Phenotyping variability in early socio-communicative skills in young children with autism and its influence on later development.
autism spectrum disorders
cluster analysis
deep phenotyping
joint attention
nonverbal communication
phenotype
trajectories
Journal
Autism research : official journal of the International Society for Autism Research
ISSN: 1939-3806
Titre abrégé: Autism Res
Pays: United States
ID NLM: 101461858
Informations de publication
Date de publication:
04 Jul 2024
04 Jul 2024
Historique:
received:
22
12
2023
accepted:
12
06
2024
medline:
5
7
2024
pubmed:
5
7
2024
entrez:
5
7
2024
Statut:
aheadofprint
Résumé
Children with autism spectrum disorder (ASD) often face challenges in early social communication skills, prompting the need for a detailed exploration of specific behaviors and their impact on cognitive and adaptive functioning. This study aims to address this gap by examining the developmental trajectories of early social communication skills in preschoolers with ASD aged 18-60 months, comparing them to age-matched typically developing (TD) children. Utilizing the early social communication scales (ESCS), the research employs a longitudinal design to capture changes over time. We apply a principal component analysis (PCA) to ESCS variables to identify underlying components, and cluster analysis to identify subgroups based on preverbal communication profiles. The results reveal consistent differences in early social communication skills between ASD and TD children, with ASD children exhibiting reduced skills. PCA identifies two components, distinguishing objects-directed behaviors and social interaction-directed behaviors. Cluster analysis identifies three subgroups of autistic children, each displaying specific communication profiles associated with distinct cognitive and adaptive functioning trajectories. In conclusion, this study provides a nuanced understanding of early social communication development in ASD, emphasizing the importance of low-level behaviors. The identification of subgroups and their unique trajectories contributes to a more comprehensive understanding of ASD heterogeneity. These findings underscore the significance of early diagnosis, focusing on specific behaviors predicting cognitive and adaptive functioning outcomes. The study encourages further research to explore the sequential development of these skills, offering valuable insights for interventions and support strategies.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Swiss National Center of Competence for Research (NCCR) Synapsy
ID : 51NF40-185897
Organisme : Swiss National Science Foundation
ID : 163859
Pays : Switzerland
Organisme : Swiss National Science Foundation
ID : 190084
Pays : Switzerland
Organisme : Swiss National Science Foundation
ID : 202235
Pays : Switzerland
Organisme : Swiss National Science Foundation
ID : 212653
Pays : Switzerland
Organisme : Fondation Privée des Hôpitaux Universitaires de Genève
Organisme : Fondation Pôle Autisme
Informations de copyright
© 2024 The Author(s). Autism Research published by International Society for Autism Research and Wiley Periodicals LLC.
Références
Adamson, L. B., Bakeman, R., Suma, K., & Robins, D. L. (2019). An expanded view of joint attention: Skill, engagement, and language in typical development and autism. Child Development, 90, e1–e18.
American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders: DSM‐5. American Psychiatric Association.
Bakeman, R., & Adamson, L. B. (1984). Coordinating attention to people and objects in mother‐infant and peer‐infant interaction. Child Development, 55, 1278.
Bates, E., Camaioni, L., & Volterra, V. (1975). The acquisition of performatives prior to speech. Merrill‐Palmer Quarterly, 21, 205–226.
Bottema‐Beutel, K. (2016). Associations between joint attention and language in autism spectrum disorder and typical development: A systematic review and meta‐regression analysis: Associations between joint attention. Autism Research, 9, 1021–1035.
Brooks, R., & Meltzoff, A. N. (2008). Infant gaze following and pointing predict accelerated vocabulary growth through two years of age: A longitudinal, growth curve modeling study. Journal of Child Language, 35, 207–220.
Bruinsma, Y., Koegel, R. L., & Koegel, L. K. (2004). Joint attention and children with autism: A review of the literature. Mental Retardation and Developmental Disabilities Research Reviews, 10, 169–175.
Cassel, T. D., Messinger, D. S., Ibanez, L. V., Haltigan, J. D., Acosta, S. I., & Buchman, A. C. (2007). Early social and emotional communication in the infant siblings of children with autism spectrum disorders: An examination of the broad phenotype. Journal of Autism and Developmental Disorders, 37, 122–132.
Charman, T. (2003). Why is joint attention a pivotal skill in autism? Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 358, 315–324.
Chiang, C.‐H., Soong, W.‐T., Lin, T.‐L., & Rogers, S. J. (2008). Nonverbal communication skills in young children with autism. Journal of Autism and Developmental Disorders, 38, 1898–1906.
Dawson, G., Toth, K., Abbott, R., Osterling, J., Munson, J., Estes, A., & Liaw, J. (2004). Early social attention impairments in autism: Social orienting, joint attention, and attention to distress. Developmental Psychology, 40, 271–283.
Field, A. (2009). Discovering statistics using SPSS. SAGE Publications.
Franchini, M., Armstrong, V. L., Schaer, M., & Smith, I. M. (2019). Initiation of joint attention and related visual attention processes in infants with autism spectrum disorder: Literature review. Child Neuropsychology, 25, 287–317.
