Maternal use of snus as smokeless tobacco in pregnancy and infant lung function.


Journal

ERJ open research
ISSN: 2312-0541
Titre abrégé: ERJ Open Res
Pays: England
ID NLM: 101671641

Informations de publication

Date de publication:
Jul 2024
Historique:
received: 01 12 2023
accepted: 09 03 2024
medline: 9 7 2024
pubmed: 9 7 2024
entrez: 9 7 2024
Statut: epublish

Résumé

Smoking in pregnancy has detrimental effects on infant respiratory health, while the effects of other nicotine-containing products on infant lung function are unclear. We aimed to explore if smokeless tobacco such as snus used in pregnancy increased the risk of lower lung function in infancy and if the associations differed by sex. From the Scandinavian population-based Preventing Atopic Dermatitis and ALLergies in Children birth cohort, we included 1163 infants with available tidal flow-volume measurements at 3 months of age and maternal self-reported use of nicotine-containing products in pregnancy. The risk of a ratio of time to peak tidal expiratory flow to total expiratory time <25th percentile by any nicotine exposure, snus exclusively and cigarette smoking with or without other nicotine-containing products was explored by regression analyses adjusting for maternal age, education and asthma. Overall 120 out of 1163 (10.3%) infants were exposed to any nicotine Our study suggests that

Sections du résumé

Background UNASSIGNED
Smoking in pregnancy has detrimental effects on infant respiratory health, while the effects of other nicotine-containing products on infant lung function are unclear. We aimed to explore if smokeless tobacco such as snus used in pregnancy increased the risk of lower lung function in infancy and if the associations differed by sex.
Methods UNASSIGNED
From the Scandinavian population-based Preventing Atopic Dermatitis and ALLergies in Children birth cohort, we included 1163 infants with available tidal flow-volume measurements at 3 months of age and maternal self-reported use of nicotine-containing products in pregnancy. The risk of a ratio of time to peak tidal expiratory flow to total expiratory time <25th percentile by any nicotine exposure, snus exclusively and cigarette smoking with or without other nicotine-containing products was explored by regression analyses adjusting for maternal age, education and asthma.
Results UNASSIGNED
Overall 120 out of 1163 (10.3%) infants were exposed to any nicotine
Conclusion UNASSIGNED
Our study suggests that

Identifiants

pubmed: 38978555
doi: 10.1183/23120541.00958-2023
pii: 00958-2023
pmc: PMC11228604
pii:
doi:

Types de publication

Journal Article

Langues

eng

Informations de copyright

Copyright ©The authors 2024.

Déclaration de conflit d'intérêts

Conflict of interest: K.E.S. Bains reports support for the present manuscript from The PreventADALL study was supported by sponsors to the institutions listed in the financial disclosures outlined in the manuscript. Salary for the PhD project of K.E.S. Bains was provided by Xtrastiftelsen and Klosterstiftelsen. Conflict of interest: E.M. Rehbinder reports receiving personal fees from honoraria for lectures from Sanofi Genzyme, Leo Pharma, NAAF, PEF and Abbvie, outside the submitted work. Conflict of interest: The remaining authors have nothing to disclose.

Auteurs

Karen Eline Stensby Bains (KES)

Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway.
University of Oslo, Faculty of Medicine, Institute of Clinical Medicine, Oslo, Norway.

Ina Kreyberg (I)

Department of Dermatology and Venerology, Oslo University Hospital, Oslo, Norway.
Shared second authorship.

Martin Färdig (M)

Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.
Department of Women's and Children's Health, Karolinska Institute, Stockholm, Sweden.
Shared second authorship.

Berit Granum (B)

Department of Environmental Health, Norwegian Institute of Public Health, Oslo, Norway.

Hrefna K Gudmundsdóttir (HK)

Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway.
University of Oslo, Faculty of Medicine, Institute of Clinical Medicine, Oslo, Norway.

Guttorm Haugen (G)

University of Oslo, Faculty of Medicine, Institute of Clinical Medicine, Oslo, Norway.
Division of Obstetrics and Gynaecology, Oslo University Hospital, Oslo, Norway.

Gunilla Hedlin (G)

Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.
Department of Women's and Children's Health, Karolinska Institute, Stockholm, Sweden.

Katarina Hilde (K)

University of Oslo, Faculty of Medicine, Institute of Clinical Medicine, Oslo, Norway.
Division of Obstetrics and Gynaecology, Oslo University Hospital, Oslo, Norway.

Christine Monceyron Jonassen (CM)

Department of Virology, Norwegian Institute of Public Health, Oslo, Norway.
Center for Laboratory Medicine, Østfold Hospital Trust, Grålum, Norway.

Björn Nordlund (B)

Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.
Department of Women's and Children's Health, Karolinska Institute, Stockholm, Sweden.

Eva M Rehbinder (EM)

University of Oslo, Faculty of Medicine, Institute of Clinical Medicine, Oslo, Norway.
Department of Dermatology and Venerology, Oslo University Hospital, Oslo, Norway.

Corina Silvia Rueegg (CS)

Oslo Centre for Biostatistics and Epidemiology, Oslo University Hospital, Oslo, Norway.

Håvard O Skjerven (HO)

Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway.
University of Oslo, Faculty of Medicine, Institute of Clinical Medicine, Oslo, Norway.

Anne Cathrine Staff (AC)

University of Oslo, Faculty of Medicine, Institute of Clinical Medicine, Oslo, Norway.
Division of Obstetrics and Gynaecology, Oslo University Hospital, Oslo, Norway.

Cilla Söderhäll (C)

Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.
Department of Women's and Children's Health, Karolinska Institute, Stockholm, Sweden.

Riyas Vettukattil (R)

Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway.
University of Oslo, Faculty of Medicine, Institute of Clinical Medicine, Oslo, Norway.

Karin C Lødrup Carlsen (KCL)

Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway.
University of Oslo, Faculty of Medicine, Institute of Clinical Medicine, Oslo, Norway.

Classifications MeSH