Preoperative visualization of the greater occipital nerve with magnetic resonance imaging in candidates for occipital nerve decompression for headaches.
Decompression surgery
Headache surgery
MRI
Migraine surgery
Nerve
Nerve decompression
Neuralgia
Neuropathic pain
Occipital nerve
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
02 07 2024
02 07 2024
Historique:
received:
28
03
2024
accepted:
19
06
2024
medline:
3
7
2024
pubmed:
3
7
2024
entrez:
2
7
2024
Statut:
epublish
Résumé
Occipital nerve decompression is effective in reducing headache symptoms in select patients with migraine and occipital neuralgia. Eligibility for surgery relies on subjective symptoms and responses to nerve blocks and Onabotulinum toxin A (Botox) injections. No validated objective method exists for detecting occipital headache pathologies. The purpose of the study is to explore the potential of high-resolution Magnetic Resolution Imaging (MRI) in identifying greater occipital nerve (GON) pathologies in chronic headache patients. The MRI protocol included three sequences targeting fat-suppressed fluid-sensitive T2-weighted signals. Visualization of the GON involved generating 2-D image slices with sequential rotation to track the nerve course. Twelve patients underwent pre-surgical MRI assessment. MRI identified four main pathologies that were validated against intra-operative examination: GON entanglement by the occipital artery, increased nerve thickness and hyperintensity suggesting inflammation compared to the non-symptomatic contralateral side, early GON branching with rejoining at a distal point, and a connection between the GON and the lesser occipital nerve. MRI possesses the ability to visualize the GON and identify suspected trigger points associated with headache symptoms. This case series highlights MRI's potential to provide objective evidence of nerve pathology. Further research is warranted to establish MRI as a gold standard for diagnosing extracranial contributors in headaches.
Identifiants
pubmed: 38956162
doi: 10.1038/s41598-024-65334-4
pii: 10.1038/s41598-024-65334-4
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
15248Subventions
Organisme : Vanderbilt Institute for Clinical and Translational Research
ID : VR60350
Organisme : Plastic Surgery Foundation
ID : 941171
Informations de copyright
© 2024. The Author(s).
Références
Kemp, W. J. 3rd., Tubbs, R. S. & Cohen-Gadol, A. A. The innervation of the scalp: A comprehensive review including anatomy, pathology, and neurosurgical correlates. Surg. Neurol. Int. 2, 178. https://doi.org/10.4103/2152-7806.90699 (2011).
doi: 10.4103/2152-7806.90699
pubmed: 22276233
pmcid: 3262995
Barmherzig, R. & Kingston, W. Occipital neuralgia and cervicogenic headache: Diagnosis and management. Curr. Neurol. Neurosci. Rep. 19, 20. https://doi.org/10.1007/s11910-019-0937-8 (2019).
doi: 10.1007/s11910-019-0937-8
pubmed: 30888540
Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edn. Cephalalgia 38, 1–211 (2018). https://doi.org/10.1177/0333102417738202
Do, T. P., Hougaard, A., Dussor, G., Brennan, K. C. & Amin, F. M. Migraine attacks are of peripheral origin: the debate goes on. J. Headache Pain. 24, 3. https://doi.org/10.1186/s10194-022-01538-1 (2023).
doi: 10.1186/s10194-022-01538-1
pubmed: 36627561
pmcid: 9830833
Shevel, E. The extracranial vascular theory of migraine—A great story confirmed by the facts. Headache 51, 409–417. https://doi.org/10.1111/j.1526-4610.2011.01844.x (2011).
doi: 10.1111/j.1526-4610.2011.01844.x
pubmed: 21352215
Bartsch, T. & Goadsby, P. J. Stimulation of the greater occipital nerve induces increased central excitability of dural afferent input. Brain 125, 1496–1509. https://doi.org/10.1093/brain/awf166 (2002).
doi: 10.1093/brain/awf166
pubmed: 12077000
Bartsch, T. & Goadsby, P. J. The trigeminocervical complex and migraine: Current concepts and synthesis. Curr. Pain Headache Rep. 7, 371–376. https://doi.org/10.1007/s11916-003-0036-y (2003).
doi: 10.1007/s11916-003-0036-y
pubmed: 12946290
Goadsby, P. J. et al. Pathophysiology of migraine: A disorder of sensory processing. Physiol. Rev. 97, 553–622. https://doi.org/10.1152/physrev.00034.2015 (2017).