Franchini, M., Hamodat, T., Armstrong, V. L., Sacrey, L. A. R., Brian, J., Bryson, S. E., Garon, N., Roberts, W., Zwaigenbaum, L., & Smith, I. M. (2019). Infants at risk for autism spectrum disorder: Frequency, quality, and variety of joint attention behaviors. Journal of Abnormal Child Psychology, 47, 907–920.
Franchini, M., Zöller, D., Gentaz, E., Glaser, B., Wood de Wilde, H., Kojovic, N., Eliez, S., & Schaer, M. (2018). Early adaptive functioning trajectories in preschoolers with autism spectrum disorders. Journal of Pediatric Psychology, 43, 800–813.
Goldin‐Meadow, S. (2014). Widening the lens: What the manual modality reveals about language, learning and cognition. Philosophical Transactions of the Royal Society B, Biological Sciences, 369, 20130295.
Gotham, K., Pickles, A., & Lord, C. (2009). Standardizing ADOS scores for a measure of severity in autism spectrum disorders. Journal of Autism and Developmental Disorders, 39, 693–705.
Heymann, P., Northrup, J. B., West, K. L., Parladé, M. V., Leezenbaum, N. B., & Iverson, J. M. (2018). Coordination is key: Joint attention and vocalisation in infant siblings of children with autism spectrum disorder: Joint attention and vocalisation in ASD. International Journal of Language & Communication Disorders, 53, 1007–1020.
Hirsh‐Pasek, K., Adamson, L. B., Bakeman, R., Owen, M. T., Golinkoff, R. M., Pace, A., Yust, P. K. S., & Suma, K. (2015). The contribution of early communication quality to low‐income children's language success. Psychological Science, 26, 1071–1083.
Kasari, C., Gulsrud, A., Freeman, S., Paparella, T., & Hellemann, G. (2012). Longitudinal follow‐up of children with autism receiving targeted interventions on joint attention and play. Journal of the American Academy of Child and Adolescent Psychiatry, 51, 487–495.
Kasari, C., Paparella, T., Freeman, S., & Jahromi, L. B. (2008). Language outcome in autism: Randomized comparison of joint attention and play interventions. Journal of Consulting and Clinical Psychology, 76, 125–137.
Kodinariya, T. M., & Makwana, P. R. (2013). Review on determining number of cluster in K‐means clustering. International Journal, 1, 90–95.
Latrèche, K., Kojovic, N., Franchini, M., & Schaer, M. (2021). Attention to face as a predictor of developmental change and treatment outcome in young children with autism spectrum disorder. Biomedicine, 9, 942.
Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Jr., Leventhal, B. L., DiLavore, P. C., Pickles, A., & Rutter, M. (2000). The autism diagnostic observation schedule–generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30, 393–398.
Lord, C., Rutter, M., DiLavore, P., Risi, S., Gotham, K., & Bishop, S. (2012). Autism diagnostic observation schedule‐2nd edition (ADOS‐2) (p. 284). Western Psychological Corporation.
Luyster, R., & Lord, C. (2009). Word learning in children with autism spectrum disorders. Developmental Psychology, 45, 1774–1786.
Mancini, V., Sandini, C., Padula, M. C., Zöller, D., Schneider, M., Schaer, M., & Eliez, S. (2020). Positive psychotic symptoms are associated with divergent developmental trajectories of hippocampal volume during late adolescence in patients with 22q11DS. Molecular Psychiatry, 25, 2844–2859.
Manzi, F., Savarese, G., Mollo, M., & Iannaccone, A. (2020). Objects as communicative mediators in children with autism spectrum disorder. Frontiers in Psychology, 11, 1269.
Moore, C., & D'Entremont, B. (2001). Developmental changes in pointing as a function of attentional focus. Journal of Cognition and Development, 2(2), 109–129. https://doi.org/10.1207/S15327647JCD0202_1
Mullen, E. M. (1995). Mullen scales of early learning (pp. 58–64). American Guidance Service.
Mundy, P. (1995). Joint attention and social‐emotional approach behavior in children with autism. Development and Psychopathology, 7, 63–82.
Mundy, P., Block, J., Delgado, C., Pomares, Y., van Hecke, A. V., & Parlade, M. V. (2007). Individual differences and the development of joint attention in infancy. Child Development, 78, 938–954.
Mundy, P., Delgado, C., Block, J., Venezia, M., Hogan, A., & Seibert, J. (2003). Early social communication scales (ESCS). University of Miami.
Mundy, P., & Newell, L. (2007). Attention, joint attention, and social cognition. Current Directions in Psychological Science, 16, 269–274.
Mundy, P., Sigman, M., & Kasari, C. (1990). A longitudinal study of joint attention and language development in autistic children. Journal of Autism and Developmental Disorders, 20, 115–128.
Mundy, P., Sigman, M., & Kasari, C. (1994). Joint attention, developmental level, and symptom presentation in autism. Development and Psychopathology, 6, 389–401.
