Equidae pythiosis in Brazil and the world: a systematic review of the last 63 years (1960-2023).
Pythium Insidiosum
Clinical feature
Diagnosis
Epidemiology
Horse
Infectious disease
Oomycota
Therapy
Journal
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]
ISSN: 1678-4405
Titre abrégé: Braz J Microbiol
Pays: Brazil
ID NLM: 101095924
Informations de publication
Date de publication:
05 Jul 2024
05 Jul 2024
Historique:
received:
07
03
2024
accepted:
24
06
2024
medline:
5
7
2024
pubmed:
5
7
2024
entrez:
5
7
2024
Statut:
aheadofprint
Résumé
This systematic review compiles reports of clinical pythiosis in horses, mules and donkeys from 1960 to 2023 worldwide, focusing on Brazil. We searched databases and included 71 articles detailing clinical characteristics, geographic distribution, epidemiology, diagnostic methods, therapies, and outcomes. The results showed that publications on equine pythiosis have significantly increased since 2010. Brazil reported the highest incidence, comprising 55% of cases, predominantly in the southern, northeastern, and central-western regions during summer and autumn. Cutaneous pythiosis was the most prevalent form, generally presenting as single lesions in the appendicular region, and affected females more than males. Diagnosis typically involved histopathology, used alone or with other methods. Various treatments have been employed, with surgery, often combined with chemotherapy and immunotherapy, being the most common. Notably, 80.84% of treated animals recovered, highlighting the effectiveness of these therapies in enhancing survival rates. The limitations of the study included the lack of data in published case reports, which made it difficult to collect and calculate epidemiological data. Additionally, we recognize that pythiosis in Brazil is underreported, since this disease does not have mandatory notification and several cases are not registered and/or reported in the literature. Lastly, it is hypothesized that equid pythiosis may be more widespread than currently known, and its real occurrence in Brazil remains uncertain.
Identifiants
pubmed: 38967702
doi: 10.1007/s42770-024-01435-6
pii: 10.1007/s42770-024-01435-6
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
ID : Financial code 001
Organisme : Conselho Nacional de Desenvolvimento Científico e Tecnológico
ID : Conselho Nacional de Desenvolvimento Científico e Tecnológico
Organisme : Conselho Nacional de Desenvolvimento Científico e Tecnológico
ID : Conselho Nacional de Desenvolvimento Científico e Tecnológico
Organisme : Conselho Nacional de Desenvolvimento Científico e Tecnológico
ID : Conselho Nacional de Desenvolvimento Científico e Tecnológico
Informations de copyright
© 2024. The Author(s) under exclusive licence to Sociedade Brasileira de Microbiologia.
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