doi: 10.1152/physrev.00034.2015
pubmed: 28179394
pmcid: 5539409
Steiner, T. J. & Stovner, L. J. Global epidemiology of migraine and its implications for public health and health policy. Nat. Rev. Neurol. 19, 109–117. https://doi.org/10.1038/s41582-022-00763-1 (2023).
doi: 10.1038/s41582-022-00763-1
pubmed: 36693999
Steiner, T. J. et al. Migraine remains second among the world’s causes of disability, and first among young women: Findings from GBD2019. J. Headache Pain 21, 137. https://doi.org/10.1186/s10194-020-01208-0 (2020).
doi: 10.1186/s10194-020-01208-0
pubmed: 33267788
pmcid: 7708887
Stewart, W. F., Ricci, J. A., Chee, E., Morganstein, D. & Lipton, R. Lost productive time and cost due to common pain conditions in the US workforce. JAMA 290, 2443–2454. https://doi.org/10.1001/jama.290.18.2443 (2003).
doi: 10.1001/jama.290.18.2443
pubmed: 14612481
Robbins, M. S. Diagnosis and management of headache: A review. JAMA 325, 1874–1885. https://doi.org/10.1001/jama.2021.1640 (2021).
doi: 10.1001/jama.2021.1640
pubmed: 33974014
Buse, D. C. et al. Barriers to care in episodic and chronic migraine: Results from the chronic migraine epidemiology and outcomes study. Headache 61, 628–641. https://doi.org/10.1111/head.14103 (2021).
doi: 10.1111/head.14103
pubmed: 33797078
Zobdeh, F. et al. Pharmacological treatment of migraine: Drug classes, mechanisms of action, clinical trials and new treatments. Br. J. Pharmacol. 178, 4588–4607. https://doi.org/10.1111/bph.15657 (2021).
doi: 10.1111/bph.15657
pubmed: 34379793
Blake, P. & Burstein, R. Emerging evidence of occipital nerve compression in unremitting head and neck pain. J. Headache Pain 20, 76. https://doi.org/10.1186/s10194-019-1023-y (2019).
doi: 10.1186/s10194-019-1023-y
pubmed: 31266456
pmcid: 6734343
Guyuron, B., Varghai, A., Michelow, B. J., Thomas, T. & Davis, J. Corrugator supercilii muscle resection and migraine headaches. Plast. Reconstr. Surg. 106, 429–434. https://doi.org/10.1097/00006534-200008000-00030 (2000).
doi: 10.1097/00006534-200008000-00030
pubmed: 10946944
Perry, C. J. et al. Upregulation of inflammatory gene transcripts in periosteum of chronic migraineurs: Implications for extracranial origin of headache. Ann. Neurol. 79, 1000–1013. https://doi.org/10.1002/ana.24665 (2016).
doi: 10.1002/ana.24665
pubmed: 27091721
pmcid: 4884147
Mathew, P. G., Najib, U., Khaled, S. & Krel, R. Prevalence of occipital neuralgia at a community hospital-based headache clinic. Neurol. Clin. Pract. 11, 6–12. https://doi.org/10.1212/CPJ.0000000000000789 (2021).
doi: 10.1212/CPJ.0000000000000789
pubmed: 33968466
pmcid: 8101323
Abd-Elsayed, A., Nguyen, S. & Fiala, K. Radiofrequency ablation for treating headache. Curr. Pain Headache Rep. 23, 18. https://doi.org/10.1007/s11916-019-0755-3 (2019).
doi: 10.1007/s11916-019-0755-3
pubmed: 30830462
Evans, A. G. et al. Outcomes of transcutaneous nerve stimulation for migraine headaches: A systematic review and meta-analysis. J. Neurol. 269, 4021–4029. https://doi.org/10.1007/s00415-022-11059-1 (2022).
doi: 10.1007/s00415-022-11059-1
pubmed: 35296960
Evans, A. G. et al. Nerve blocks for occipital headaches: A systematic review and meta-analysis. J. Anaesthesiol. Clin. Pharmacol. 39, 170–180. https://doi.org/10.4103/joacp.JOACP_62_21 (2023).
doi: 10.4103/joacp.JOACP_62_21
pubmed: 37564833
pmcid: 10410037
Janis, J. E., Barker, J. C. & Palettas, M. Targeted peripheral nerve-directed onabotulinumtoxin a injection for effective long-term therapy for migraine headache. Plast. Reconstr. Surg. Glob. Open 5, e1270. https://doi.org/10.1097/GOX.0000000000001270 (2017).