Mundy, P., Sigman, M., Kasari, C., & Yirmiya, N. (1988). Nonverbal communication skills in down syndrome children. Child Development, 59, 235.
Mundy, P., Sullivan, L., & Mastergeorge, A. M. (2009). A parallel and distributed‐processing model of joint attention, social cognition and autism. Autism Research, 2, 2–21.
Mutlu, A. K., Schneider, M., Debbané, M., Badoud, D., Eliez, S., & Schaer, M. (2013). Sex differences in thickness, and folding developments throughout the cortex. NeuroImage, 82, 200–207.
Paparella, T., Goods, K. S., Freeman, S., & Kasari, C. (2011). The emergence of nonverbal joint attention and requesting skills in young children with autism. Journal of Communication Disorders, 44, 569–583.
Peng, H., & Lu, Y. (2012). Model selection in linear mixed effect models. Journal of Multivariate Analysis, 109, 109–129.
Piaget, J. (1960). The general problems of the psychobiological development of the child. In J. Tanner & B. Inhelder (Eds.), Discussions on child development. Tavistock.
Piaget, J. (2013). The construction of reality in the child (Vol. 82). Routledge.
Piaget, J., & Cook, M. (1952). The origins of intelligence in children (Vol. 8). International Universities Press.
Robinson, P. N. (2012). Deep phenotyping for precision medicine. Human Mutation, 33, 777–780.
Rogers, S. J., & Dawson, G. (2010). Early start Denver model for young children with autism: Promoting language, learning, and engagement. The Guilford Press.
Rozga, A., Hutman, T., Young, G. S., Rogers, S. J., Ozonoff, S., Dapretto, M., & Sigman, M. (2011). Behavioral profiles of affected and unaffected siblings of children with autism: Contribution of measures of mother–infant interaction and nonverbal communication. Journal of Autism and Developmental Disorders, 41, 287–301.
Schaeffer, J., Abd el‐Raziq, M., Castroviejo, E., Durrleman, S., Ferré, S., Grama, I., Hendriks, P., Kissine, M., Manenti, M., Marinis, T., Meir, N., Novogrodsky, R., Perovic, A., Panzeri, F., Silleresi, S., Sukenik, N., Vicente, A., Zebib, R., Prévost, P., & Tuller, L. (2023). Language in autism: Domains, profiles and co‐occurring conditions. Journal of Neural Transmission, 130, 433–457.
Schietecatte, I., Roeyers, H., & Warreyn, P. (2012). Exploring the nature of joint attention impairments in young children with autism spectrum disorder: Associated social and cognitive skills. Journal of Autism and Developmental Disorders, 42, 1–12.
Schneider, M., Schaer, M., Mutlu, A. K., Menghetti, S., Glaser, B., Debbané, M., & Eliez, S. (2014). Clinical and cognitive risk factors for psychotic symptoms in 22q11.2 deletion syndrome: A transversal and longitudinal approach. European Child & Adolescent Psychiatry, 23, 425–436.
Seibert, J. M., Hogan, A. E., & Mundy, P. C. (1982). Assessing interactional competencies: The early social‐communication scales. Infant Mental Health Journal, 3, 244–258.
Sparrow, S., Cicchetti, D., & Balla, D. (2005). Vineland adaptive behavior scales–second edition. AGS Publications.
Stevens, J. P. (2001). Applied multivariate statistics for the social sciences (4th ed.). L. Erlbaum Associates.
Thissen, D., Steinberg, L., & Kuang, D. (2002). Quick and easy implementation of the Benjamini‐Hochberg procedure for controlling the false positive rate in multiple comparisons. Journal of Educational and Behavioral Statistics, 27, 77–83.
Tomasello, M. (2009). Constructing a language. Harvard University Press.
Tomasello, M., & Carpenter, M. (2007). Shared intentionality. Developmental Science, 10, 121–125.
Tomasello, M., Carpenter, M., & Liszkowski, U. (2007). A new look at infant pointing. Child Development, 78, 705–722.
Toth, K., Munson, J. N., Meltzoff, A., & Dawson, G. (2006). Early predictors of communication development in young children with autism spectrum disorder: Joint attention, imitation, and toy play. Journal of Autism and Developmental Disorders, 36, 993–1005.
Trueswell, J. C., Lin, Y., Armstrong, B., III, Cartmill, E. A., Goldin‐Meadow, S., & Gleitman, L. R. (2016). Perceiving referential intent: Dynamics of reference in natural parent–child interactions. Cognition, 148, 117–135.
Werner, H., & Kaplan, B. (1963). Symbol formation. Wiley.
Wetherby, A. M., Woods, J., Allen, L., Cleary, J., Dickinson, H., & Lord, C. (2004). Early indicators of autism spectrum disorders in the second year of life. Journal of Autism and Developmental Disorders, 34, 473–493.
Wimpory, D. C., Hobson, R. P., Williams, J. M. G., & Nash, S. (2000). Are infants with autism socially engaged? A study of recent retrospective parental reports. Journal of Autism and Developmental Disorders, 30, 525–536.