
Valmaggia LR, Day F, Rus-Calafell M (2016) Using virtual reality to investigate psychological processes and mechanisms associated with the onset and maintenance of psychosis: a systematic review. Soc Psychiatry Psychiatr Epidemiol 51:921–936
pubmed: 27262562
doi: 10.1007/s00127-016-1245-0
Freeman D, Antley A, Ehlers A et al (2014) The use of immersive virtual reality (VR) to predict the occurrence 6 months later of paranoid thinking and posttraumatic stress symptoms assessed by self-report and interviewer methods: a study of individuals who have been physically assaulted. Psychol Assess 26:841–847
pubmed: 24708073
pmcid: 4151801
doi: 10.1037/a0036240
Freeman D, Pugh K, Antley A et al (2008) Virtual reality study of paranoid thinking in the general population. Br J Psychiatry 192:258–263
pubmed: 18378984
doi: 10.1192/bjp.bp.107.044677
Freeman D (2008) The assessment of persecutory ideation. In: Freeman D, Bentall R, Garety P (eds) Persecutory delusions: Assessment, theory and treatment. Oxford University Press, Oxford, United Kingdom, pp 23–52
doi: 10.1093/med:psych/9780199206315.003.0002
Shakoor S, McGuire P, Cardno AG, Freeman D, Plomin R, Ronald A (2015) A shared genetic propensity underlies experiences of bullying victimization in late childhood and self-rated paranoid thinking in adolescence. Schizophr Bull 41:754–763
pubmed: 25323579
doi: 10.1093/schbul/sbu142
Veldkamp SA, Boomsma DI, de Zeeuw EL et al (2019) Genetic and environmental influences on different forms of bullying perpetration, bullying victimization, and their co-occurrence. Behav Genet 49:432–443
pubmed: 31502010
pmcid: 6768918
doi: 10.1007/s10519-019-09968-5
Knowles G, Gayer-Anderson C, Beards S et al (2021) Mental Distress among Young people in Inner-Cities: the Resilience, ethnicity and AdolesCent Mental Health (REACH) study. J Epidemiol Community Health 75:515–522
pubmed: 33558428
doi: 10.1136/jech-2020-214315
Olweus D (1996) Revised Olweus bully/victim questionnaire. Br J Educ Psychol
Bhui KS, Lenguerrand E, Maynard MJ, Stansfeld SA, Harding S (2012) Does cultural integration explain a mental health advantage for adolescents? Int J Epidemiol 41:791–802
pubmed: 22366123
pmcid: 3396315
doi: 10.1093/ije/dys007
Cullen AE, Fisher HL, Roberts RE, Pariante CM, Laurens KR (2014) Daily stressors and negative life events in children at elevated risk of developing schizophrenia. Br J Psychiatry 204:354–360
pubmed: 24627296
doi: 10.1192/bjp.bp.113.127001
Nilsson D, Gustafsson PE, Larsson JL, Svedin CG (2010) Evaluation of the Linköping youth life experience scale. J Nerv Ment Dis 198:768–774
pubmed: 20921869
doi: 10.1097/NMD.0b013e3181f4acb6
Freeman D, Pugh K, Green C, Valmaggia L, Dunn G, Garety P (2007) A measure of state persecutory ideation for experimental studies. J Nerv Ment Dis 195:781–784
pubmed: 17984781
doi: 10.1097/NMD.0b013e318145a0a9
Riches S, Garety P, Rus-Calafell M et al (2019) Using virtual reality to assess associations between paranoid ideation and components of social performance: a pilot validation study. Cyberpsychol Behav Soc Netw 22:51–59
pubmed: 30346808
doi: 10.1089/cyber.2017.0656
Freeman D, Garety P, Bebbington P et al (2005) The psychology of persecutory ideation II: a virtual reality experimental study. J Nerv Ment Dis 193:309–315
pubmed: 15870614
doi: 10.1097/01.nmd.0000161686.53245.70