doi: 10.1097/GOX.0000000000001270
pubmed: 28458982
pmcid: 5404453
Chang, I. A., Wells, M. W., Wang, G. M., Tatsuoka, C. & Guyuron, B. Nonpharmacologic treatments for chronic and episodic migraine: A systematic review and meta-analysis. Plast. Reconstr. Surg. 152, 1087–1098. https://doi.org/10.1097/PRS.0000000000010429 (2023).
doi: 10.1097/PRS.0000000000010429
pubmed: 36940145
Pang, X., Liu, C. & Peng, B. Anterior cervical surgery for the treatment of cervicogenic headache caused by cervical spondylosis. J. Pain. Res. 13, 2783–2789. https://doi.org/10.2147/JPR.S275680 (2020).
doi: 10.2147/JPR.S275680
pubmed: 33173327
pmcid: 7646456
Pikus, H. J. & Phillips, J. M. Characteristics of patients successfully treated for cervicogenic headache by surgical decompression of the second cervical root. Headache 35, 621–629. https://doi.org/10.1111/j.1526-4610.1995.hed3510621.x (1995).
doi: 10.1111/j.1526-4610.1995.hed3510621.x
pubmed: 8550364
Yang, L. et al. Anterior cervical decompression and fusion surgery for cervicogenic headache: A multicenter prospective cohort study. Front. Neurol. 13, 1064976. https://doi.org/10.3389/fneur.2022.1064976 (2022).
doi: 10.3389/fneur.2022.1064976
pubmed: 36504652
pmcid: 9731211
Jose, A., Nagori, S. A., Chattopadhyay, P. K. & Roychoudhury, A. Greater occipital nerve decompression for occipital neuralgia. J. Craniofac. Surg. 29, e518–e521. https://doi.org/10.1097/SCS.0000000000004549 (2018).
doi: 10.1097/SCS.0000000000004549
pubmed: 29762321
Pietramaggiori, G. & Scherer, S. Minimally invasive nerve- and muscle-sparing surgical decompression for occipital neuralgia. Plast. Reconstr. Surg. 151, 169–177. https://doi.org/10.1097/PRS.0000000000009777 (2023).
doi: 10.1097/PRS.0000000000009777
pubmed: 36251815
ElHawary, H., Barone, N., Baradaran, A. & Janis, J. E. Efficacy and safety of migraine surgery: a systematic review and meta-analysis of outcomes and complication rates. Ann. Surg. 275, e315–e323. https://doi.org/10.1097/SLA.0000000000005057 (2022).
doi: 10.1097/SLA.0000000000005057
pubmed: 35007230
Evans, A. G. et al. Outcomes of surgical treatment of migraines: a systematic review & meta-analysis. Plast. Surg. (Oakv) 31, 192–205. https://doi.org/10.1177/22925503211036701 (2023).
doi: 10.1177/22925503211036701
pubmed: 37188139
Guyuron, B., Kriegler, J. S., Davis, J. & Amini, S. B. Comprehensive surgical treatment of migraine headaches. Plast. Reconstr. Surg. 115, 1–9 (2005).
doi: 10.1097/01.PRS.0000145631.20901.84
pubmed: 15622223
Guyuron, B., Kriegler, J. S., Davis, J. & Amini, S. B. Five-year outcome of surgical treatment of migraine headaches. Plast. Reconstr. Surg. 127, 603–608. https://doi.org/10.1097/PRS.0b013e3181fed456 (2011).
doi: 10.1097/PRS.0b013e3181fed456
pubmed: 20966820
Guyuron, B. et al. A placebo-controlled surgical trial of the treatment of migraine headaches. Plast. Reconstr. Surg. 124, 461–468. https://doi.org/10.1097/PRS.0b013e3181adcf6a (2009).
doi: 10.1097/PRS.0b013e3181adcf6a
pubmed: 19644260
Janis, J. E. et al. A review of current evidence in the surgical treatment of migraine headaches. Plast. Reconstr. Surg. 134, 131S-141S. https://doi.org/10.1097/PRS.0000000000000661 (2014).
doi: 10.1097/PRS.0000000000000661
pubmed: 25254996
Ascha, M., Kurlander, D. E., Sattar, A., Gatherwright, J. & Guyuron, B. In-depth review of symptoms, triggers, and treatment of occipital migraine headaches (Site IV). Plast. Reconstr. Surg. 139, 1333e–1342e. https://doi.org/10.1097/PRS.0000000000003395 (2017).
