Cadmium nanocluster as a safe nanocarrier: biodistribution in BALB/c mice and application to carry crocin to breast cancer cell lines.

CD44 Cadmium nanocluster antioxidant enzymes breast cancer cell line hyaluronic acid oxidative stress

Journal

Exploration of targeted anti-tumor therapy
ISSN: 2692-3114
Titre abrégé: Explor Target Antitumor Ther
Pays: United States
ID NLM: 101770662

Informations de publication

Date de publication:
2024
Historique:
received: 12 09 2023
accepted: 27 12 2023
medline: 5 7 2024
pubmed: 5 7 2024
entrez: 5 7 2024
Statut: ppublish

Résumé

Metal nanoclusters are emerging nanomaterials applicable for drug delivery. Here, the toxicity and oxidative stress induction of divalent cationic cadmium (Cd Using a green chemistry route, a Cd nanocluster (Cd-NC) was synthesized based on bovine serum albumin. After characterization, its genotoxicity and oxidative stress induction were studied in both The comet assay results indicated that, unlike Cd The Cd-NC was completely safe and is a promising candidate for delivering anticancer drugs/phytochemicals into the targeted breast tumors.

Identifiants

pubmed: 38966182
doi: 10.37349/etat.2024.00233
pmc: PMC11220307
doi:

Types de publication

Journal Article

Langues

eng

Pagination

522-542

Informations de copyright

© The Author(s) 2024.

Déclaration de conflit d'intérêts

The authors declare that they have no conflicts of interest.

Auteurs

Moslem Jafarisani (M)

Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University (TMU), Tehran 14155-331, Iran.

S Ali Hashemi (SA)

Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University (TMU), Tehran 14155-331, Iran.

Nassim Faridi (N)

Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University (TMU), Tehran 14155-331, Iran.

Mir F Mousavi (MF)

Institute for Natural Products and Medicinal Plants (INPMP), Tarbiat Modares University (TMU), Tehran 14155-331, Iran.
Department of Chemistry, Faculty of basic Sciences, Tarbiat Modares University (TMU), Tehran 14115-175, Iran.

S Zahra Bathaie (SZ)

Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University (TMU), Tehran 14155-331, Iran.
Institute for Natural Products and Medicinal Plants (INPMP), Tarbiat Modares University (TMU), Tehran 14155-331, Iran.

Classifications MeSH