Wnt/β-catenin signaling within multiple cell types dependent upon

Biological sciences Developmental biology Natural sciences

Journal

iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038

Informations de publication

Date de publication:
21 Jun 2024
Historique:
received: 23 02 2023
revised: 08 03 2024
accepted: 23 05 2024
medline: 2 7 2024
pubmed: 2 7 2024
entrez: 2 7 2024
Statut: epublish

Résumé

The gut epithelium is subject to constant renewal, a process reliant upon intestinal stem cell (ISC) proliferation that is driven by Wnt/β-catenin signaling. Despite the importance of Wnt signaling within ISCs, the relevance of Wnt signaling within other gut cell types and the underlying mechanisms that modulate Wnt signaling in these contexts remain incompletely understood. Using challenge of the

Identifiants

DOI: 10.1016/j.isci.2024.110113 PMID: 38952681 PMC: PMC11215309
pubmed: 38952681
doi: 10.1016/j.isci.2024.110113
pii: S2589-0042(24)01338-5
pmc: PMC11215309
doi:

Types de publication

Journal Article

Langues

eng

Pagination

110113

Informations de copyright

© 2024 The Author(s).

Déclaration de conflit d'intérêts

The authors declare no competing interests.

Auteurs

Hongyan Sun (H)

Weill Institute for Cell & Molecular Biology, Cornell University, Ithaca, NY 14853, USA.

Adnan Shami Shah (A)

Weill Institute for Cell & Molecular Biology, Cornell University, Ithaca, NY 14853, USA.
Department of Chemistry & Chemical Biology, Cornell University, Ithaca, NY 14853, USA.

Din-Chi Chiu (DC)

Weill Institute for Cell & Molecular Biology, Cornell University, Ithaca, NY 14853, USA.
Department of Chemistry & Chemical Biology, Cornell University, Ithaca, NY 14853, USA.

Alessandro Bonfini (A)

Cornell Institute of Host Microbe Interactions and Disease, Department of Entomology, Cornell University, Ithaca, NY 14853, USA.
Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Haining 314400, P.R. China.
Edinburgh Medical School: Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, UK.

Nicolas Buchon (N)

Cornell Institute of Host Microbe Interactions and Disease, Department of Entomology, Cornell University, Ithaca, NY 14853, USA.

Jeremy M Baskin (JM)

Weill Institute for Cell & Molecular Biology, Cornell University, Ithaca, NY 14853, USA.
Department of Chemistry & Chemical Biology, Cornell University, Ithaca, NY 14853, USA.

Classifications MeSH