doi: 10.1097/PRS.0000000000003395
pubmed: 28538577
Ducic, I., Hartmann, E. C. & Larson, E. E. Indications and outcomes for surgical treatment of patients with chronic migraine headaches caused by occipital neuralgia. Plast. Reconstr. Surg. 123, 1453–1461. https://doi.org/10.1097/PRS.0b013e3181a0720e (2009).
doi: 10.1097/PRS.0b013e3181a0720e
pubmed: 19407615
Gfrerer, L., Austen, W. G. Jr. & Janis, J. E. Migraine surgery. Plast. Reconstr. Surg. Glob. Open 7, e2291. https://doi.org/10.1097/GOX.0000000000002291 (2019).
doi: 10.1097/GOX.0000000000002291
pubmed: 31942333
pmcid: 6952133
Raposio, E. & Bertozzi, N. Trigger site inactivation for the surgical therapy of occipital migraine and tension-type headache: Our experience and review of the literature. Plast. Reconstr. Surg. Glob. Open 7, e2507. https://doi.org/10.1097/GOX.0000000000002507 (2019).
doi: 10.1097/GOX.0000000000002507
pubmed: 31942299
pmcid: 6908332
Bencardino, J. T. & Rosenberg, Z. S. Entrapment neuropathies of the shoulder and elbow in the athlete. Clin. Sports. Med. 25(465–487), vi–vii. https://doi.org/10.1016/j.csm.2006.03.005 (2006).
doi: 10.1016/j.csm.2006.03.005
pubmed: 16798135
Chirokikh, A. A. et al. Where does ultrasound fit in the diagnostic algorithm for cubital tunnel syndrome?. Hand (N Y) https://doi.org/10.1177/15589447231200645 (2023).
doi: 10.1177/15589447231200645
pubmed: 37746734
Du, R., Auguste, K. I., Chin, C. T., Engstrom, J. W. & Weinstein, P. R. Magnetic resonance neurography for the evaluation of peripheral nerve, brachial plexus, and nerve root disorders. J. Neurosurg. 112, 362–371. https://doi.org/10.3171/2009.7.JNS09414 (2010).
doi: 10.3171/2009.7.JNS09414
pubmed: 19663545
Graf, A., Ahmed, A. S., Roundy, R., Gottschalk, M. B. & Dempsey, A. Modern treatment of cubital tunnel syndrome: Evidence and controversy. J. Hand Surg. Glob. Online 5, 547–560. https://doi.org/10.1016/j.jhsg.2022.07.008 (2023).
doi: 10.1016/j.jhsg.2022.07.008
pubmed: 37521554
Petrover, D. & Richette, P. Treatment of carpal tunnel syndrome: From ultrasonography to ultrasound guided carpal tunnel release. Joint Bone Spine 85, 545–552. https://doi.org/10.1016/j.jbspin.2017.11.003 (2018).
doi: 10.1016/j.jbspin.2017.11.003
pubmed: 29154980
Vo, N. Q. et al. Magnetic resonance imaging as a first-choice imaging modality in carpal tunnel syndrome: New evidence. Acta Radiol. 64, 675–683. https://doi.org/10.1177/02841851221094227 (2023).
doi: 10.1177/02841851221094227
pubmed: 35437022
Robbins, N. M. et al. Magnetic resonance neurography in the diagnosis of neuropathies of the lumbosacral plexus: A pictorial review. Clin. Imaging 40, 1118–1130. https://doi.org/10.1016/j.clinimag.2016.07.003 (2016).
doi: 10.1016/j.clinimag.2016.07.003
pubmed: 27454861
Narouze, S. Occipital neuralgia diagnosis and treatment: The role of ultrasound. Headache 56, 801–807. https://doi.org/10.1111/head.12790 (2016).
doi: 10.1111/head.12790
pubmed: 26997206
Krakenes, J. et al. MRI assessment of the alar ligaments in the late stage of whiplash injury–a study of structural abnormalities and observer agreement. Neuroradiology 44, 617–624. https://doi.org/10.1007/s00234-002-0799-6 (2002).
doi: 10.1007/s00234-002-0799-6
pubmed: 12136365
Krakenes, J. & Kaale, B. R. Magnetic resonance imaging assessment of craniovertebral ligaments and membranes after whiplash trauma. Spine 31, 2820–2826. https://doi.org/10.1097/01.brs.0000245871.15696.1f (2006).
