Secondary Hirata Syndrome in a Neonate: Practical Approach and Management.

Hirata insulin antibodies insulin autoimmune syndrome neonatal hypoglycemia neonate

Journal

JCEM case reports
ISSN: 2755-1520
Titre abrégé: JCEM Case Rep
Pays: England
ID NLM: 9918609886906676

Informations de publication

Date de publication:
Jul 2024
Historique:
received: 28 01 2024
medline: 2 7 2024
pubmed: 2 7 2024
entrez: 2 7 2024
Statut: epublish

Résumé

Hirata disease, also known as insulin autoimmune syndrome (IAS), is a rare cause of hypoglycemia, due to the presence of insulin autoantibodies (IAA) in the circulating blood. These antibodies are immunoglobulin G (IgG), making placental transfer to the fetus possible. To our knowledge, no reports of IAS have been previously described in the neonatal population. We present a case report of hypoglycemia due to a secondary IAS in a neonate and discuss the management and treatment of the disease.

Identifiants

DOI: 10.1210/jcemcr/luae109 PMID: 38952701 PMC: PMC11216324
pubmed: 38952701
doi: 10.1210/jcemcr/luae109
pii: luae109
pmc: PMC11216324
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Pagination

luae109

Informations de copyright

© The Author(s) 2024. Published by Oxford University Press on behalf of the Endocrine Society.

Auteurs

Alessandro Perri (A)

Department of Woman and Child Health Sciences, Child Health Area, University Hospital Agostino Gemelli, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Lazio, Italy.
ORCID: 0000-0002-8914-8639

Simona Fattore (S)

Department of Woman and Child Health Sciences, Child Health Area, University Hospital Agostino Gemelli, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Lazio, Italy.
ORCID: 0000-0002-2991-2068

Annamaria Sbordone (A)

Department of Woman and Child Health Sciences, Child Health Area, University Hospital Agostino Gemelli, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Lazio, Italy.

Luca Viti (L)

Diabetes Care Unit, Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.

Dario Pitocco (D)

Diabetes Care Unit, Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.

Giovanni Vento (G)

Department of Woman and Child Health Sciences, Child Health Area, University Hospital Agostino Gemelli, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Lazio, Italy.
Department of Woman and Child Health Sciences, Child Health Area, Catholic University of Sacred Heart Seat of Rome, 00168 Rome, Lazio, Italy.

Classifications MeSH