Plasma metabolomic profile of adiposity and body composition in childhood: The Genetics of Glucose regulation in Gestation and Growth cohort.
adiposity
body composition
childhood
metabolomics
Journal
Pediatric obesity
ISSN: 2047-6310
Titre abrégé: Pediatr Obes
Pays: England
ID NLM: 101572033
Informations de publication
Date de publication:
03 Jul 2024
03 Jul 2024
Historique:
revised:
21
05
2024
received:
20
12
2023
accepted:
07
06
2024
medline:
3
7
2024
pubmed:
3
7
2024
entrez:
3
7
2024
Statut:
aheadofprint
Résumé
This study identified metabolite modules associated with adiposity and body fat distribution in childhood using gold-standard measurements. We used cross-sectional data from 329 children at mid-childhood (age 5.3 ± 0.3 years; BMI 15.7 ± 1.5 kg/m We identified a 'green' module of 120 metabolites, primarily comprised of lipids (mostly sphingomyelins and phosphatidylcholine), that showed positive correlations (all FDR p < 0.05) with DXA estimates of total and truncal fat (ρ A module of metabolites was associated with adiposity measures in childhood.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e13149Subventions
Organisme : Canadian Institutes of Health Research (CIHR)
ID : MOP 115071
Organisme : Canadian Institutes of Health Research (CIHR)
ID : PJT-152989
Organisme : Fonds de recherche du Québec - Santé (FRQS)
ID : 20697
Organisme : Diabète Québec
Informations de copyright
© 2024 World Obesity Federation.
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