doi: 10.1097/01.brs.0000245871.15696.1f
pubmed: 17108836
Knackstedt, H., Krakenes, J., Bansevicius, D. & Russell, M. B. Magnetic resonance imaging of craniovertebral structures: Clinical significance in cervicogenic headaches. J. Headache Pain 13, 39–44. https://doi.org/10.1007/s10194-011-0387-4 (2012).
doi: 10.1007/s10194-011-0387-4
pubmed: 21947945
Chhabra, A. et al. MR neurography: Past, present, and future. AJR Am. J. Roentgenol. 197, 583–591. https://doi.org/10.2214/AJR.10.6012 (2011).
doi: 10.2214/AJR.10.6012
pubmed: 21862800
Diener, H. C. et al. Guidelines of the International Headache Society for controlled trials of preventive treatment of migraine attacks in episodic migraine in adults. Cephalalgia 40, 1026–1044. https://doi.org/10.1177/0333102420941839 (2020).
doi: 10.1177/0333102420941839
pubmed: 32722936
Chen, Y., Haacke, E. M. & Li, J. Peripheral nerve magnetic resonance imaging. F1000Res https://doi.org/10.12688/f1000research.19695.1 (2019).
doi: 10.12688/f1000research.19695.1
pubmed: 32201572
pmcid: 7076336
Janis, J. E. et al. The anatomy of the greater occipital nerve: Part II. Compression point topography. Plast. Reconstr. Surg. 126, 1563–1572. https://doi.org/10.1097/PRS.0b013e3181ef7f0c (2010).
doi: 10.1097/PRS.0b013e3181ef7f0c
pubmed: 20639804
Chung, M., Lu, K. B., Sanniec, K. & Amirlak, B. The greater occipital nerve and its dynamic compression points: Implications in migraine surgery. Plast. Reconstr. Surg. 149, 1321–1324. https://doi.org/10.1097/PRS.0000000000009094 (2022).
doi: 10.1097/PRS.0000000000009094
pubmed: 35383686
Saglam, L., Gayretli, O., Coskun, O. & Kale, A. Morphological features of the greater occipital nerve and its possible importance for interventional procedures. J. Anat. https://doi.org/10.1111/joa.13959 (2023).
doi: 10.1111/joa.13959
pubmed: 38041426
pmcid: 10780152
Griffith, J. F. & Guggenberger, R. Diagnostic Imaging IDKD. In Musculoskeletal Diseases 2021–2024 (eds Hodler, J. et al.) 259–268 (Springer, 2021).
doi: 10.1007/978-3-030-71281-5_18
Sneag, D. B. et al. MRI bullseye sign: An indicator of peripheral nerve constriction in parsonage-turner syndrome. Muscle Nerve 56, 99–106. https://doi.org/10.1002/mus.25480 (2017).
doi: 10.1002/mus.25480
pubmed: 27864992
Natsis, K. et al. The course of the greater occipital nerve in the suboccipital region: A proposal for setting landmarks for local anesthesia in patients with occipital neuralgia. Clin. Anat. 19, 332–336. https://doi.org/10.1002/ca.20190 (2006).
doi: 10.1002/ca.20190
pubmed: 16258972
Choi, I. & Jeon, S. R. Neuralgias of the head: Occipital neuralgia. J. Korean Med. Sci. 31, 479–488. https://doi.org/10.3346/jkms.2016.31.4.479 (2016).
doi: 10.3346/jkms.2016.31.4.479
pubmed: 27051229
pmcid: 4810328
American Association of Electrodiagnostic Medicine, A. A. o. N., American Academy of Physical, M. & Rehabilitation. Practice parameter for electrodiagnostic studies in carpal tunnel syndrome: summary statement. Muscle Nerve 25, 918–922 (2002). https://doi.org/10.1002/mus.10185
Hold, A. et al. 3-Tesla MRI-assisted detection of compression points in ulnar neuropathy at the elbow in correlation with intraoperative findings. J. Plast. Reconstr. Aesthet. Surg. 71, 1004–1009. https://doi.org/10.1016/j.bjps.2018.02.014 (2018).
doi: 10.1016/j.bjps.2018.02.014
pubmed: 29602661
Britz, G. W. et al. Carpal tunnel syndrome: Correlation of magnetic resonance imaging, clinical, electrodiagnostic, and intraoperative findings. Neurosurgery 37, 1097–1103. https://doi.org/10.1227/00006123-199512000-00009 (1995).
doi: 10.1227/00006123-199512000-00009
pubmed: 8584150