Detectability of Breast Cancer in Dedicated Breast CT Compared With Mammography Dependent on Breast Density.
Journal
Investigative radiology
ISSN: 1536-0210
Titre abrégé: Invest Radiol
Pays: United States
ID NLM: 0045377
Informations de publication
Date de publication:
02 Jul 2024
02 Jul 2024
Historique:
pubmed:
1
7
2024
medline:
1
7
2024
entrez:
1
7
2024
Statut:
aheadofprint
Résumé
To evaluate the detectability of non-contrast-enhanced and contrast-enhanced spiral breast computed tomography ([non]-CE-SBCT) compared with mammography. Secondary objectives are to determine detectability depending on breast density and to evaluate appearance of breast malignancies according to BI-RADS descriptors. This retrospective institutional review board-approved study included 90 women with 105 biopsy-proven malignant breast lesions. Breast density, BI-RADS descriptors, and detectability were evaluated by 2 independent readers. Diagnostic confidence was rated on a 4-point Likert scale. For readers 1 and 2, detectability was 83.8% and 80.0% for mammography, 99.1% and 99.1% for CE-SBCT ( P < 0.05), and 66.7% and 61.9% for non-CE-SBCT ( P < 0.05). With both readers, detectability in CE-SBCT was high for density A/B/C/D (both 100%/100%/100%/87.5%). Detectability of readers declined with increasing density for mammography (density A = 100%, B = 89.1% and 95.1%, C = 73.1%, D = 50.0% and 71.4%; P < 0.05) and for non-CE-SBCT (density A = 87.5% and 90.7%, B = 65.5% and 69.1%, C = 54.8% and 60.0%, D = 37.5%; P < 0.05). Mass lesions were detected with CT as often as with mammography, whereas architectural distortions and microcalcifications were detected less often with SBCT. Diagnostic confidence was very high or high in 97.2% for CE-SBCT, in 74.1% for non-CE-SBCT, and in 81.4% for mammography. Detectability and diagnostic confidence were very high in CE-SBCT, regardless of breast density. The detectability of non-CE-SBCT was lower than that of mammography and declined with increasing breast density.
Identifiants
pubmed: 38949016
doi: 10.1097/RLI.0000000000001105
pii: 00004424-990000000-00229
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of interest and sources of funding: M.W. is part of the speaker bureau of Siemens Healthineers AG. E.W. is part of the speaker bureau of Siemens Healthineers AG and is a member of the advisory board of AB-CT and of Becton Dickinson GmbH. For the remaining authors, none were declared.
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