Clinical characteristics and management outcome of acute infectious endophthalmitis.
Humans
Endophthalmitis
/ diagnosis
Male
Female
Retrospective Studies
Middle Aged
Aged
Adult
Aged, 80 and over
Adolescent
Eye Infections, Bacterial
/ diagnosis
Young Adult
Acute Disease
Child
Child, Preschool
Visual Acuity
Infant
Anti-Bacterial Agents
/ therapeutic use
Vitreous Body
/ microbiology
Vitrectomy
/ methods
Endogenous endophthalmitis
Microbial analysis
Post-operative endophthalmitis
Post-traumatic endophthalmitis
Visual prognosis
Journal
International ophthalmology
ISSN: 1573-2630
Titre abrégé: Int Ophthalmol
Pays: Netherlands
ID NLM: 7904294
Informations de publication
Date de publication:
03 Jul 2024
03 Jul 2024
Historique:
received:
29
04
2024
accepted:
26
06
2024
medline:
3
7
2024
pubmed:
3
7
2024
entrez:
3
7
2024
Statut:
epublish
Résumé
This study aimed to investigate the demographics, clinical characteristics, and management outcomes of patients with acute infectious endophthalmitis (AIE). This retrospective chart review was conducted on all patients admitted with the clinical diagnosis of infectious endophthalmitis from 2017 to 2022. Demographic data, patients' clinical characteristics, the type of acute infectious endophthalmitis (post-operative, post-traumatic, bleb-associated, and endogenous endophthalmitis), the type of surgical procedure in the post-operative cases, the microbiologic analysis results of vitreous samples, therapeutic measures, and visual outcomes of patients were recorded. In this study, 182 participants, including 122 male (67%) and 60 (33%) female, were involved. The mean age of patients was 54.56 ± 21 years, with a range of 1-88 years old. The most prevalent type of AIE was post-operative (59.9%), followed by endogenous (19.2%), post-traumatic (17%), and bleb-associated (3.8%). The most common type of intraocular surgery in the post-operative subgroups of AIE patients was phacoemulsification (57.8%). The median (interquartile range) of the primary and final BCVA of patients was 1.5 (1.35, 1.85) and 0.65 (0.35, 1.35), respectively. Vitreous haziness grade (OR, 2.89; 95% CI, 1.11-5.74; p = 0.009) and the primary VA (OR, 60.34; 95% CI, 2.87-126.8; p = 0.008) revealed statistical significance for final vision loss. AIE is a devastating condition with poor visual outcomes, which presents with acute inflammatory signs and symptoms regardless of its type. However, prompt and appropriate treatment leads to visual recovery to a functional level in many patients.
Identifiants
pubmed: 38958789
doi: 10.1007/s10792-024-03239-x
pii: 10.1007/s10792-024-03239-x
doi:
Substances chimiques
Anti-Bacterial Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
308Informations de copyright
© 2024. The Author(s), under exclusive licence to Springer Nature B.V.
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