Fibroblast Activation Protein-Directed Imaging Outperforms

FAPI cancer imaging fibroblast activation protein mesothelioma thoracic cancer

Journal

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
ISSN: 1535-5667
Titre abrégé: J Nucl Med
Pays: United States
ID NLM: 0217410

Informations de publication

Date de publication:
03 Jul 2024
Historique:
received: 21 01 2024
accepted: 22 05 2024
medline: 4 7 2024
pubmed: 4 7 2024
entrez: 3 7 2024
Statut: aheadofprint

Résumé

The fibroblast activation protein (FAP) is highly expressed in tumor and stromal cells of mesothelioma and thus is an interesting imaging and therapeutic target. Previous data on PET imaging with radiolabeled FAP inhibitors (FAPIs) suggest high potential for superior tumor detection. Here, we report the data of a large malignant pleural mesothelioma cohort within a

Identifiants

DOI: 10.2967/jnumed.124.267473 PMID: 38960716
pubmed: 38960716
pii: jnumed.124.267473
doi: 10.2967/jnumed.124.267473
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024 by the Society of Nuclear Medicine and Molecular Imaging.

Auteurs

Lukas Kessler (L)

Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; lukas.kessler@uk-essen.de.
Institute of Diagnostic and Interventional Radiology and Neuroradiology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
German Cancer Consortium, Partner Site Essen, Essen, Germany.

Felix Schwaning (F)

Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
German Cancer Consortium, Partner Site Essen, Essen, Germany.

Martin Metzenmacher (M)

German Cancer Consortium, Partner Site Essen, Essen, Germany.
Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

Kim Pabst (K)

Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
German Cancer Consortium, Partner Site Essen, Essen, Germany.

Jens Siveke (J)

Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.
Division of Solid Tumor Translational Oncology, German Cancer Consortium, Partner Site Essen, Essen, Germany.
German Cancer Research Center, Heidelberg, Germany.

Marija Trajkovic-Arsic (M)

Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany.
Division of Solid Tumor Translational Oncology, German Cancer Consortium, Partner Site Essen, Essen, Germany.
German Cancer Research Center, Heidelberg, Germany.

Benedikt Schaarschmidt (B)

Institute of Diagnostic and Interventional Radiology and Neuroradiology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

Marcel Wiesweg (M)

German Cancer Consortium, Partner Site Essen, Essen, Germany.
Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

Clemens Aigner (C)

Department of Thoracic Surgery and Thoracic Endoscopy, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Department of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.

Till Plönes (T)

German Cancer Research Center, Heidelberg, Germany.
Department of Thoracic Surgery and Thoracic Endoscopy, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Division of Thoracic Surgery, Department of Visceral, Thoracic, and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
National Center for Tumor Diseases, Dresden, Germany; Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.

Kaid Darwiche (K)

Department of Pulmonary Medicine, Section of Interventional Pulmonology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

Servet Bölükbas (S)

Department of Thoracic Surgery and Thoracic Endoscopy, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

Martin Stuschke (M)

Department of Radiotherapy, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

Lale Umutlu (L)

Institute of Diagnostic and Interventional Radiology and Neuroradiology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

Michael Nader (M)

Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
German Cancer Consortium, Partner Site Essen, Essen, Germany.

Dirk Theegarten (D)

Institute of Pathology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; and.

Rainer Hamacher (R)

German Cancer Consortium, Partner Site Essen, Essen, Germany.
Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

Wilfried E E Eberhardt (WEE)

German Cancer Consortium, Partner Site Essen, Essen, Germany.
Division of Thoracic Oncology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

Martin Schuler (M)

German Cancer Consortium, Partner Site Essen, Essen, Germany.
Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

Ken Herrmann (K)

Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
German Cancer Consortium, Partner Site Essen, Essen, Germany.

Wolfgang P Fendler (WP)

Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
German Cancer Consortium, Partner Site Essen, Essen, Germany.

Hubertus Hautzel (H)

Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
German Cancer Consortium, Partner Site Essen, Essen, Germany.

Classifications MeSH