Allen P, Freeman D, McGuire P (2007) Slow habituation of arousal associated with psychosis proneness. Psychol Med 37:577–582
pubmed: 17176503
doi: 10.1017/S0033291706009615
Castro MN, Vigo DE, Weidema H et al (2008) Heart rate variability response to mental arithmetic stress in patients with schizophrenia: autonomic response to stress in schizophrenia. Schizophr Res 99:294–303
pubmed: 17913466
doi: 10.1016/j.schres.2007.08.025
Veling W, Brinkman WP, Dorrestijn E, Van Der Gaag M (2014) Virtual reality experiments linking social environment and psychosis: a pilot study. Cyberpsychol Behav Soc Netw 17:191–195
pubmed: 23992475
doi: 10.1089/cyber.2012.0497
Van Os J, Linscott RJ, Myin-Germeys I, Delespaul P, Krabbendam LJPM (2009) A systematic review and meta-analysis of the psychosis continuum: evidence for a psychosis proneness–persistence–impairment model of psychotic disorder. Psychol med 39:179–195
pubmed: 18606047
doi: 10.1017/S0033291708003814
Cornell D, Bandyopadhyay S (2009) The assessment of bullying. Int Handb School Bullying 265–276
Przybylski AK, Bowes L (2017) Cyberbullying and adolescent well-being in England: a population-based cross-sectional study. Lancet Child Adolesc Health 1:19–26
pubmed: 30169221
doi: 10.1016/S2352-4642(17)30011-1
Masillo A, Valmaggia LR, Saba R et al (2019) Interpersonal sensitivity, bullying victimization and paranoid ideation among help-seeking adolescents and young adults. Early Interv Psychiatry 13:57–63
pubmed: 28560857
doi: 10.1111/eip.12447
Bird JC, Waite F, Rowsell E, Fergusson EC, Freeman D (2017) Cognitive, affective, and social factors maintaining paranoia in adolescents with mental health problems: a longitudinal study. Psychiatr Res 257:34–39
doi: 10.1016/j.psychres.2017.07.023
Kim S, Colwell SR, Kata A, Boyle MH, Georgiades K (2018) Cyberbullying victimization and adolescent mental health: evidence of differential effects by sex and mental health problem type. J Youth Adolesc 47:661–672
pubmed: 28434092
doi: 10.1007/s10964-017-0678-4
Beards S, Fisher HL, Gayer-Anderson C et al (2020) Threatening life events and difficulties and psychotic disorder. Schizophr Bull 46:814–822
pubmed: 32047940
pmcid: 7342097
doi: 10.1093/schbul/sbaa005
Benenson JF, Markovits H, Hultgren B, Nguyen T, Bullock G, Wrangham R (2013) Social exclusion: more important to human females than males. PLoS ONE 8:e55851
pubmed: 23405221
pmcid: 3566112
doi: 10.1371/journal.pone.0055851
Garety PA, Kuipers E, Fowler D, Freeman D, Bebbington P (2001) A cognitive model of the positive symptoms of psychosis. Psychol Med 31:189–195
pubmed: 11232907
doi: 10.1017/S0033291701003312
Shakoor S, Zavos HM, Haworth CM et al (2016) Association between stressful life events and psychotic experiences in adolescence: evidence for gene–environment correlations. Br J Psychiatry 208:532–538
pubmed: 27056622
pmcid: 4887723
doi: 10.1192/bjp.bp.114.159079
Taylor MJ, Freeman D, Lundström S, Larsson H, Ronald A (2022) Heritability of psychotic experiences in adolescents and interaction with environmental risk. JAMA Psychiatr 79:889–897
doi: 10.1001/jamapsychiatry.2022.1947
Saarinen A, Granö N, Hintsanen M, Lehtimäki T, Cloninger CR, Keltikangas-Järvinen L (2022) Bidirectional pathways between psychosocial risk factors and paranoid ideation in a general nonclinical population. Dev Psychopathol 34:421–430
pubmed: 33084551
doi: 10.1017/S0954579420001030