Air pollution exposure during pregnancy and lung function in childhood: The LUIS study.
air pollution
fetus
lung
nitrogen dioxide
particulate matter
Journal
Pediatric pulmonology
ISSN: 1099-0496
Titre abrégé: Pediatr Pulmonol
Pays: United States
ID NLM: 8510590
Informations de publication
Date de publication:
09 Jul 2024
09 Jul 2024
Historique:
revised:
13
05
2024
received:
26
02
2024
accepted:
27
06
2024
medline:
9
7
2024
pubmed:
9
7
2024
entrez:
9
7
2024
Statut:
aheadofprint
Résumé
The adverse effects of high air pollution levels on childhood lung function are well-known. Limited evidence exists on the effects of moderate exposure levels during early life on childhood lung function. We investigated the association of exposure to moderate air pollution during pregnancy, infancy, and preschool time with lung function at school age in a Swiss population-based study. Fine-scale spatiotemporal model estimates of particulate matter with a diameter <2.5 µm (PM We included 2182 children, ages 6-17 years. Prenatal air pollution exposure was associated with reduced lung function at school age. In children aged 12 years, per 10 µg·m In utero lung development is most sensitive to air pollution exposure, since even modest PM
Sections du résumé
BACKGROUND
BACKGROUND
The adverse effects of high air pollution levels on childhood lung function are well-known. Limited evidence exists on the effects of moderate exposure levels during early life on childhood lung function. We investigated the association of exposure to moderate air pollution during pregnancy, infancy, and preschool time with lung function at school age in a Swiss population-based study.
METHODS
METHODS
Fine-scale spatiotemporal model estimates of particulate matter with a diameter <2.5 µm (PM
RESULTS
RESULTS
We included 2182 children, ages 6-17 years. Prenatal air pollution exposure was associated with reduced lung function at school age. In children aged 12 years, per 10 µg·m
CONCLUSION
CONCLUSIONS
In utero lung development is most sensitive to air pollution exposure, since even modest PM
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Lunge Zuerich
Organisme : Lungenliga Bern
Organisme : Lungenliga Schweiz
Organisme : Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
Informations de copyright
© 2024 The Author(s). Pediatric Pulmonology published by Wiley Periodicals LLC.
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