Vertical Parasagittal Hemispherotomy in a Pediatric Case of Epilepsy Due to Rasmussen Encephalitis: 2-Dimensional Operative Video.


Journal

Operative neurosurgery (Hagerstown, Md.)
ISSN: 2332-4260
Titre abrégé: Oper Neurosurg (Hagerstown)
Pays: United States
ID NLM: 101635417

Informations de publication

Date de publication:
05 Jul 2024
Historique:
received: 15 03 2024
accepted: 11 05 2024
medline: 5 7 2024
pubmed: 5 7 2024
entrez: 5 7 2024
Statut: aheadofprint

Résumé

Hemispherotomy is an effective disconnection technique for the treatment of different forms of drug-resistant epilepsy due to encephalopathies with unilateral hemispheric involvement.1-8 We describe the case of a 6-year-old child affected by Rasmussen encephalitis who underwent right vertical parasagittal hemispherotomy.9 The goal of the procedure was to isolate the basal ganglia region by interrupting the interhemispheric and intrahemispheric white matter connectivity. The main surgical steps include the transcortical approach to the lateral ventricle, the posterior callosotomy, the fimbria-fornix incision, the laterothalamic vertical incision, the anterior callosotomy, the frontobasal disconnection, and the transcaudate lateral incision to the anterior temporal horn.7,10 At 10-month follow-up, the patient was seizure free with a stable left hemiparesis. The antiepileptic therapy was progressively interrupted. The video describes the main surgical steps, using both intraoperative videos and advanced three-dimensional modeling of neuroimaging pictures. Patient' parents consented to the procedure. The participants and any identifiable individuals consented to publication of his/her image. Approval from the ethics committee was acquired.

Identifiants

pubmed: 38967453
doi: 10.1227/ons.0000000000001261
pii: 01787389-990000000-01224
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Ministero della Salute
ID : n.a.
Organisme : Ministero dell’Istruzione, dell’Universitàe della Ricerca
ID : 1553 11.10.2022

Informations de copyright

Copyright © Congress of Neurological Surgeons 2024. All rights reserved.

Références

de Palma L, Pietrafusa N, Gozzo F, et al. Outcome after hemispherotomy in patients with intractable epilepsy: comparison of techniques in the Italian experience. Epilepsy Behav. 2019;93:22-28.
Cossu M, Nichelatti M, De Benedictis A, et al. Lateral versus vertical hemispheric disconnection for epilepsy: a systematic review and meta-analysis. J Neurosurg. 2022;136(6):1627-1637.
Marras CE, Granata T, Franzini A, et al. Hemispherotomy and functional hemispherectomy: indications and outcome. Epilepsy Res. 2010;89(1):104-112.
Villemure JG, Mascott CR. Peri-insular hemispherotomy: surgical principles and anatomy. Neurosurgery. 1995;37(5):975-981.
Schramm J, Kral T, Clusmann H. Transsylvian keyhole functional hemispherectomy. Neurosurgery. 2001;49(4):891-901.
Danielpour M, Von Koch CS, Ojemann SG, Peacock WJ. Disconnective hemispherectomy. Pediatr Neurosurg. 2001;35(4):169-172.
Delalande O, Bulteau C, Dellatolas G, et al. Vertical parasagittal hemispherotomy: surgical procedures and clinical long-term outcomes in a population of 83 children. Neurosurgery. 2007;60(2 Suppl 1):ONS19-ONS32.
Giordano F, Spacca B, Barba C, et al. Vertical extraventricular functional hemispherotomy: a new variant for hemispheric disconnection. Technical notes and results in three patients. Childs Nerv Syst. 2015;31(11):2151-2160.
Bien CG, Granata T, Antozzi C, et al. Pathogenesis, diagnosis and treatment of Rasmussen encephalitis: a European consensus statement. Brain. 2005;128(Pt 3):454-471.
De Benedictis A, Marasi A, Rossi-Espagnet MC, et al. Vertical hemispherotomy: contribution of advanced three-dimensional modeling for presurgical planning and training. J Clin Med. 2023;12(11):3779.

Auteurs

Alessandro De Benedictis (A)

Neurosurgery Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Chiara Pepi (C)

Epilepsy and Movement Disorders Unit, Bambino Gesù Children's Hospital, IRCCS, European Reference Network EpiCARE, Rome, Italy.

Aalap Herur-Raman (A)

George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA.

Matteo Barba (M)

Neurosurgery Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Alessandra Marasi (A)

Functional and Interventional Neuroradiology Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Maria Camilla Rossi-Espagnet (MC)

Neuroradiology Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Antonio Napolitano (A)

Medical Physics Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Sabrina Rossi (S)

Pathology Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Davide Luglietto (D)

Neurosurgery Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Department of Electrical Engineering and Information Technology (DIETI), Federico II University, Naples, Italy.

Sergio Capelli (S)

Division of Neurosurgery, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
Division of Neurosurgery, Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.

Caterina Zanus (C)

Institute for Maternal and Child Health - IRCCS "Burlo Garofolo", Trieste, Italy.

Alessandra Savioli (A)

Intensive Care Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Luca de Palma (L)

Epilepsy and Movement Disorders Unit, Bambino Gesù Children's Hospital, IRCCS, European Reference Network EpiCARE, Rome, Italy.

Nicola Specchio (N)

Epilepsy and Movement Disorders Unit, Bambino Gesù Children's Hospital, IRCCS, European Reference Network EpiCARE, Rome, Italy.

Carlo Efisio Marras (CE)

Neurosurgery Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Classifications MeSH