How D-amino acids embedded in the protein sequence modify its digestibility: Behaviour of digestive enzymes tested on a model peptide used as target.

Chymotrypsin In vitro digestion Pepsin Protein hydrolysis Racemization Trypsin

Journal

Food chemistry
ISSN: 1873-7072
Titre abrégé: Food Chem
Pays: England
ID NLM: 7702639

Informations de publication

Date de publication:
25 Jun 2024
Historique:
received: 26 09 2023
revised: 10 05 2024
accepted: 19 06 2024
medline: 5 7 2024
pubmed: 5 7 2024
entrez: 4 7 2024
Statut: aheadofprint

Résumé

D-amino acids can affect the action of digestive enzymes, hence the protein digestion. In this work the behaviour of the main stomach and gut digestive enzymes (pepsin, trypsin, and chymotrypsin) in the presence of D-amino acids in the protein chain was monitored over time using a model peptide, Ac-LDAQSAPLRVYVE-NH

Identifiants

pubmed: 38964099
pii: S0308-8146(24)01825-9
doi: 10.1016/j.foodchem.2024.140175
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

140175

Informations de copyright

Copyright © 2024. Published by Elsevier Ltd.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Nothing declared.

Auteurs

Francesca Accardo (F)

Department of Food and Drug, University of Parma, Parco Area delle Scienze, 27/A, 43124 Parma, Italy.

Barbara Prandi (B)

Department of Food and Drug, University of Parma, Parco Area delle Scienze, 27/A, 43124 Parma, Italy.

Luca Dellafiora (L)

Department of Food and Drug, University of Parma, Parco Area delle Scienze, 27/A, 43124 Parma, Italy.

Tullia Tedeschi (T)

Department of Food and Drug, University of Parma, Parco Area delle Scienze, 27/A, 43124 Parma, Italy. Electronic address: tullia.tedeschi@unipr.it.

Stefano Sforza (S)

Department of Food and Drug, University of Parma, Parco Area delle Scienze, 27/A, 43124 Parma, Italy.

Classifications MeSH